Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Thomas A, Nicholas"'
Autor:
Louise Waite, Jeffrey Lee, Fiona Stanaway, Arjun Krishnan, Anupa Pathak, Thomas Blyth Nicholas
Publikováno v:
BMJ Open, Vol 14, Iss 9 (2024)
Background Despite a potentially greater burden of dementia, racial and ethnic minority populations around the world may be more likely to be excluded from research examining risk factors for incident dementia. We aimed to systematically investigate
Externí odkaz:
https://doaj.org/article/7d111b04ac0e47868e13cfaca8cfc8a3
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract Background Identification of deleterious genetic variants using DNA sequencing data relies on increasingly detailed filtering strategies to isolate the small subset of variants that are more likely to underlie a disease phenotype. Datasets r
Externí odkaz:
https://doaj.org/article/3c489c445f2642d092d45bb8ad2d7c20
Autor:
Thomas J. Nicholas, Michael J. Cormier, Xiaomeng Huang, Yi Qiao, Gabor T. Marth, Aaron R. Quinlan
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-11 (2021)
Abstract Background DNA sequencing has unveiled extensive tumor heterogeneity in several different cancer types, with many exhibiting diverse subclonal populations. Identifying and tracing mutations throughout the expansion and progression of a tumor
Externí odkaz:
https://doaj.org/article/e1da1938fbef4e359f6fe7d05b573c8c
Autor:
Thomas J. Nicholas, Najla Al‐Sweel, Andrew Farrell, Rong Mao, Pinar Bayrak‐Toydemir, Christine E. Miller, Dawn Bentley, Rachel Palmquist, Barry Moore, Edgar J. Hernandez, Michael J. Cormier, Eric Fredrickson, Katherine Noble, Shawn Rynearson, Carson Holt, Mary Anne Karren, Joshua L. Bonkowsky, Martin Tristani‐Firouzi, Mark Yandell, Gabor Marth, Aaron R. Quinlan, Luca Brunelli, Reha M. Toydemir, Brian J. Shayota, John C. Carey, Steven E. Boyden, Sabrina Malone Jenkins
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 10, Iss 4, Pp n/a-n/a (2022)
Abstract Background Genetic disorders contribute to significant morbidity and mortality in critically ill newborns. Despite advances in genome sequencing technologies, a majority of neonatal cases remain unsolved. Complex structural variants (SVs) of
Externí odkaz:
https://doaj.org/article/1827760dc59544598719c7df6f5aa0f2
Autor:
Metcalf, Benjamin J., Spring, Justin B., Humphreys, Peter C., Thomas-peter, Nicholas, Barbieri, Marco, Kolthammer, W. Steven, Jin, Xian-min, Langford, Nathan K., Kundys, Dmytro, Gates, James C., Smith, Brian J., Smith, Peter G. R., Walmsley, Ian A.
Quantum teleportation is a fundamental concept in quantum physics which now finds important applications at the heart of quantum technology including quantum relays, quantum repeaters and linear optics quantum computing (LOQC). Photonic implementatio
Externí odkaz:
http://arxiv.org/abs/1409.4267
Autor:
Spring, Justin B., Salter, Patrick S., Metcalf, Benjamin J., Humphreys, Peter C., Moore, Merritt, Thomas-Peter, Nicholas, Barbieri, Marco, Jin, Xian-Min, Langford, Nathan K., Kolthammer, W. Steven, Booth, Martin J., Walmsley, Ian A.
Publikováno v:
Optics Express, Vol. 21, Issue 11, pp. 13522-13532 (2013)
A key obstacle to the experimental realization of many photonic quantum-enhanced technologies is the lack of low-loss sources of single photons in pure quantum states. We demonstrate a promising solution: generation of heralded single photons in a si
Externí odkaz:
http://arxiv.org/abs/1304.7781
Autor:
Spring, Justin B., Metcalf, Benjamin J., Humphreys, Peter C., Kolthammer, W. Steven, Jin, Xian-Min, Barbieri, Marco, Datta, Animesh, Thomas-Peter, Nicholas, Langford, Nathan K., Kundys, Dmytro, Gates, James C., Smith, Brian J., Smith, Peter G. R., Walmsley, Ian A.
Publikováno v:
Science 339 798-801 (2013)
While universal quantum computers ideally solve problems such as factoring integers exponentially more efficiently than classical machines, the formidable challenges in building such devices motivate the demonstration of simpler, problem-specific alg
Externí odkaz:
http://arxiv.org/abs/1212.2622
Autor:
Metcalf, Benjamin J., Thomas-Peter, Nicholas, Spring, Justin B., Kundys, Dmytro, Broome, Matthew A., Humphreys, Peter, Jin, Xian-Min, Barbieri, Marco, Kolthammer, W. Steven, Gates, James C., Smith, Brian J., Langford, Nathan K., Smith, Peter G. R., Walmsley, Ian A.
Publikováno v:
Nature Communications 4 1356 (2013)
Increasing the complexity of quantum photonic devices is essential for many optical information processing applications to reach a regime beyond what can be classically simulated, and integrated photonics has emerged as a leading platform for achievi
Externí odkaz:
http://arxiv.org/abs/1208.4575
Autor:
Gerrits, Thomas, Thomas-Peter, Nicholas, Gates, James C., Lita, Adriana E., Metcalf, Benjamin J., Calkins, Brice, Tomlin, Nathan A., Fox, Anna E., Linares, Antía Lamas, Spring, Justin B., Langford, Nathan K., Mirin, Richard P., Smith, Peter G. R., Walmsley, Ian A., Nam, Sae Woo
Publikováno v:
Phys. Rev. A 84, 060301(R) (2011)
Integration is currently the only feasible route towards scalable photonic quantum processing devices that are sufficiently complex to be genuinely useful in computing, metrology, and simulation. Embedded on-chip detection will be critical to such de
Externí odkaz:
http://arxiv.org/abs/1107.5557
Autor:
Thomas-Peter, Nicholas, Langford, Nathan K, Datta, Animesh, Zhang, Lijian, Smith, Brian J, Spring, Justin B, Metcalf, Benjamin J, Coldenstrodt-Ronge, Hendrik B, Hu, Michael, Nunn, Joshua, Walmsley, Ian A
Publikováno v:
New J. Phys. 13 055024 (2011)
Loss is a critical roadblock to achieving photonic quantum-enhanced technologies. We explore a modular platform for implementing integrated photonics experiments and consider the effects of loss at different stages of these experiments, including sta
Externí odkaz:
http://arxiv.org/abs/1104.1863