Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Thomas Verbrugghen"'
Autor:
Mathias, Glassner, Luca, Palmieri, Bryn D, Monnery, Thomas, Verbrugghen, Steven, Deleye, Sigrid, Stroobants, Steven, Staelens, Leonie, Wyffels, Richard, Hoogenboom
Publikováno v:
Biomacromolecules. 18(1)
Poly(2-alkyl-2-oxazoline)s (PAOx) have received increasing interest for biomedical applications. Therefore, it is of fundamental importance to gain an in-depth understanding of the biodistribution profile of PAOx. We report the biodistribution of pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e7c4106b0bb599da98f07beb9ba30db3
https://pubmed.ncbi.nlm.nih.gov/28064503
https://pubmed.ncbi.nlm.nih.gov/28064503
Autor:
Thomas Verbrugghen, Richard Hoogenboom, Luca Palmieri, Mathias Glassner, Steven Deleye, Sigrid Stroobants, Leonie Wyffels, Bryn D. Monnery, Steven Staelens
Publikováno v:
Biomacromolecules
Poly(2-alkyl-2-oxazoline)s (PAOx) have received increasing interest for biomedical applications. Therefore, it is of fundamental importance to gain an in-depth understanding of the biodistribution profile of PAOx. We report the biodistribution of pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f109b47618e42c603a747aa3b4de318f
https://hdl.handle.net/10067/1385200151162165141
https://hdl.handle.net/10067/1385200151162165141
Autor:
Mathias Glassner, Thomas Verbrugghen, Sigrid Stroobants, Bryn D. Monnery, Richard Hoogenboom, Steven Staelens, Leonie Wyffels
Publikováno v:
Journal of controlled release
Poly(2-oxazoline)s are a promising class of polymers for biomedical applications and a versatile alternative to poly(ethylene glycol)s (PEG). In this work, the pharmacokinetic behavior of well defined 89Zr-labeled poly(2-ethyl-2-oxazoline)s (PEtOx) w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db041810698cad8b5c95dcadaaebd0c
https://pubmed.ncbi.nlm.nih.gov/27235979
https://pubmed.ncbi.nlm.nih.gov/27235979
Autor:
Jenny Pouyez, Louis Maes, Pierre Vandurm, Thomas Verbrugghen, Johan Wouters, Serge Van Calenbergh
Publikováno v:
Journal of medicinal chemistry
To explore the hitherto successful derivatization of the alpha-carbon of fosmidomycin, a series of new a-substituted analogues was prepared. This was done by introduction of a heteroatom (N or O) in alpha-position to the phosphonate and using the res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf73c254785428964c3a4e73a9ee2bf
https://hdl.handle.net/10067/1100910151162165141
https://hdl.handle.net/10067/1100910151162165141
Autor:
Hans Nelis, Thomas Verbrugghen, Anne-Sophie Messiaen, Regina Ortmann, Serge Van Calenbergh, Martin Schlitzer, Tom Coenye, Charlotte Declerck
Publikováno v:
International journal of antimicrobial agents. 38(3)
The Burkholderia cepacia complex (BCC) is a group of 17 closely related opportunistic pathogens that are able to infect the respiratory tract of cystic fibrosis patients. BCC bacteria are intrinsically resistant to many antibiotics and are therefore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4408370e147d4767f57ea4b33ac6289f
https://pubmed.ncbi.nlm.nih.gov/21724375
https://pubmed.ncbi.nlm.nih.gov/21724375
Publikováno v:
Journal of medicinal chemistry
JOURNAL OF MEDICINAL CHEMISTRY
JOURNAL OF MEDICINAL CHEMISTRY
Three α-halogenated analogues of 3-(acetylhydroxyamino)propylphosphonic acid (FR900098) have been synthesized from diethyl but-3-enylphosphonate using a previously described method for the α-halogenation of alkylphosphonates. These analogues were e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9095da734ea978ca4652c47b5f8e525c
https://hdl.handle.net/10067/827970151162165141
https://hdl.handle.net/10067/827970151162165141
Autor:
Serge Van Calenbergh, Thomas Verbrugghen, Jochen Wiesner, Andreas Link, Timothy Haemers, Ulrik Hillaert, Dirk Giessmann, Martin Schlitzer, Regina Ortmann, Hassan Jomaa
Publikováno v:
BIOORGANIC & MEDICINAL CHEMISTRY
To expand the structure-activity relationships of fosmidomycin and FR900098, two potent antimalarials interfering with the MEP-pathway, we decided to replace a methylene group in beta-position of the phosphonate moiety of these leads by an oxygen ato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0f062c17d6fd0dde42f0065e9c6f56
https://pubmed.ncbi.nlm.nih.gov/18158249
https://pubmed.ncbi.nlm.nih.gov/18158249
Publikováno v:
Nuclear Medicine and Biology. 41:645
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1eea5ad6f6e4ed6a8bf92b91c35e9fb1
https://doi.org/10.1016/j.nucmedbio.2014.05.085
https://doi.org/10.1016/j.nucmedbio.2014.05.085
Publikováno v:
Journal of Medicinal Chemistry; Jul2010, Vol. 53 Issue 14, p5342-5346, 5p