The E. coli effector protein NleF is a caspase inhibitor.

Autor: Sonja Blasche, Mario Mörtl, Holger Steuber, Gabriella Siszler, Shahista Nisa, Frank Schwarz, Inna Lavrik, Thomas M A Gronewold, Klaus Maskos, Michael S Donnenberg, Dirk Ullmann, Peter Uetz, Manfred Kögl

Publikováno v: PLoS ONE, Vol 8, Iss 3, p e58937 (2013)

Enterohemorrhagic and enteropathogenic E. coli (EHEC and EPEC) can cause severe and potentially life-threatening infections. Their pathogenicity is mediated by at least 40 effector proteins which they inject into their host cells by a type-III secret

Externí odkaz: https://doaj.org/article/73b654b40a5d425fa7021d4c8ba38cf5

The position of hydrophobic residues tunes peptide self-assembly

Autor: Christian Bortolini, Chen Wang, Thomas M. A. Gronewold, Flemming Besenbacher, Lei Liu, Mingdong Dong

Publikováno v: Bortolini, C, Liu, L, Gronewold, T M A, Wang, C, Besenbacher, F & Dong, MD 2014, ' The position of hydrophobic residues tunes peptide self-assembly ', Soft Matter, vol. 10, no. 31, pp. 5656-5661 . https://doi.org/10.1039/c4sm01065e

The final structure and properties of synthetic peptides mainly depend on their sequence composition and experimental conditions. This work demonstrates that a variation in the positions of hydrophobic residues within a peptide sequence can tune the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02e0fd058c397ad53bb9cefe53e172a
https://doi.org/10.1039/c4sm01065e

act Operon Control of Developmental Gene Expression in Myxococcus xanthus

Autor: Dale Kaiser, Thomas M. A. Gronewold

Publikováno v: Journal of Bacteriology. 184:1172-1179

Cell-bound C-signal guides the building of a fruiting body and triggers the differentiation of myxospores. Earlier work has shown that transcription of the csgA gene, which encodes the C-signal, is directed by four genes of the act operon. To see how

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16134421571e0c1f52e466a95c728767
https://doi.org/10.1128/jb.184.4.1172-1179.2002

Effects of rhizopodin and latrunculin B on the morphology and on the actin cytoskeleton of mammalian cells

Autor: Hans Reichenbach, Florenz Sasse, Heinrich Lünsdorf, Thomas M. A. Gronewold

Publikováno v: Cell and Tissue Research. 295:121-129

The effects of the novel myxobacterial compound rhizopodin on mammalian cells were studied and compared with those of latrunculin B. Both substances induced adherently growing L929 mouse fibroblasts and PtK2 potoroo kidney cells to produce long, narr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fde7ab29ba6211a2e8c3b4ec90337a13
https://doi.org/10.1007/s004410051218

Kinetic binding analysis of aptamers targeting HIV-1 proteins by a combination of a microbalance array and mass spectrometry (MAMS)

Autor: Julia Blümer, Michael Famulok, Thomas M. A. Gronewold, Jessica Hierer, Frank Schäfer, Antje Baumgartner, Anne Kiwitz, Martin Zabe-Kühn, Eckhard Dr. Quandt, Michael Blind, Saleta Sierra, Tina Tillmann, Rolf Kaiser

Publikováno v: Journal of proteome research

An enhanced chip-based detection platform was developed by integrating a surface acoustic wave biosensor of the Love-wave type with protein identification by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-ToF MS).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::091b1f17d6b1d41d03472d4741e24702
https://pubmed.ncbi.nlm.nih.gov/19469583