Zobrazeno 1 - 10
of 273
pro vyhledávání: '"Thomas J. Meade"'
Autor:
Roxana E. Mitrut, Devin M. Stranford, Beth N. DiBiase, Jonathan M. Chan, Matthew D. Bailey, Minrui Luo, Clare S. Harper, Thomas J. Meade, Muzhou Wang, Joshua N. Leonard
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 7, Pp n/a-n/a (2024)
Abstract Extracellular vesicles (EVs) play key roles in diverse biological processes, transport biomolecules between cells and have been engineered for therapeutic applications. A useful EV bioengineering strategy is to express engineered proteins on
Externí odkaz:
https://doaj.org/article/fa08fc19a02f4b398365b7e2ccda7e35
Autor:
Toloo Taghian, Ana Rita Batista, Sarah Kamper, Michael Caldwell, Laura Lilley, Hao Li, Paola Rodriguez, Katerina Mesa, Shaokuan Zheng, Robert M. King, Matthew J. Gounis, Sophia Todeasa, Anne Maguire, Douglas R. Martin, Miguel Sena-Esteves, Thomas J. Meade, Heather L. Gray-Edwards
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 128-134 (2021)
Transformative results of adeno-associated virus (AAV) gene therapy in patients with spinal muscular atrophy and Leber’s congenital amaurosis led to approval of the first two AAV products in the United States to treat these diseases. These extraord
Externí odkaz:
https://doaj.org/article/c16bf88485644845ad32d3c283989ad8
Autor:
Meghan W. Dukes, Thomas J. Meade
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2376 (2022)
Basal Cell Carcinoma (BCC) is the most commonly diagnosed cancer worldwide. While the survivability of BCC is high, many patients are excluded from clinically available treatments due to health risks or personal choice. Further, patients with advance
Externí odkaz:
https://doaj.org/article/3b12c933aac5401da725c705713b7332
Publikováno v:
Journal of the American Chemical Society. 145:10045-10050
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5305aab9aae0bad804254e53e856a6f
https://doi.org/10.1021/jacs.2c13672
https://doi.org/10.1021/jacs.2c13672
Autor:
Laura M. Lilley, Sarah G. Kamper, Thomas J. Meade, Ana Rita Batista, Miguel Sena-Esteves, Hao Li, Matthew J. Gounis, Douglas R. Martin, Shaokuan Zheng, Katerina Mesa, Robert M. King, Paola Rodriguez, Toloo Taghian, Heather L. Gray-Edwards, Michael A. Caldwell, Anne S Maguire, Sophia H. Todeasa
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss, Pp 128-134 (2021)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Transformative results of adeno-associated virus (AAV) gene therapy in patients with spinal muscular atrophy and Leber’s congenital amaurosis led to approval of the first two AAV products in the United States to treat these diseases. These extraord
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::319f96d30cb3fb7fb4f50fedb13829ec
http://www.sciencedirect.com/science/article/pii/S2329050121001297
http://www.sciencedirect.com/science/article/pii/S2329050121001297
Publikováno v:
Journal of the American Chemical Society. 143:17097-17108
Prostate-specific membrane antigen (PSMA) is a transmembrane protein that is highly expressed in aggressive prostate cancer (PCa) and has been extensively studied as a PCa diagnostic imaging biomarker. Multiple imaging modalities have exploited PSMA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce44d75c760f4ab684e699e087684946
https://doi.org/10.1021/jacs.1c07377
https://doi.org/10.1021/jacs.1c07377
Publikováno v:
Molecular Bio-Sensors and the Role of Metal Ions ISBN: 9781003229971
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ecc573b425c392b0ba2a96f87d2db65
https://doi.org/10.1201/9781003229971-9
https://doi.org/10.1201/9781003229971-9
Autor:
Xinning Wang, Christopher A Flask, Sarah Springer, Hao Li, Dong Luo, Gopalakrishnan Ramamurthy, Bernadette O. Erokwu, Andrew Johnson, James P. Basilion, Clemens Burda, Jason Lou, Thomas J. Meade
Publikováno v:
Nano Lett
Adjuvant radiotherapy is frequently prescribed to treat cancer. To minimize radiation-related damage to healthy tissue, it requires high precision in tumor localization and radiation dose delivery. This can be achieved by MR guidance and targeted amp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525017aa6579b907c6ca0b785c0c8961
https://doi.org/10.1021/acs.nanolett.0c02487
https://doi.org/10.1021/acs.nanolett.0c02487
Publikováno v:
ACS Chemical Biology. 15:334-341
Ca(II) ions are critical for the proper function of neurons by contributing to synaptic signaling and regulating neuronal plasticity. Dysregulation of Ca(II) is associated with a number of pathologies that cause neurodegeneration; therefore the abili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd045549fe2d43d1d793ab5c6cc27486
https://doi.org/10.1021/acschembio.9b00638
https://doi.org/10.1021/acschembio.9b00638
Autor:
Meghan W. Dukes, Elizabeth A. Bajema, Tyler J. Whittemore, Robert A. Holmgren, Thomas J. Meade
Publikováno v:
Bioconjugate chemistry. 33(4)
The Hedgehog (Hh) signaling pathway is integral for embryonic development and normal cell maintenance. However, aberrant expression of the Hh pathway is recognized as the oncogenic driving force for basal cell carcinoma (BCC). Current chemotherapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f549ed8d0e380946ba94889389e940de
https://pubmed.ncbi.nlm.nih.gov/35271256
https://pubmed.ncbi.nlm.nih.gov/35271256