Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Thomas F. Spande"'
Autor:
Donovan J. Robinson, Conor T. Hogan, William A. Shear, Ralph A. Saporito, Thomas F. Spande, Dylan M. Guthrie, Robert Mesibov, Tappey H. Jones
Publikováno v:
Journal of Natural Products. 81:171-177
Millipedes (Diplopoda) are well known for their toxic or repellent defensive secretions. As part of a larger investigation, we describe the chemical constituents of 14 species of Tasmanian millipedes in seven genera. Six species in the genus Gasterog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac3668ceff4c315658b1ba328091d93
https://doi.org/10.1021/acs.jnatprod.7b00806
https://doi.org/10.1021/acs.jnatprod.7b00806
Publikováno v:
Experimental and Applied Acarology. 67:317-333
The opisthonotal (oil) glands of oribatid mites are the source of a wide diversity of taxon-specific defensive chemicals, and are likely the location for the more than 90 alkaloids recently identified in oribatids. Although originally recognized in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31ebc0aafb98103f8569e158c5e2a26a
https://doi.org/10.1007/s10493-015-9962-8
https://doi.org/10.1007/s10493-015-9962-8
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 4, Iss 1, p 6 (2008)
A short synthesis of the postulated structure for indolizidine alkaloid 259B with the hydrogens at C5 and C9 entgegen has been achieved with complete control of stereochemistry at C5. Both diastereoisomers at C8 were obtained, but neither proved to b
Externí odkaz:
https://doaj.org/article/de6e25bf75344cd2ab97f34e09d0be4b
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 3, Iss 1, p 29 (2007)
BackgroundThe 5,8-disubstituted indolizidines are the largest class of poison-frog alkaloids found in anuran skin, and are of considerable interest because of their inhibitory effects on the neuronal nicotinic acetylcholine receptors. Many synthetic
Externí odkaz:
https://doaj.org/article/52f04af198d64286b9ad8a7411c72197
Autor:
Soushi Kobayashi, Naoki Toyooka, Dejun Zhou, Hiroshi Tsuneki, Tsutomu Wada, Toshiyasu Sasaoka, Hideki Sakai, Hideo Nemoto, H. Martin Garraffo, Thomas F. Spande, John W. Daly
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 3, Iss 1, p 30 (2007)
BackgroundThe 5,8-disubstituted indolizidines constitute the largest class of poison-frog alkaloids. Some alkaloids have been shown to act as noncompetitive blockers at nicotinic acetylcholine receptors but the proposed structures and the biological
Externí odkaz:
https://doaj.org/article/90e82e3208b8463c879a1a11df9cb3c2
Autor:
Tappey H. Jones, Thomas F. Spande, Rachelle M. M. Adams, H. Martin Garraffo, Tetsuo Kaneko, Ted R. Schultz
Publikováno v:
Journal of Natural Products. 75:1930-1936
Workers of the ant Carebarella bicolor collected in Panama were found to have two major poison-frog alkaloids, cis- and trans-fused decahydroquinolines (DHQs) of the 269AB type, four minor 269AB isomers, two minor 269B isomers, and three isomers of D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d314e7d0157b4afab27112da68ced148
https://doi.org/10.1021/np300485v
https://doi.org/10.1021/np300485v
Publikováno v:
Chemoecology. 22:159-168
Herein we review what is known about the chemical ecology of poison frogs with a focus on dendrobatid poison frogs. While five anuran families are known to have an alkaloid-derived chemical defense, the dendrobatids have been studied in greatest deta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8770c3ca110559eb0562c833eecc54b
https://doi.org/10.1007/s00049-011-0088-0
https://doi.org/10.1007/s00049-011-0088-0
Publikováno v:
Journal of Natural Products. 73:331-337
The skin of the Ecuadorian poison frog Epipedobates anthonyi contains the potent nicotinic agonists epibatidine (1) and N-methylepibatidine (3). In addition, a condensed tetracyclic epibatidine congener has been identified with activity at nicotinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee0352f537a15843fdac6f8b9f73513b
https://doi.org/10.1021/np900727e
https://doi.org/10.1021/np900727e
Publikováno v:
Journal of Natural Products. 72:1110-1114
The dominant alkaloids previously identified in skin extracts of Amazonian dendrobatid frogs of the genus Ameerega are histrionicotoxins and 2,5-disubstituted decahydroquinolines. Analysis of alkaloids in skin extracts of Ameerega picta from Bolivia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::714365d7964d6a26fbac1c0d2da2ca8e
https://doi.org/10.1021/np900094v
https://doi.org/10.1021/np900094v
Autor:
Gordon D. Sturgeon, H. Martin Garraffo, Richard H. Blaauw, John W. Daly, Thomas F. Spande, Shaun R. Patel, Richard W. Fitch
Publikováno v:
Journal of Natural Products. 72:243-247
In 2003, we reported the isolation, structure elucidation, and pharmacology of epiquinamide (1), a novel alkaloid isolated from an Ecuadoran poison frog, Epipedobates tricolor. Since then, several groups, including ours, have undertaken synthetic eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e30ad7a5864a380158191eb20e841243
https://doi.org/10.1021/np8005452
https://doi.org/10.1021/np8005452