Quantitative iron–neuromelanin MRI associates with motor severity in Parkinson's disease and matches radiological disease classification

Autor: Septian Hartono, Robert Chun Chen, Thomas Welton, An Sen Tan, Weiling Lee, Peik Yen Teh, Celeste Chen, Wenlu Hou, Wei Ping Tham, Ee Wei Lim, Kumar M. Prakash, Yao-Chia Shih, Kuan Jin Lee, Louis C. S. Tan, Eng King Tan, Ling Ling Chan

Publikováno v: Frontiers in Aging Neuroscience, Vol 15 (2023)

BackgroundNeuromelanin- and iron-sensitive MRI studies in Parkinson's disease (PD) are limited by small sample sizes and lack detailed clinical correlation. In a large case–control PD cohort, we evaluated the diagnostic accuracy of quantitative iro

Externí odkaz: https://doaj.org/article/22b80cae64944df8a392343cf2594e04

Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset?

Autor: Kurt G. Schilling, François Rheault, Laurent Petit, Colin B. Hansen, Vishwesh Nath, Fang-Cheng Yeh, Gabriel Girard, Muhamed Barakovic, Jonathan Rafael-Patino, Thomas Yu, Elda Fischi-Gomez, Marco Pizzolato, Mario Ocampo-Pineda, Simona Schiavi, Erick J. Canales-Rodríguez, Alessandro Daducci, Cristina Granziera, Giorgio Innocenti, Jean-Philippe Thiran, Laura Mancini, Stephen Wastling, Sirio Cocozza, Maria Petracca, Giuseppe Pontillo, Matteo Mancini, Sjoerd B. Vos, Vejay N. Vakharia, John S. Duncan, Helena Melero, Lidia Manzanedo, Emilio Sanz-Morales, Ángel Peña-Melián, Fernando Calamante, Arnaud Attyé, Ryan P. Cabeen, Laura Korobova, Arthur W. Toga, Anupa Ambili Vijayakumari, Drew Parker, Ragini Verma, Ahmed Radwan, Stefan Sunaert, Louise Emsell, Alberto De Luca, Alexander Leemans, Claude J. Bajada, Hamied Haroon, Hojjatollah Azadbakht, Maxime Chamberland, Sila Genc, Chantal M.W. Tax, Ping-Hong Yeh, Rujirutana Srikanchana, Colin D. Mcknight, Joseph Yuan-Mou Yang, Jian Chen, Claire E. Kelly, Chun-Hung Yeh, Jerome Cochereau, Jerome J. Maller, Thomas Welton, Fabien Almairac, Kiran K Seunarine, Chris A. Clark, Fan Zhang, Nikos Makris, Alexandra Golby, Yogesh Rathi, Lauren J. O'Donnell, Yihao Xia, Dogu Baran Aydogan, Yonggang Shi, Francisco Guerreiro Fernandes, Mathijs Raemaekers, Shaun Warrington, Stijn Michielse, Alonso Ramírez-Manzanares, Luis Concha, Ramón Aranda, Mariano Rivera Meraz, Garikoitz Lerma-Usabiaga, Lucas Roitman, Lucius S. Fekonja, Navona Calarco, Michael Joseph, Hajer Nakua, Aristotle N. Voineskos, Philippe Karan, Gabrielle Grenier, Jon Haitz Legarreta, Nagesh Adluru, Veena A. Nair, Vivek Prabhakaran, Andrew L. Alexander, Koji Kamagata, Yuya Saito, Wataru Uchida, Christina Andica, Masahiro Abe, Roza G. Bayrak, Claudia A.M. Gandini Wheeler-Kingshott, Egidio D'Angelo, Fulvia Palesi, Giovanni Savini, Nicolò Rolandi, Pamela Guevara, Josselin Houenou, Narciso López-López, Jean-François Mangin, Cyril Poupon, Claudio Román, Andrea Vázquez, Chiara Maffei, Mavilde Arantes, José Paulo Andrade, Susana Maria Silva, Vince D. Calhoun, Eduardo Caverzasi, Simone Sacco, Michael Lauricella, Franco Pestilli, Daniel Bullock, Yang Zhan, Edith Brignoni-Perez, Catherine Lebel, Jess E Reynolds, Igor Nestrasil, René Labounek, Christophe Lenglet, Amy Paulson, Stefania Aulicka, Sarah R. Heilbronner, Katja Heuer, Bramsh Qamar Chandio, Javier Guaje, Wei Tang, Eleftherios Garyfallidis, Rajikha Raja, Adam W. Anderson, Bennett A. Landman, Maxime Descoteaux

Publikováno v: NeuroImage, Vol 243, Iss , Pp 118502- (2021)

White matter bundle segmentation using diffusion MRI fiber tractography has become the method of choice to identify white matter fiber pathways in vivo in human brains. However, like other analyses of complex data, there is considerable variability i

Externí odkaz: https://doaj.org/article/d2f43c7d890749b4be784f2e814a17e8

Microstructure of Brain Nuclei in Early Parkinson’s Disease: Longitudinal Diffusion Kurtosis Imaging

Autor: Thomas Welton, Septian Hartono, Yao-Chia Shih, Weiling Lee, Pik Hsien Chai, Say Lee Chong, Samuel Yong Ern Ng, Nicole Shuang Yu Chia, Xinyi Choi, Dede Liana Heng, Eng-King Tan, Louis C.S. Tan, Ling-Ling Chan

Publikováno v: Journal of Parkinson's Disease. 13:233-242

Background: Diffusion kurtosis imaging provides in vivo measurement of microstructural tissue characteristics and could help guide management of Parkinson’s disease. Objective: To investigate longitudinal diffusion kurtosis imaging changes on magne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1dd2b347b5adec70a1ea282cbc1716f4
https://doi.org/10.3233/jpd-225095

Solvents and Solvent Effects in Organic Chemistry. 4. Aufl. Von Christian Reichardt und Thomas Welton

Autor: Ralf Giernoth

Publikováno v: Angewandte Chemie. 123:11485-11485

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8cc454c745cc7c76da9a96415667888a
https://doi.org/10.1002/ange.201105531

Diffusion kurtosis imaging detects subclinical white matter abnormalities in Phenylketonuria

Autor: Sarah C. Hellewell, Thomas Welton, Kate Eisenhuth, Michel C. Tchan, Stuart M. Grieve

Publikováno v: NeuroImage: Clinical, Vol 29, Iss , Pp 102555- (2021)

Objective: Phenylketonuria (PKU) is an autosomal recessive disorder whereby deficiencies in phenylalanine metabolism cause progressive neurological dysfunction. Managing PKU is challenging, with disease monitoring focussed on short-term phenylalanine

Externí odkaz: https://doaj.org/article/fb5db6c61ae74cd0bfee97d7ea7b4b0e