Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Thomas, Urup"'
Autor:
Sveinn Pálsson, Stefano Cerri, Hans Skovgaard Poulsen, Thomas Urup, Ian Law, Koen Van Leemput
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Survival prediction models can potentially be used to guide treatment of glioblastoma patients. However, currently available MR imaging biomarkers holding prognostic information are often challenging to interpret, have difficulties generaliz
Externí odkaz:
https://doaj.org/article/4ba34c5acbba48efa1f35eb357a11234
Autor:
Thomas Urup, Linn Gillberg, Katja Kaastrup, Maya Jeje Schuang Lü, Signe Regner Michaelsen, Vibeke Andrée Larsen, Ib Jarle Christensen, Helle Broholm, Ulrik Lassen, Kirsten Grønbæk, Hans Skovgaard Poulsen
Publikováno v:
Molecular Oncology, Vol 14, Iss 5, Pp 964-973 (2020)
Patients with recurrent glioblastoma achieving response to bevacizumab combined with chemotherapy have clinical improvement and prolonged survival. High gene expression of angiotensinogen (AGT) is associated with a poor bevacizumab response. Because
Externí odkaz:
https://doaj.org/article/a869f372b7954f5c8bf9715dcc5ecaf3
Autor:
Armita Armina Abedi, Kirsten Grunnet, Ib Jarle Christensen, Signe Regner Michaelsen, Aida Muhic, Søren Møller, Benedikte Hasselbalch, Hans Skovgaard Poulsen, Thomas Urup
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundGlioblastoma patients administered standard therapies, comprising maximal surgical resection, radiation therapy with concomitant and adjuvant temozolomide, have a variable prognosis with a median overall survival of 15–16 months and a 2-y
Externí odkaz:
https://doaj.org/article/fd68eefa924d45eca16fee3891f5d342
Autor:
Thomas Urup, Line Mærsk Staunstrup, Signe Regner Michaelsen, Kristoffer Vitting-Seerup, Marc Bennedbæk, Anders Toft, Lars Rønn Olsen, Lars Jønson, Shohreh Issazadeh-Navikas, Helle Broholm, Petra Hamerlik, Hans Skovgaard Poulsen, Ulrik Lassen
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-10 (2017)
Abstract Background Bevacizumab combined with chemotherapy produces clinical durable response in 25–30% of recurrent glioblastoma patients. This group of patients has shown improved survival and quality of life. The aim of this study was to investi
Externí odkaz:
https://doaj.org/article/d6cd520ea2664653a177429de6ebebb1
Autor:
Thomas Urup, Signe Regner Michaelsen, Lars Rønn Olsen, Anders Toft, Ib Jarle Christensen, Kirsten Grunnet, Ole Winther, Helle Broholm, Michael Kosteljanetz, Shohreh Issazadeh-Navikas, Hans Skovgaard Poulsen, Ulrik Lassen
Publikováno v:
Molecular Oncology, Vol 10, Iss 8, Pp 1160-1168 (2016)
Background Bevacizumab combination therapy is among the most frequently used treatments in recurrent glioblastoma and patients who achieve response to bevacizumab have improved survival as well as quality of life. Accordingly, the aim of this study w
Externí odkaz:
https://doaj.org/article/bd720aa45e524484b30672fdd8de1366
Autor:
Dorte Schou Nørøxe, Lise Barlebo Ahlborn, Vincent Fougner, Thomas Urup, Benedikte Hasselbalch, Christina Westmose Yde, Hans Skovgaard Poulsen, Ulrik Lassen
Publikováno v:
Cancer Research. 83:1046-1046
Introduction: Glioblastoma (GBM) is an aggressive brain cancer with a median overall survival of 16-24 months. Evaluation of treatment effect can be difficult as pseudo progression is seen in approximately 15% of patients. Hence, effective treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::003e8bed119d79639d79321f54f6062a
https://doi.org/10.1158/1538-7445.am2023-1046
https://doi.org/10.1158/1538-7445.am2023-1046
Autor:
Signe Regner Michaelsen, Derya Aslan, Thomas Urup, Hans Skovgaard Poulsen, Kirsten Grønbæk, Helle Broholm, Lasse Sommer Kristensen
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 3, p 679 (2018)
Complete surgical resection of glioblastoma is difficult due to the invasive nature of this primary brain tumor, for which the molecular mechanisms behind remain poorly understood. The three human ELMO genes play key roles in cellular motility, and h
Externí odkaz:
https://doaj.org/article/79ceb1c8683a4ca7869165e8fc786994
Autor:
Mette Kjoelhede Nedergaard, Signe Regner Michaelsen, Thomas Urup, Helle Broholm, Henrik El Ali, Hans Skovgaard Poulsen, Marie-Thérése Stockhausen, Andreas Kjaer, Ulrik Lassen
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0115315 (2015)
BACKGROUND:Conflicting data exist for anti-cancer effects of anti-placental growth factor (anti-PlGF) in combination with anti-VEGF. Still, this treatment combination has not been evaluated in intracranial glioblastoma (GBM) xenografts. In clinical s
Externí odkaz:
https://doaj.org/article/7b43c0caac654dda8e8a4a5debb4d251
Autor:
Vibeke Andrée Larsen, Jane Skjøth-Rasmussen, Sofie Mathilde Jacobsen, Kirsten Grunnet, Asma Bashir, Thomas Urup, Sören Möller, Ian Law, Helle Broholm, Hans Skovgaard Poulsen, Otto M. Henriksen
Publikováno v:
Neuro Oncol
BackgroundDiagnostic accuracy in previous studies of O-(2-[18F]-fluoroethyl)-L-tyrosine (18F-FET) PET in patients with suspected recurrent glioma may be influenced by prolonged dynamic PET acquisitions, heterogeneous populations, different non–stan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1fc5c5cd05117dd8f99438503e84a9e
https://doi.org/10.1093/neuonc/noz166
https://doi.org/10.1093/neuonc/noz166
Autor:
Hans Skovgaard Poulsen, Kirsten Grunnet, Ulrik Lassen, Vibeke Andrée Larsen, Thomas Urup, Ib Jarle Christensen, Helle Broholm, Michael Kosteljanetz, Babloo Lukram, Signe Regner Michaelsen, Anders Toft
Publikováno v:
Cancer Investigation. 36:165-174
Predictive biomarkers and prognostic models are required to identify recurrent grade III glioma patients who benefit from existing treatment. In this study of 62 recurrent grade III glioma patients, a range of clinical and paraclinical factors are te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f836cdaa566accd6b334c5c1ea86369
https://doi.org/10.1080/07357907.2018.1430818
https://doi.org/10.1080/07357907.2018.1430818