Zobrazeno 1 - 10
of 656
pro vyhledávání: '"Thomas, Unger"'
Autor:
Sonali R. Gnanenthiran, Claudio Borghi, Dylan Burger, Bruno Caramelli, Fadi Charchar, Julio A. Chirinos, Jordana B. Cohen, Antoine Cremer, Gian Luca Di Tanna, Alexandre Duvignaud, Daniel Freilich, D. H. Frank Gommans, Abraham E. Gracia‐Ramos, Thomas A. Murray, Facundo Pelorosso, Neil R. Poulter, Michael A. Puskarich, Konstantinos D. Rizas, Rodolfo Rothlin, Markus P. Schlaich, Michael Schreinlecher, Ulrike Muscha Steckelings, Abhinav Sharma, George S. Stergiou, Christopher J. Tignanelli, Maciej Tomaszewski, Thomas Unger, Roland R. J. van Kimmenade, Richard D. Wainford, Bryan Williams, Anthony Rodgers, Aletta E. Schutte
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 17 (2022)
Background Published randomized controlled trials are underpowered for binary clinical end points to assess the safety and efficacy of renin‐angiotensin system inhibitors (RASi) in adults with COVID‐19. We therefore performed a meta‐analysis to
Externí odkaz:
https://doaj.org/article/1f10e3a056824f04b0479f27b6c3925f
Autor:
Bettina Sehnert, Veronica Valero-Esquitino, Georg Schett, Thomas Unger, Ulrike Muscha Steckelings, Reinhard Edmund Voll
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The angiotensin AT2 receptor (AT2R) is a main receptor of the protective arm of the renin-angiotensin system and exerts for instance anti-inflammatory effects. The impact of AT2R stimulation on autoimmune diseases such as rheumatoid arthritis (RA) is
Externí odkaz:
https://doaj.org/article/fdd26607d5eb4403a69ca9f4854df224
Publikováno v:
Blood Pressure, Vol 29, Iss 6, Pp 357-361 (2020)
Purpose Hypertension is the most important risk factor for disease and premature death. Treatment strategies adjusted for cardiovascular risk have been proposed in guidelines, but real-life treatment strategies for patients with newly diagnosed hyper
Externí odkaz:
https://doaj.org/article/207e90c640904368b39f14ed55bf3b9c
Autor:
Marion Peyrou, Rubén Cereijo, Tania Quesada-López, Laura Campderrós, Aleix Gavaldà-Navarro, Laura Liñares-Pose, Elena Kaschina, Thomas Unger, Miguel López, Marta Giralt, Francesc Villarroya
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Brown adipose tissue, known produce heat by metabolizing fat, is also secretes molecules capable of communicating with other organs. Here the authors show that brown adipose tissue secretes kininogen, a component of heat system regulation, that provi
Externí odkaz:
https://doaj.org/article/150ca23506ff4dd1a06c23947991322f
Autor:
Bettina Greiner, Manuela Sommerfeld, Ulrich Kintscher, Thomas Unger, Kai Kappert, Elena Kaschina
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3271 (2022)
Cannabinoids (CB) are implicated in cardiovascular diseases via the two main receptor subtypes CB1R and CB2R. This study investigated whether cannabinoids regulate the activity of matrix metalloproteases (MMP-2, MMP-9) in vascular smooth muscle cells
Externí odkaz:
https://doaj.org/article/29b7ba1c843a40d5b7d2263122354b23
Autor:
Claudio Borghi, Dylan Burger, Fadi Charchar, Neil R Poulter, Ulrike Muscha Steckelings, Maciej Tomaszewski, Thomas Unger, Richard D Wainford, Aletta E Schutte
Publikováno v:
BMJ Open, Vol 11, Iss 2 (2021)
Introduction Whether ACE inhibitors (ACEi) or angiotensin II receptor blocker (ARB) therapy should be continued, initiated or ceased in patients with COVID-19 is uncertain. Given the widespread use of ACEi/ARBs worldwide, guidance on the use of these
Externí odkaz:
https://doaj.org/article/5ed6eafb09d144878bd26b19183d0b0d
Autor:
Aletta E Schutte, Tazeen H Jafar, Neil R Poulter, Albertino Damasceno, Nadia A Khan, Peter M Nilsson, Jafar Alsaid, Dinesh Neupane, Kazuomi Kario, Hind Beheiry, Sofie Brouwers, Dylan Burger, Fadi J Charchar, Myeong-Chan Cho, Tomasz J Guzik, Ghazi F Haji Al-Saedi, Muhammad Ishaq, Hiroshi Itoh, Erika S W Jones, Taskeen Khan, Yoshihiro Kokubo, Praew Kotruchin, Elizabeth Muxfeldt, Augustine Odili, Mansi Patil, Udaya Ralapanawa, Cesar A Romero, Markus P Schlaich, Abdulla Shehab, Ching Siew Mooi, U Muscha Steckelings, George Stergiou, Rhian M Touyz, Thomas Unger, Richard D Wainford, Ji-Guang Wang, Bryan Williams, Brandi M Wynne, Maciej Tomaszewski
Publikováno v:
Cardiovascular Research. 119:381-409
Abstract Raised blood pressure (BP) is the leading cause of preventable death in the world. Yet, its global prevalence is increasing, and it remains poorly detected, treated, and controlled in both high- and low-resource settings. From the perspectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a3e1b6b62af2d9844db53c6a1b3464
https://doi.org/10.1093/cvr/cvac130
https://doi.org/10.1093/cvr/cvac130
Autor:
U. Muscha Steckelings, Robert E. Widdop, Edward D. Sturrock, Lizelle Lubbe, Tahir Hussain, Elena Kaschina, Thomas Unger, Anders Hallberg, Robert M. Carey, Colin Sumners
Publikováno v:
Pharmacological Reviews. 74:1051-1135
Discovered more than 30 years ago, the angiotensin AT2 receptor (AT2R) has evolved from a binding site with unknown function to a firmly established major effector within the protective arm of the renin-angiotensin system (RAS) and a target for new d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed01bea095fdd625441059db2d80f05
https://doi.org/10.1124/pharmrev.120.000281
https://doi.org/10.1124/pharmrev.120.000281
Publikováno v:
Blood Pressure, Vol 29, Iss 6, Pp 339-340 (2020)
Externí odkaz:
https://doaj.org/article/36b38bd0543a4492a53fcf48ba272366
Autor:
Ali Raza, Thomas Unger, Matthew Boyd, Eric B Munson, Parul Sohal, Ulrich Drepper, Richard Jones, Daniel Bristot De Oliveira, Larry Woodman, Renato Mancuso, Jonathan Appavoo, Orran Krieger
Publikováno v:
Proceedings of the Eighteenth European Conference on Computer Systems.
This paper presents Unikernel Linux (UKL), a path toward integrating unikernel optimization techniques in Linux, a general purpose operating system. UKL adds a configuration option to Linux allowing for a single, optimized process to link with the ke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa6983a5ed40d1c3a949b43b367a0736
https://doi.org/10.1145/3552326.3587458
https://doi.org/10.1145/3552326.3587458