Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Thomas, Tängdén"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract There is limited data on host-specific genetic determinants of susceptibility to bacterial and viral infections. Genome-wide association studies using large population cohorts can be a first step towards identifying patients prone to infecti
Externí odkaz:
https://doaj.org/article/0688e3408d644d5a9ab249d421044c3f
Autor:
Christer Malmberg, Jessie Torpner, Jenny Fernberg, Håkan Öhrn, Jonas Ångström, Cecilia Johansson, Thomas Tängdén, Johan Kreuger
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The rapidly changing landscape of antimicrobial resistance poses a challenge for empirical antibiotic therapy in severely ill patients and highlights the need for fast antibiotic susceptibility diagnostics to guide treatment. Traditional methods for
Externí odkaz:
https://doaj.org/article/9c19aa8bd51d4974b263aaef16689b23
Publikováno v:
Antibiotics, Vol 11, Iss 11, p 1646 (2022)
Double-carbapenem combinations have shown synergistic potential against carbapenemase-producing Enterobacterales, but data remain inconclusive. This study evaluated the activity of double-carbapenem combinations against 51 clinical KPC-2-, OXA-48-, N
Externí odkaz:
https://doaj.org/article/b787c6461766491e82e1f2169ee6b7cc
Autor:
Elias Dahdouh, Lisa Allander, Linda Falgenhauer, Bogdan I. Iorga, Stefano Lorenzetti, Íñigo Marcos-Alcalde, Nathaniel I. Martin, Luis Martínez-Martínez, Jesús Mingorance, Thierry Naas, Joseph E. Rubin, Francesca Spyrakis, Thomas Tängdén, Paulino Gómez-Puertas
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9746 (2022)
The EPIC consortium brings together experts from a wide range of fields that include clinical, molecular and basic microbiology, infectious diseases, computational biology and chemistry, drug discovery and design, bioinformatics, biochemistry, biophy
Externí odkaz:
https://doaj.org/article/5a1cf8dde3184d1bada38a6ebc146bfa
Autor:
Annelies Verbon, John Conly, R I Helou, Gaud Catho, Annabel Peyravi Latif, Johan Mouton, M Hulscher, Steven Teerenstra, Benedikt D Huttner, Thomas Tängdén
Publikováno v:
BMJ Open, Vol 10, Iss 6 (2020)
Introduction With the widespread use of electronic health records and handheld electronic devices in hospitals, informatics-based antimicrobial stewardship interventions hold great promise as tools to promote appropriate antimicrobial drug prescribin
Externí odkaz:
https://doaj.org/article/283d4e69e2ff471fbaf8442deaf1e2ea
Autor:
Pikkei Wistrand-Yuen, Christer Malmberg, Nikos Fatsis-Kavalopoulos, Moritz Lübke, Thomas Tängdén, Johan Kreuger
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT Many patients with severe infections receive inappropriate empirical treatment, and rapid detection of bacterial antibiotic susceptibility can improve clinical outcome and reduce mortality. To this end, we have developed a multiplex fluidic
Externí odkaz:
https://doaj.org/article/cd2109e2d337444da3fa1a0aa15063c2
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0211098 (2019)
OBJECTIVES:This study aimed to retrospectively assess the clinical outcome with nitrofurantoin and pivmecillinam for lower urinary tract infections (UTI) in men. Patients treated with trimethoprim were also included for comparison. METHODS:All prescr
Externí odkaz:
https://doaj.org/article/5846824041314c6da51888860f9c22f1
Autor:
Pier Giorgio Cojutti, Aaron J. Heffernan, Thomas Tängdén, Paola Della Siega, Carlo Tascini, Jason A. Roberts, Federico Pea
Publikováno v:
Antimicrobial Agents and Chemotherapy.
This study aimed to develop a population pharmacokinetic/pharmacodynamic (PK/PD) model of valganciclovir for preemptive therapy of cytomegalovirus (CMV) infection in kidney transplant patients. A population PK/PD model was developed with Monolix.
Publikováno v:
Infection Ecology & Epidemiology, Vol 5, Iss 0, Pp 1-6 (2015)
Background: Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae is an emerging therapeutic challenge, especially in the treatment of urinary tract infections. Following an outbreak of CTX-M-15 Klebsiella pneumoniae in Uppsala, Sweden
Externí odkaz:
https://doaj.org/article/8d1976a849a4481487dd021410366c59
Autor:
Elias Dahdouh, Lisa Allander, Linda Falgenhauer, Bogdan I. Iorga, Stefano Lorenzetti, Íñigo Marcos-Alcalde, Nathaniel I. Martin, Luis Martínez-Martínez, Jesús Mingorance, Thierry Naas, Joseph E. Rubin, Francesca Spyrakis, Thomas Tängdén, Paulino Gómez-Puertas
Publikováno v:
International Journal of Molecular Sciences, 23(17):9746. MDPI AG
The EPIC consortium brings together experts from a wide range of fields that include clinical, molecular and basic microbiology, infectious diseases, computational biology and chemistry, drug discovery and design, bioinformatics, biochemistry, biophy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a9bc342f51f20d60e52c00a58d6c2c
https://doi.org/10.3390/ijms23179746
https://doi.org/10.3390/ijms23179746