Good Research Practice in Non-Clinical Pharmacology and Biomedicine

Autor: Anton Bespalov, Martin C. Michel, Thomas Steckler

This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinica

PEERS — An Open Science 'Platform for the Exchange of Experimental Research Standards' in Biomedicine

Autor: Annesha Sil, Anton Bespalov, Christina Dalla, Chantelle Ferland-Beckham, Arnoud Herremans, Konstantinos Karantzalos, Martien J. Kas, Nikolaos Kokras, Michael J. Parnham, Pavlina Pavlidi, Kostis Pristouris, Thomas Steckler, Gernot Riedel, Christoph H. Emmerich

Publikováno v: Frontiers in Behavioral Neuroscience, Vol 15 (2021)

Laboratory workflows and preclinical models have become increasingly diverse and complex. Confronted with the dilemma of a multitude of information with ambiguous relevance for their specific experiments, scientists run the risk of overlooking critic

Externí odkaz: https://doaj.org/article/6fee03122d4f4e3b99d3b7135df1f208

Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0.

Autor: Nathalie Percie du Sert, Amrita Ahluwalia, Sabina Alam, Marc T Avey, Monya Baker, William J Browne, Alejandra Clark, Innes C Cuthill, Ulrich Dirnagl, Michael Emerson, Paul Garner, Stephen T Holgate, David W Howells, Viki Hurst, Natasha A Karp, Stanley E Lazic, Katie Lidster, Catriona J MacCallum, Malcolm Macleod, Esther J Pearl, Ole H Petersen, Frances Rawle, Penny Reynolds, Kieron Rooney, Emily S Sena, Shai D Silberberg, Thomas Steckler, Hanno Würbel

Publikováno v: PLoS Biology, Vol 18, Iss 7, p e3000411 (2020)

Improving the reproducibility of biomedical research is a major challenge. Transparent and accurate reporting is vital to this process; it allows readers to assess the reliability of the findings and repeat or build upon the work of other researchers

Externí odkaz: https://doaj.org/article/0cdc6121568245e7b56bd1cca7b31653

The EQIPD framework for rigor in the design, conduct, analysis and documentation of animal experiments

Autor: Jan, Vollert, Malcolm, Macleod, Ulrich, Dirnagl, Martien J, Kas, Martin C, Michel, Heidrun, Potschka, Gernot, Riedel, Kimberley E, Wever, Hanno, Würbel, Thomas, Steckler, Andrew S C, Rice

Publikováno v: Nature methods. 19(11)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::111d232e50546d416dbe14732198a6fc
https://pubmed.ncbi.nlm.nih.gov/36064774

Introduction to the EQIPD quality system

Autor: Lior Bikovski, Raafat Fares, Anton Bespalov, Claudia Kurreck, Leonardo Restivo, Paul Moser, Chantelle Ferland-Beckham, Claudia Stöger, Patricia Kabitzke, Ernesto Prado Montes de Oca, Bruce Altevogt, Valerie Gailus-Durner, Sabine M. Hölter, Piotr Popik, Martine C J Hofmann, Vootele Voikar, Lee Monk, Michael Schunn, Alexander Dityatev, Janko Samardzic, Gernot Riedel, Thomas Steckler, Natasja de Bruin, Merel Ritskes-Hoitinga, Kathleen Wuyts, Christoph H. Emmerich, Heidrun Potschka, Vincent Castagné, Christelle Froger-Colléaux, Fiona Ducrey, Anja Gilis, Björn Gerlach, Jan Vollert, Kimberley E. Wever, Sandrine Bongiovanni, Esmeralda Castaños-Vélez, Martien J H Kas, René Bernard, Malcolm R. Macleod, Isabel A Lefevre, Javier Guillén, Małgorzata Pietraszek, María Arroyo-Araujo, Ulrich Dirnagl

Publikováno v: Bespalov, A, Bernard, R, Gilis, A, Gerlach, B, Guillén, J, Castagné, V, Lefevre, I A, Ducrey, F, Monk, L, Bongiovanni, S, Altevogt, B, Arroyo-araujo, M, Bikovski, L, De Bruin, N, Castaños-vélez, E, Dityatev, A, Emmerich, C H, Fares, R, Ferland-beckham, C, Froger-colléaux, C, Gailus-durner, V, Hölter, S M, Hofmann, M C, Kabitzke, P, Kas, M J, Kurreck, C, Moser, P, Pietraszek, M, Popik, P, Potschka, H, Prado Montes De Oca, E, Restivo, L, Riedel, G, Ritskes-hoitinga, M, Samardzic, J, Schunn, M, Stöger, C, Voikar, V, Vollert, J, Wever, K E, Wuyts, K, Macleod, M R, Dirnagl, U & Steckler, T 2021, ' Introduction to the EQIPD quality system ', eLIFE, vol. 10 . https://doi.org/10.7554/eLife.63294
eLife, 10:e63294. ELIFE SCIENCES PUBLICATIONS LTD
eLife, Vol 10 (2021)
eLife 10, e63294 (2021). doi:10.7554/eLife.63294
eLife
Elife, 10
Bespalov, A, Bernard, R, Gilis, A, Gerlach, B, Guillén, J, Castagné, V, Lefevre, I A, Ducrey, F, Monk, L, Bongiovanni, S, Altevogt, B, Arroyo-Araujo, M, Bikovski, L, de Bruin, N, Castaños-Vélez, E, Dityatev, A, Emmerich, C H, Fares, R, Ferland-Beckham, C, Froger-Colléaux, C, Gailus-Durner, V, Hölter, S M, Hofmann, M C, Kabitzke, P, Kas, M J, Kurreck, C, Moser, P, Pietraszek, M, Popik, P, Potschka, H, Prado Montes de Oca, E, Restivo, L, Riedel, G, Ritskes-Hoitinga, M, Samardzic, J, Schunn, M, Stöger, C, Voikar, V, Vollert, J, Wever, K E, Wuyts, K, MacLeod, M R, Dirnagl, U & Steckler, T 2021, ' Introduction to the EQIPD quality system ', eLife, vol. 10, e63294 . https://doi.org/10.7554/eLife.63294
eLife, vol. 10, pp. e63294

While high risk of failure is an inherent part of developing innovative therapies, it can be reduced by adherence to evidence-based rigorous research practices. Numerous analyses conducted to date have clearly identified measures that need to be take

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aef7c0ead5b242adb59f95192215766
http://hdl.handle.net/10044/1/95909