Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Thomas, Severin"'
Autor:
Martin Metz, MD, Jonathan A. Bernstein, MD, Ana M. Giménez-Arnau, MD, PhD, Michihiro Hide, MD, PhD, Marcus Maurer, MD, Karl Sitz, MD, Weily Soong, MD, Gordon Sussman, MD, Eva Hua, MSc, Avantika Barve, PhD, Nathalie Barbier, MSc, Maria-Magdalena Balp, MD, Thomas Severin, MD
Publikováno v:
World Allergy Organization Journal, Vol 15, Iss 11, Pp 100716- (2022)
Background: Disease burden is particularly high in Chronic Spontaneous Urticaria (CSU) patients with angioedema, and patients whose signs and symptoms are inadequately controlled by H1-antihistamines need new treatment options. Here we report an expl
Externí odkaz:
https://doaj.org/article/a5accb64ff364949badf84c3169fe9b9
Autor:
Ana Giménez‐Arnau, Marcus Maurer, Jonathan Bernstein, Petra Staubach, Nathalie Barbier, Eva Hua, Thomas Severin, Yolandi Joubert, Reinhold Janocha, Maria‐Magdalena Balp
Publikováno v:
Clinical and Translational Allergy, Vol 12, Iss 2, Pp n/a-n/a (2022)
Abstract Background Chronic spontaneous urticaria (CSU) negatively impacts patients' sleep, thereby reducing health‐related quality of life (HRQoL). Half of patients with inadequately controlled CSU report sleep interference often or every night, w
Externí odkaz:
https://doaj.org/article/c654749ec2044c6fa71aef8c27a9caa8
Autor:
Jan Biegus, Biniyam Demissei, Douwe Postmus, Gad Cotter, Beth A. Davison, G. Michael Felker, Gerasimos Filippatos, Claudio Gimpelewicz, Barry Greenberg, Marco Metra, Thomas Severin, John R. Teerlink, Adriaan A. Voors, Piotr Ponikowski
Publikováno v:
ESC Heart Failure, Vol 6, Iss 6, Pp 1188-1198 (2019)
Abstract Aims Episodes of acute heart failure (AHF) may lead to end‐organ dysfunction. In this post hoc analysis of the Relaxin in Acute Heart Failure trial, we used the MELD‐XI (Model of End‐Stage Liver Dysfunction) score to examine hepatorena
Externí odkaz:
https://doaj.org/article/7c580ac554664da0ac31cd793ebef848
Autor:
Matteo Pagnesi, Marianna Adamo, Jozine M. ter Maaten, Iris E. Beldhuis, Gad Cotter, Beth A. Davison, G. Michael Felker, Gerasimos Filippatos, Barry H. Greenberg, Peter S. Pang, Piotr Ponikowski, Iziah E. Sama, Thomas Severin, Claudio Gimpelewicz, Adriaan A. Voors, John R. Teerlink, Marco Metra
Publikováno v:
European Journal of Heart Failure, 25(4), 541-552. Wiley
Aims: The impact of mitral regurgitation (MR) in patients hospitalized for acute heart failure (AHF) is not well established. We assessed the role of MR in patients enrolled in the Relaxin in Acute Heart Failure 2 (RELAX-AHF-2) trial. Methods and res
Autor:
Iziah E Sama, Beth A. Davison, Yuya Matsue, Peter S. Pang, Marco Metra, Gad Cotter, Claudio Gimpelewicz, Barry H. Greenberg, Gerasimos Filippatos, Douwe Postmus, Thomas Severin, Adriaan A. Voors, G. Michael Felker, Piotr Ponikowski, John R. Teerlink
Publikováno v:
JACC. Heart failure, 9(12), 890-903. ELSEVIER SCI LTD
OBJECTIVES: The aim of this study was to investigate the association between systolic blood pressure (SBP) drop, worsening renal function (WRF), and prognosis in patients with acute heart failure (AHF).BACKGROUND: A large drop in SBP early after hosp
Autor:
Maria-Magdalena Balp, Saoirse A Leonard, Thomas Severin, A Halliday, G Partha, A. Marsland, Manik Kalra
Publikováno v:
Dermatology and Therapy
Introduction Chronic spontaneous (previously known as idiopathic) urticaria (CSU) is a chronic skin disease with the potential for natural remission. The objectives of this targeted literature review were to identify evidence on the clinical course o
Autor:
Cristina Benito‐Villalvilla, Andrés de la Rocha‐Muñoz, Jacobo López‐Abente, Alexander Eggel, Iván Bottoli, Thomas Severin, Maximilian Woisetschläger, Oscar Palomares
Background Ligelizumab is an anti-IgE monoclonal antibody binding IgE with higher affinity than omalizumab that is under clinical investigation for several IgE-mediated diseases. We previously showed that omalizumab removes IgE bound to FcεRI on pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71836badbf1626bec99e45f97240959b
https://eprints.ucm.es/id/eprint/75657/
https://eprints.ucm.es/id/eprint/75657/
Autor:
Victoria K Snowdon, Neil J Lachlan, Anna M Hoy, Patrick W F Hadoke, Scott I Semple, Dilip Patel, Will Mungall, Timothy J Kendall, Adrian Thomson, Ross J Lennen, Maurits A Jansen, Carmel M Moran, Antonella Pellicoro, Prakash Ramachandran, Isaac Shaw, Rebecca L Aucott, Thomas Severin, Rajnish Saini, Judy Pak, Denise Yates, Neelesh Dongre, Jeremy S Duffield, David J Webb, John P Iredale, Peter C Hayes, Jonathan A Fallowfield
Publikováno v:
PLoS Medicine, Vol 14, Iss 2, p e1002248 (2017)
BackgroundChronic liver scarring from any cause leads to cirrhosis, portal hypertension, and a progressive decline in renal blood flow and renal function. Extreme renal vasoconstriction characterizes hepatorenal syndrome, a functional and potentially
Externí odkaz:
https://doaj.org/article/ab7417500a97421588c9af8b777a3c6d
Autor:
Sinisa Savic, I V Danilycheva, Alis Burciu, Avantika Barve, Ana Giménez-Arnau, Petra Staubach, Karl Sitz, Thomas Severin, Chia-Yu Chu, Michael Makris, Gordon Sussman, Jonathan A. Bernstein, Martin Metz, Marcus Maurer, Michihiro Hide, Eva Hua, Reinhold Janocha, Weily Soong
Background: Ligelizumab, a next-generation, humanized anti-immunoglobulin E (IgE) monoclonal antibody is in development as a treatment for patients with chronic spontaneous urticaria, whose symptoms are inadequately controlled with standard-of-care t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23593f71df398bcdf2c73e22822a6a4
Autor:
Irina Pivneva, Maria-Magdalena Balp, Yvonne Geissbühler, Thomas Severin, Serge Smeets, James Signorovitch, Jimmy Royer, Yawen Liang, Tom Cornwall, Jutong Pan, Andrii Danyliv, Sarah Jane McKenna, Alexander M. Marsland, Weily Soong
Publikováno v:
Dermatology and therapy. 12(12)
The time required to reach clinical remission varies in patients with chronic urticaria (CU). The objective of this study is to develop a predictive model using a machine learning methodology to predict time to clinical remission for patients with CU