Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Thomas, Renette"'
Publikováno v:
Molecular Pharmaceutics. 13:134-143
Efficient delivery of functional nucleic acids into specific cells or tissues is still a challenge for gene therapy and largely depends on targeted delivery strategies. The folate receptor (FR) is known to be overexpressed extracellularly on a variet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63953e307f10177bd16ac687a49356ef
https://doi.org/10.1021/acs.molpharmaceut.5b00575
https://doi.org/10.1021/acs.molpharmaceut.5b00575
Autor:
Olivia M. Merkel, Moritz Beck-Broichsitter, Nadja Bege, Damiano Librizzi, Thomas Kissel, Thomas Renette, Catherine Curdy, Thomas Endres, Holger Petersen
Publikováno v:
Macromolecular Bioscience. 12:970-978
The aim of this study is to investigate the feasibility and efficacy of PEC nanoparticles as delivery system for cancer chemotherapy. Assembly of paclitaxel-loaded nanoparticles with high loading efficiency and narrow-size distribution is successful.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a2a0830ce4b8b3cb9a44c5750806de7
https://doi.org/10.1002/mabi.201100499
https://doi.org/10.1002/mabi.201100499
Publikováno v:
Biomaterials. 32:7721-7731
Amphiphilic PEG-PCL-PEI triblock copolymers self-assemble into nano-scaled, positively charged, multifunctional carriers, suitable for drug and gene delivery. A set of block copolymers with varying hydrophilic/hydrophobic ratio (systematically altere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f69dc6aa6c8e9a28aabaaf875fe95b8
https://doi.org/10.1016/j.biomaterials.2011.06.064
https://doi.org/10.1016/j.biomaterials.2011.06.064
Autor:
Holger Petersen, Thomas Kissel, Rainer H. Müller, Thomas Renette, Mirko Jansch, Nadja Bege, Olivia M. Merkel, Regina Reul, Catherine Curdy
Publikováno v:
Macromolecular Bioscience. 11:897-904
The goal of this study was to investigate the suitability of poly(ethylene carbonate) (PEC) nanoparticles as a novel drug delivery system, fulfilling the requirements for a long circulation time. Particles were obtained with a narrow size distributio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6960e4cc66a91a80e37e803020f4a67
https://doi.org/10.1002/mabi.201000496
https://doi.org/10.1002/mabi.201000496
Publikováno v:
International Journal of Pharmaceutics. 407:190-196
The aim of this study was to formulate nanoparticles from three different hyperbranched polymers, namely an unmodified dendritic polyester (Boltorn H40™), a lipophilic, fatty acid modified dendritic polymer (Boltorn U3000™) and an amphiphilic den
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ad06ce38e58fccb4d28b8ef966e29af
https://doi.org/10.1016/j.ijpharm.2011.01.028
https://doi.org/10.1016/j.ijpharm.2011.01.028
Publikováno v:
Bioconjugate chemistry. 23(6)
Folate receptor (FR) is overexpressed in a variety of human cancers. Gene delivery vectors conjugated with folate as a ligand could possibly deliver gene materials into target tumor cells via FR-mediated endocytosis. This study addresses novel folate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd3dfc67c24eefa24ff2447341048a9
https://pubmed.ncbi.nlm.nih.gov/22548308
https://pubmed.ncbi.nlm.nih.gov/22548308
Autor:
Thomas, Renette, Damiano, Librizzi, Thomas, Endres, Olivia, Merkel, Moritz, Beck-Broichsitter, Nadja, Bege, Holger, Petersen, Catherine, Curdy, Thomas, Kissel
Publikováno v:
Macromolecular bioscience. 12(7)
The aim of this study is to investigate the feasibility and efficacy of PEC nanoparticles as delivery system for cancer chemotherapy. Assembly of paclitaxel-loaded nanoparticles with high loading efficiency and narrow-size distribution is successful.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ea334ea21b014f5eb68e3b8c611a73c0
https://pubmed.ncbi.nlm.nih.gov/22648959
https://pubmed.ncbi.nlm.nih.gov/22648959
Autor:
Daniel Hänggi, Thomas Kissel, Thomas Renette, Nadja Bege, Thomas Endres, Moritz Beck-Broichsitter
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 84(1)
The present study was conducted to examine the feasibility of nimodipine-loaded PLGA microparticles suspended in Tisseel fibrin sealant as an in situ forming depot system. This device locally placed can be used for the treatment of vasospasm after a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d298c98b5de9e758fb5891bcaaa455e7
https://pubmed.ncbi.nlm.nih.gov/23298622
https://pubmed.ncbi.nlm.nih.gov/23298622
Autor:
Nadja, Bege, Thomas, Renette, Mirko, Jansch, Regina, Reul, Olivia, Merkel, Holger, Petersen, Catherine, Curdy, Rainer H, Müller, Thomas, Kissel
Publikováno v:
Macromolecular bioscience. 11(7)
The goal of this study was to investigate the suitability of poly(ethylene carbonate) (PEC) nanoparticles as a novel drug delivery system, fulfilling the requirements for a long circulation time. Particles were obtained with a narrow size distributio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::56fb1b5e4e2e5a7c542b80da34e3bf70
https://pubmed.ncbi.nlm.nih.gov/21472988
https://pubmed.ncbi.nlm.nih.gov/21472988