Zobrazeno 1 - 10
of 243
pro vyhledávání: '"Thomas, Reiner"'
Autor:
Tami Yap, Ivy Tan, Rishi S. Ramani, Nirav Bhatia, Paula Demetrio de Souza Franca, Chris Angel, Caroline Moore, Thomas Reiner, Lindsay Bussau, Michael J. McCullough
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionScanned fibre endomicroscopes are full point-scanning confocal microscopes with submicron lateral resolution with an optical slice thickness thin enough to isolate individual cell layers, allow active positioning of the optical slice in t
Externí odkaz:
https://doaj.org/article/8c035b8d03374330b467195325daaea4
Autor:
Yohana C. Toner, Adam A. Ghotbi, Sonum Naidu, Ken Sakurai, Mandy M. T. van Leent, Stefan Jordan, Farideh Ordikhani, Letizia Amadori, Alexandros Marios Sofias, Elizabeth L. Fisher, Alexander Maier, Nathaniel Sullivan, Jazz Munitz, Max L. Senders, Christian Mason, Thomas Reiner, Georgios Soultanidis, Jason M. Tarkin, James H. F. Rudd, Chiara Giannarelli, Jordi Ochando, Carlos Pérez-Medina, Andreas Kjaer, Willem J. M. Mulder, Zahi A. Fayad, Claudia Calcagno
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract In recent years, cardiovascular immuno-imaging by positron emission tomography (PET) has undergone tremendous progress in preclinical settings. Clinically, two approved PET tracers hold great potential for inflammation imaging in cardiovascu
Externí odkaz:
https://doaj.org/article/fa3ab96dbfaf460a95866d8ed9e9732b
Autor:
Junior Gonzales, Giacomo Pirovano, Chun Yuen Chow, Paula Demetrio de Souza Franca, Lukas M. Carter, Julie K. Klint, Navjot Guru, Jason S. Lewis, Glenn F. King, Thomas Reiner
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-8 (2020)
Abstract Background Accidental peripheral nerve injury during surgical intervention results in a broad spectrum of potentially debilitating side effects. Tissue distortion and poor visibility can significantly increase the risk of nerve injury with l
Externí odkaz:
https://doaj.org/article/88cb7901fe984b199220e9001de5571c
Autor:
Navjot Guru, Paula Demétrio De Souza França, Giacomo Pirovano, Cien Huang, Snehal G. Patel, Thomas Reiner
Publikováno v:
Molecular Imaging, Vol 2021 (2021)
Background. Human papillomavirus- (HPV-) associated oropharyngeal squamous cell carcinomas (OPSCCs) are clinically and pathologically distinct from HPV-negative tumors. Here, we explore whether HPV affects functional biomarkers, including γH2AX, RAD
Externí odkaz:
https://doaj.org/article/345caf3642574dcd81c2a0e72746fd77
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Poly(ADP-ribose)polymerase-1 (PARP1) is a DNA repair enzyme highly expressed in the nuclei of mammalian cells, with a structure and function that have attracted interest since its discovery. PARP inhibitors, moreover, can be used to induce synthetic
Externí odkaz:
https://doaj.org/article/cc5af923006348f2a7dc040330feceab
Autor:
Christian Brand, Ahmad Sadique, Jacob L. Houghton, Kishore Gangangari, Jose F. Ponte, Jason S. Lewis, Naga Vara Kishore Pillarsetty, Jason A. Konner, Thomas Reiner
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Background The folate receptor α (FRα)-targeting antibody-drug conjugate (ADC), IMGN853, shows great antitumor activity against FRα-expressing tumors in vivo, but patient selection and consequently therapy outcome are based on immunohisto
Externí odkaz:
https://doaj.org/article/48194ca7f8f946429f00bb484510caba
Autor:
Patrick L. Donabedian, Susanne Kossatz, John A. Engelbach, Stephen A. Jannetti, Brandon Carney, Robert J. Young, Wolfgang A. Weber, Joel R. Garbow, Thomas Reiner
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Background Radiation injury can be indistinguishable from recurrent tumor on standard imaging. Current protocols for this differential diagnosis require one or more follow-up imaging studies, long dynamic acquisitions, or complex image post-
Externí odkaz:
https://doaj.org/article/3f947d958e0241a2a07b1ad001ca3df4
Autor:
Brandon Carney, Susanne Kossatz, Benjamin H. Lok, Valentina Schneeberger, Kishore K. Gangangari, Naga Vara Kishore Pillarsetty, Wolfgang A. Weber, Charles M. Rudin, John T. Poirier, Thomas Reiner
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Treatment of small-cell lung cancer remains a challenge due to multiple mechanisms of resistance to current therapies; measuring patient response is crucial in adapting and choosing adequate treatment. Here the authors develop a strategy to visualise
Externí odkaz:
https://doaj.org/article/e625a8f0d4ae4e3f93d027d2afb43df5
Publikováno v:
Photoacoustics, Vol 6, Iss C, Pp 1-8 (2017)
Optoacoustic imaging is a rapidly expanding field for the diagnosis, characterization, and treatment evaluation of cancer. However, the availability of tumor specific exogenous contrast agents is still limited. Here, we report on a small targeted con
Externí odkaz:
https://doaj.org/article/b5cb83c4951e46d397860aefaa3a18e2
Autor:
Edmund J. Keliher, Yu-Xiang Ye, Gregory R. Wojtkiewicz, Aaron D. Aguirre, Benoit Tricot, Max L. Senders, Hannah Groenen, Francois Fay, Carlos Perez-Medina, Claudia Calcagno, Giuseppe Carlucci, Thomas Reiner, Yuan Sun, Gabriel Courties, Yoshiko Iwamoto, Hye-Yeong Kim, Cuihua Wang, John W. Chen, Filip K. Swirski, Hsiao-Ying Wey, Jacob Hooker, Zahi A. Fayad, Willem J. M. Mulder, Ralph Weissleder, Matthias Nahrendorf
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
In vivo imaging of inflammation is crucial for detection and monitoring of many pathologies and noninvasive macrophage quantification has been suggested as a possible approach. Here Keliher et al. describe novel polyglucose nanoparticle tracers that
Externí odkaz:
https://doaj.org/article/a325edd59ddf4dab8474aa0b334a7eea