Common variants in breast cancer risk loci predispose to distinct tumor subtypes

Autor: Thomas U. Ahearn, Haoyu Zhang, Kyriaki Michailidou, Roger L. Milne, Manjeet K. Bolla, Joe Dennis, Alison M. Dunning, Michael Lush, Qin Wang, Irene L. Andrulis, Hoda Anton-Culver, Volker Arndt, Kristan J. Aronson, Paul L. Auer, Annelie Augustinsson, Adinda Baten, Heiko Becher, Sabine Behrens, Javier Benitez, Marina Bermisheva, Carl Blomqvist, Stig E. Bojesen, Bernardo Bonanni, Anne-Lise Børresen-Dale, Hiltrud Brauch, Hermann Brenner, Angela Brooks-Wilson, Thomas Brüning, Barbara Burwinkel, Saundra S. Buys, Federico Canzian, Jose E. Castelao, Jenny Chang-Claude, Stephen J. Chanock, Georgia Chenevix-Trench, Christine L. Clarke, NBCS Collaborators, J. Margriet Collée, Angela Cox, Simon S. Cross, Kamila Czene, Mary B. Daly, Peter Devilee, Thilo Dörk, Miriam Dwek, Diana M. Eccles, D. Gareth Evans, Peter A. Fasching, Jonine Figueroa, Giuseppe Floris, Manuela Gago-Dominguez, Susan M. Gapstur, José A. García-Sáenz, Mia M. Gaudet, Graham G. Giles, Mark S. Goldberg, Anna González-Neira, Grethe I. Grenaker Alnæs, Mervi Grip, Pascal Guénel, Christopher A. Haiman, Per Hall, Ute Hamann, Elaine F. Harkness, Bernadette A. M. Heemskerk-Gerritsen, Bernd Holleczek, Antoinette Hollestelle, Maartje J. Hooning, Robert N. Hoover, John L. Hopper, Anthony Howell, ABCTB Investigators, kConFab/AOCS Investigators, Milena Jakimovska, Anna Jakubowska, Esther M. John, Michael E. Jones, Audrey Jung, Rudolf Kaaks, Saila Kauppila, Renske Keeman, Elza Khusnutdinova, Cari M. Kitahara, Yon-Dschun Ko, Stella Koutros, Vessela N. Kristensen, Ute Krüger, Katerina Kubelka-Sabit, Allison W. Kurian, Kyriacos Kyriacou, Diether Lambrechts, Derrick G. Lee, Annika Lindblom, Martha Linet, Jolanta Lissowska, Ana Llaneza, Wing-Yee Lo, Robert J. MacInnis, Arto Mannermaa, Mehdi Manoochehri, Sara Margolin, Maria Elena Martinez, Catriona McLean, Alfons Meindl, Usha Menon, Heli Nevanlinna, William G. Newman, Jesse Nodora, Kenneth Offit, Håkan Olsson, Nick Orr, Tjoung-Won Park-Simon, Alpa V. Patel, Julian Peto, Guillermo Pita, Dijana Plaseska-Karanfilska, Ross Prentice, Kevin Punie, Katri Pylkäs, Paolo Radice, Gad Rennert, Atocha Romero, Thomas Rüdiger, Emmanouil Saloustros, Sarah Sampson, Dale P. Sandler, Elinor J. Sawyer, Rita K. Schmutzler, Minouk J. Schoemaker, Ben Schöttker, Mark E. Sherman, Xiao-Ou Shu, Snezhana Smichkoska, Melissa C. Southey, John J. Spinelli, Anthony J. Swerdlow, Rulla M. Tamimi, William J. Tapper, Jack A. Taylor, Lauren R. Teras, Mary Beth Terry, Diana Torres, Melissa A. Troester, Celine M. Vachon, Carolien H. M. van Deurzen, Elke M. van Veen, Philippe Wagner, Clarice R. Weinberg, Camilla Wendt, Jelle Wesseling, Robert Winqvist, Alicja Wolk, Xiaohong R. Yang, Wei Zheng, Fergus J. Couch, Jacques Simard, Peter Kraft, Douglas F. Easton, Paul D. P. Pharoah, Marjanka K. Schmidt, Montserrat García-Closas, Nilanjan Chatterjee

Publikováno v: Breast Cancer Research, Vol 24, Iss 1, Pp 1-13 (2022)

Abstract Background Genome-wide association studies (GWAS) have identified multiple common breast cancer susceptibility variants. Many of these variants have differential associations by estrogen receptor (ER) status, but how these variants relate wi

Externí odkaz: https://doaj.org/article/cae5eda371db4a06b0f026b1ac32a25f

Automatisierung und der Einsatz von Robotern im Pathologielabor

Autor: Hermann Herbst, Thomas Rüdiger

Publikováno v: Die Pathologie. 43:56-63

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6db762547834b18ac7f9ff6fec5311aa
https://doi.org/10.1007/s00292-022-01157-2

Supplemental Methods, Figures 1-2, Table S1 from Standardized Ki67 Diagnostics Using Automated Scoring—Clinical Validation in the GeparTrio Breast Cancer Study

Autor: Gunter von Minckwitz, Carsten Denkert, Manfred Dietel, Bianca Lederer, Keyur Mehta, Erhard Erbstößer, Thomas Rüdiger, Jens Huober, Jens-Uwe Blohmer, Bernd Gerber, Sibylle Loibl, Wolfgang D. Schmitt, Stephan Wienert, Frederick Klauschen

Supplemental Methods, Figures 1-2, Table S1. Supplemental Methods providing details on the study cohort and the image analysis algorithm. Supp. Figure 1: A) Ki67 stained breast cancer tissue. B) Haematoxylin Signal derived from color deconvolution (1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::819608def8dccf10aa46043c78c34421
https://doi.org/10.1158/1078-0432.22457844.v1

Data from Ki67 Measured after Neoadjuvant Chemotherapy for Primary Breast Cancer

Autor: Carsten Denkert, Christian Jackisch, Volkmar Müller, Thomas Karn, Peter A. Fasching, Erhard Erbstoesser, Thomas Rüdiger, Jana Barinoff, Tanja Fehm, Jens Huober, Jörn Hilfrich, Hans Tesch, Bernd Gerber, Wolfgang Eiermann, Holger Eidtmann, Bruno V. Sinn, Jens U. Blohmer, Berit M. Müller, Sibylle Loibl, Wolfgang D. Schmitt, Gunter von Minckwitz

Purpose: The value of Ki67 measured on residual disease after neoadjuvant chemotherapy is not sufficiently described.Experimental Design: Participants of the GeparTrio study with primary breast cancer randomly received neoadjuvant response-guided [8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2924045e06044bbf75c2b04c54ad78cd
https://doi.org/10.1158/1078-0432.c.6521144

Supplementary Table 1 from Chromosomal Breakpoints Affecting Immunoglobulin Loci Are Recurrent in Hodgkin and Reed-Sternberg Cells of Classical Hodgkin Lymphoma

Autor: Reiner Siebert, Martin L. Hansmann, Ralf Küppers, Harald Stein, Thomas Rüdiger, Reza M. Parwaresch, Peter Möller, Irina B. Kaplanskaya, Georgiy A. Frank, Stefan Gesk, Alexander Claviez, Heinz-Wolfram Bernd, Françoise Berger, Thomas F.E. Barth, Jennifer Riemke, Jorge Höppner, Susanne Grohmann, Roland Schmitz, Christian Bastard, Lana Harder, Evelyne Callet-Bauchu, Anna Sotnikova, Wolfram Klapper, José I. Martín-Subero

Supplementary Table 1 from Chromosomal Breakpoints Affecting Immunoglobulin Loci Are Recurrent in Hodgkin and Reed-Sternberg Cells of Classical Hodgkin Lymphoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164fba31e496274ac87ed734c8952595
https://doi.org/10.1158/0008-5472.22365615