Long-axial field-of-view PET/CT: perspectives and review of a revolutionary development in nuclear medicine based on clinical experience in over 7000 patients

Autor: Ian Alberts, Hasan Sari, Clemens Mingels, Ali Afshar-Oromieh, Thomas Pyka, Kuangyu Shi, Axel Rominger

Publikováno v: Cancer Imaging, Vol 23, Iss 1, Pp 1-15 (2023)

Abstract Recently introduced long-axial field-of-view (LAFOV) PET/CT systems represent one of the most significant advancements in nuclear medicine since the advent of multi-modality PET/CT imaging. The higher sensitivity exhibited by such systems al

Externí odkaz: https://doaj.org/article/18d71ad1428946a88b1de47507793584

Multiparametric Characterization of Intracranial Gliomas Using Dynamic [18F]FET-PET and Magnetic Resonance Spectroscopy

Autor: Thomas Pyka, Iwona Krzyzanowska, Axel Rominger, Claire Delbridge, Bernhard Meyer, Tobias Boeckh-Behrens, Claus Zimmer, Jens Gempt

Publikováno v: Diagnostics, Vol 12, Iss 10, p 2331 (2022)

Both static and dynamic O-(2-[18F]fluoroethyl)-l-tyrosine-(FET)-PET and 1H magnetic resonance spectroscopy (MRS) are useful tools for grading and prognostication in gliomas. However, little is known about the potential of multimodal imaging comprisin

Externí odkaz: https://doaj.org/article/2e9fd5223d4f411fb85a1aaaf388abdf

Comparison of CT, MRI, and F-18 FDG PET/CT for initial N-staging of oral squamous cell carcinoma: a cost-effectiveness analysis

Autor: Egon Burian, Benjamin Palla, Nicholas Callahan, Thomas Pyka, Constantin Wolff, Claudio E. von Schacky, Annabelle Schmid, Matthias F. Froelich, Johannes Rübenthaler, Marcus R. Makowski, Felix G. Gassert

Publikováno v: Burian, Egon; Palla, Benjamin; Callahan, Nicholas; Pyka, Thomas; Wolff, Constantin; von Schacky, Claudio E; Schmid, Annabelle; Froelich, Matthias F; Rübenthaler, Johannes; Makowski, Marcus R; Gassert, Felix G (2022). Comparison of CT, MRI, and F-18 FDG PET/CT for initial N-staging of oral squamous cell carcinoma: a cost-effectiveness analysis. European journal of nuclear medicine and molecular imaging, 49(11), pp. 3870-3877. Springer 10.1007/s00259-022-05843-4

Background and purpose Treatment of oral squamous cell carcinoma (OSCC) is based on clinical exam, biopsy, and a precise imaging-based TNM-evaluation. A high sensitivity and specificity for magnetic resonance imaging (MRI) and F-18 FDG PET/CT are rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d0624f460bf28ff8db256a2a2cde3b
https://doi.org/10.1007/s00259-022-05843-4

Textural features in FDG-PET/CT can predict outcome in melanoma patients to treatment with Vemurafenib and Ipililumab

Autor: Daniela Dittrich, Ralph A. Bundschuh, Thomas Pyka, Markus Essler, Susanne Lütje, K Scheidhauer

Publikováno v: Nuklearmedizin. 59:228-234

Aim Recently, textural parameters assessed in FDG-PET/CT as surrogate marker for tumor heterogeneity have been shown to provide prognostic power. Therefore, we investigated the use of such parameters in FDG-PET/CT examinations before the start of imm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e886fb0fe48c80b146b35b22d417b6
https://doi.org/10.1055/a-1140-5458

Consistency of normalized cerebral blood volume values in glioblastoma using different leakage correction algorithms on dynamic susceptibility contrast magnetic resonance imaging data without and with preload

Autor: Benedikt Wiestler, Thomas Pyka, Christine Preibisch, Anne Kluge, Jan S. Kirschke, Dennis M. Hedderich, Claus Zimmer

Publikováno v: Journal of Neuroradiology. 46:44-51

Background and purpose Several leakage correction algorithms for dynamic susceptibility contrast (DSC) magnetic resonance imaging (MRI)-based cerebral blood volume (CBV) measurement have been proposed, and combination with a preload of contrast agent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff51e0973ac6eb665c803e529c416310
https://doi.org/10.1016/j.neurad.2018.04.006