Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Thomas, Penz"'
Autor:
André F. Rendeiro, Thomas Krausgruber, Nikolaus Fortelny, Fangwen Zhao, Thomas Penz, Matthias Farlik, Linda C. Schuster, Amelie Nemc, Szabolcs Tasnády, Marienn Réti, Zoltán Mátrai, Donát Alpár, Csaba Bödör, Christian Schmidl, Christoph Bock
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Ibrutinib, a Bruton tyrosine kinase inhibitor, provides effective treatment for chronic lymphocytic leukemia (CLL). Here, the authors describe time-dependent molecular changes to malignant cells and to the immune system in patients undergoing ibrutin
Externí odkaz:
https://doaj.org/article/73b869eadff94edea5bfbf6a4cfbce75
Autor:
Tamara Casteels, Yufeng Zhang, Thomas Frogne, Caterina Sturtzel, Charles-Hugues Lardeau, Ilke Sen, Xiaocheng Liu, Shangyu Hong, Florian M. Pauler, Thomas Penz, Marlene Brandstetter, Charlotte Barbieux, Ekaterine Berishvili, Thomas Heuser, Christoph Bock, Christian G. Riedel, Dirk Meyer, Martin Distel, Jacob Hecksher-Sørensen, Jin Li, Stefan Kubicek
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101329- (2021)
Objective: The loss of forkhead box protein O1 (FoxO1) signaling in response to metabolic stress contributes to the etiology of type II diabetes, causing the dedifferentiation of pancreatic beta cells to a cell type reminiscent of endocrine progenito
Externí odkaz:
https://doaj.org/article/a0e438a3cef045b6a78157d78619e54d
Autor:
Jasmina Panovska-Griffiths, Chris Griffiths, Andrea Siebenhofer, Christoph Bock, Werner Leber, Karin Stiasny, Oliver Lammel, Monika Redlberger-Fritz, Maria Elisabeth Mustafa-Korninger, Reingard Christina Glehr, Jeremy Camp, Benedikt Agerer, Alexander Lercher, Alexandra Popa, Jakob-Wendelin Genger, Thomas Penz, Stephan Aberle, Andreas Bergthaler, Eva-Maria Hochstrasser, Christian Hoellinger
Publikováno v:
BMJ Open, Vol 11, Iss 8 (2021)
Objectives We explore the importance of SARS-CoV-2 sentinel surveillance testing in primary care during a regional COVID-19 outbreak in Austria.Design Prospective cohort study.Setting A single sentinel practice serving 22 829 people in the ski-resort
Externí odkaz:
https://doaj.org/article/e01625da1827485099aa773e68ed83e3
Autor:
Johannes Griss, Wolfgang Bauer, Christine Wagner, Martin Simon, Minyi Chen, Katharina Grabmeier-Pfistershammer, Margarita Maurer-Granofszky, Florian Roka, Thomas Penz, Christoph Bock, Gao Zhang, Meenhard Herlyn, Katharina Glatz, Heinz Läubli, Kirsten D. Mertz, Peter Petzelbauer, Thomas Wiesner, Markus Hartl, Winfried F. Pickl, Rajasekharan Somasundaram, Peter Steinberger, Stephan N. Wagner
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The regulation of tumor inflammation is incompletely understood and the role of B cells is unclear. Here, the authors show that a specific subtype of B cells is induced in melanoma and required to recruit T lymphocytes and elicit inflammation.
Externí odkaz:
https://doaj.org/article/bb7a13c9ab124182a8b518e472ddcec1
Autor:
Alexandra Franziska Gülich, Ramona Rica, Caroline Tizian, Csilla Viczenczova, Kseniya Khamina, Thomas Faux, Daniela Hainberger, Thomas Penz, Remy Bosselut, Christoph Bock, Asta Laiho, Laura L. Elo, Andreas Bergthaler, Wilfried Ellmeier, Shinya Sakaguchi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The BTB zinc finger transcription factor MAZR (also known as PATZ1) controls, partially in synergy with the transcription factor Runx3, the development of CD8 lineage T cells. Here we explored the role of MAZR as well as combined activities of MAZR/R
Externí odkaz:
https://doaj.org/article/4b233b2a316e48e78a3000b1d9d5c593
Autor:
Bianca V Gapp, Tomasz Konopka, Thomas Penz, Vineet Dalal, Tilmann Bürckstümmer, Christoph Bock, Sebastian MB Nijman
Publikováno v:
Molecular Systems Biology, Vol 12, Iss 8, Pp 1-9 (2016)
Abstract Reverse genetic screens have driven gene annotation and target discovery in model organisms. However, many disease‐relevant genotypes and phenotypes cannot be studied in lower organisms. It is therefore essential to overcome technical hurd
Externí odkaz:
https://doaj.org/article/d8ea184279a4405fb6d0eab253cd8844
Autor:
Lena König, Alexander Siegl, Thomas Penz, Susanne Haider, Cecilia Wentrup, Julia Polzin, Evelyne Mann, Stephan Schmitz-Esser, Daryl Domman, Matthias Horn
Publikováno v:
mSystems, Vol 2, Iss 3 (2017)
ABSTRACT Chlamydiae are obligate intracellular bacteria comprising well-known human pathogens and ubiquitous symbionts of protists, which are characterized by a unique developmental cycle. Here we comprehensively analyzed gene expression dynamics of
Externí odkaz:
https://doaj.org/article/906b3cb8ac4b45da8757cb8bde444f01
Autor:
Andreas Reinisch, Johannes Lorenz Berg, Gudrun Pregartner, Carsten Müller-Tidow, Klaus Geissler, Barbara Uhl, Andreas Prokesch, Albert Wölfler, Michael Schuster, Stefan Hatzl, Armin Zebisch, Bianca Perfler, Andrea Berghold, Thomas Penz, Heinz Sill, Veronica Caraffini, Gerald Hoefler, Karl Kashofer
Publikováno v:
Leukemia
Funder: MUG (within the PhD program Molecular Medicine)
Funder: Austrian Society of Internal Medicine (Joseph-Skoda Award), Austrian Science Fund (grant P32783), Austrian Society of Hematology and Medical Oncology (Clinical Research Grant) and M
Funder: Austrian Society of Internal Medicine (Joseph-Skoda Award), Austrian Science Fund (grant P32783), Austrian Society of Hematology and Medical Oncology (Clinical Research Grant) and M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b47365da0a57c7a66377c2b987474a
https://doi.org/10.1038/s41375-021-01161-0
https://doi.org/10.1038/s41375-021-01161-0
Autor:
Szabolcs Tasnády, Thomas Krausgruber, Donát Alpár, Nikolaus Fortelny, Amelie Nemc, Zoltán Mátrai, André F. Rendeiro, Christian Schmidl, Csaba Bödör, Marienn Réti, Matthias Farlik, Thomas Penz, Christoph Bock, Fangwen Zhao, Linda C. Schuster
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
The Bruton tyrosine kinase (BTK) inhibitor ibrutinib provides effective treatment for patients with chronic lymphocytic leukemia (CLL), despite extensive heterogeneity in this disease. To define the underlining regulatory dynamics, we analyze high-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a95e98a515de7437bb90e1b670201914
http://link.springer.com/article/10.1038/s41467-019-14081-6
http://link.springer.com/article/10.1038/s41467-019-14081-6
Autor:
Andreas Bergthaler, F. Amman, A. O. Wagner, Lukas Endler, Thomas Penz, R. Markt, H. Insam, Wolfgang Rauch, F. Allerberger, M. Mayr, D. Grünbacher, A. Schedl, M. Büchel-Marxer, M. Pedrazzini, E. Peer
Publikováno v:
Journal of Water and Health, Vol 20, Iss 1, Pp 114-125 (2022)
The new coronavirus 2 (SARS-CoV-2) is known to be also shed through feces, which makes wastewater-based surveillance possible, independent of symptomatic cases and unbiased by any testing strategies and frequencies. We investigated the entire populat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6441812d66d24c97b88a5b78d930315
https://pubmed.ncbi.nlm.nih.gov/35100159
https://pubmed.ncbi.nlm.nih.gov/35100159