Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Thomas, Lanza"'
Autor:
Richard L. Tolman, Susan Aster, Raman K. Bakshi, Jeffrey P. Bergman, Herb G. Bull, Benedict Chang, George Cimis, Michael P. Dolenga, Phillippe Durette, Kenneth Ellsworth, Craig Esser, Donald W. Graham, William K. Hagmann, Georgianna Harris, Ihor Kopka, Thomas Lanza, Gool Patel, Scott Polo, Gary H. Rasmusson, Soumya Sahoo, Jeffrey H. Toney, Derek Von Langen, Bruce Witzel
Publikováno v:
European Journal of Medicinal Chemistry. 30:311s-316s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdce1c65646d2979e6f48fc46946df19
https://doi.org/10.1016/s0223-5234(23)00132-0
https://doi.org/10.1016/s0223-5234(23)00132-0
Autor:
Linus S, Lin, Thomas, Lanza, James P, Jewell, Ping, Liu, Carrie, Jones, Gerard R, Kieczykowski, Kelly, Treonze, Qian, Si, Salony, Manior, Gloria, Koo, Xinchun, Tong, Junying, Wang, Anne, Schuelke, James, Pivnichny, Regina, Wang, Conrad, Raab, Stella, Vincent, Philip, Davies, Malcolm, Maccoss, Richard A, Mumford, William K, Hagmann
Publikováno v:
Journal of medicinal chemistry. 52(11)
Extremely potent very late antigen-4 (VLA-4) antagonists with picomolar, whole blood activity and slow dissociation rates were discovered by incorporating an amino substituent on the proline fragment of the initial lead structure. This level of poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9a6bbef5a020db297b6f1e1be61f223
https://pubmed.ncbi.nlm.nih.gov/19441819
https://pubmed.ncbi.nlm.nih.gov/19441819
Autor:
Linda A, Egger, Usha, Kidambi, Jin, Cao, Gail, Van Riper, Ermengilda, McCauley, Richard A, Mumford, Suzanne, Amo, Russell, Lingham, Thomas, Lanza, Linus S, Lin, Stephen E, De Laszlo, David N, Young, Ihor E, Kopka, Sharon, Tong, Bill, Pikounis, Evelyn, Benson, Sarah, Warwood, Robert F, Bargatze, William K, Hagmann, John A, Schmidt, Patricia A, Detmers
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 302(1)
The alpha(4) integrin, alpha(4)beta(7), plays an important role in recruiting circulating lymphocytes to the gastrointestinal tract, where its ligand mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is preferentially expressed on high endothelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ad044cb8bb9b9b193e230c559d1645b
https://pubmed.ncbi.nlm.nih.gov/12065712
https://pubmed.ncbi.nlm.nih.gov/12065712
Autor:
Linus S, Lin, Thomas, Lanza, Ermenegilda, McCauley, Gail, Van Riper, Usha, Kidambi, Jin, Cao, Linda A, Egger, Richard A, Mumford, John A, Schmidt, Malcolm, MacCoss, William K, Hagmann
Publikováno v:
Bioorganicmedicinal chemistry letters. 12(2)
N-(3,5-Dichlorophenylsulfonyl)-(R)-thioprolyl biarylalanine 10a has been identified as a potent and specific antagonist of the alpha(4)beta(1) integrin. Altering the configuration of thioproline from R to S led to a series of dual antagonists of alph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b6792c29bd570b8392c998169bd4d28
https://pubmed.ncbi.nlm.nih.gov/11755338
https://pubmed.ncbi.nlm.nih.gov/11755338
Autor:
Linus S. Lin, Thomas Lanza, James P. Jewell, Ping Liu, Carrie Jones, Gerard R. Kieczykowski, Kelly Treonze, Qian Si, Salony Manior, Gloria Koo, Xinchun Tong, Junying Wang, Anne Schuelke, James Pivnichny, Regina Wang, Conrad Raab, Stella Vincent, Philip Davies, Malcolm MacCoss, Richard A. Mumford
Publikováno v:
Journal of Medicinal Chemistry; Jun2009, Vol. 52 Issue 11, p3449-3452, 4p
Autor:
A, Egger Linda, Usha, Kidambi, Jin, Cao, Gail, Van Riper, Ermengilda, McCauley, A, Mumford Richard, Suzanne, Amo, Russell, Lingham, Thomas, Lanza, S, Lin Linus, E, De Laszlo Stephen, N, Young David, E, Kopka Ihor, Sharon, Tong, Bill, Pikounis, Evelyn, Benson, Sarah, Warwood, F, Bargatze Robert, K, Hagmann William, A, Schmidt John, A, Detmers Patricia
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics; July 2002, Vol. 302 Issue: 1 p153-62, 10p