Spatial tumour gene signature discriminates neoplastic from non-neoplastic compartments in colon cancer: unravelling predictive biomarkers for relapse

Autor: Katja Sallinger, Michael Gruber, Christin-Therese Müller, Lilli Bonstingl, Elisabeth Pritz, Karin Pankratz, Armin Gerger, Maria Anna Smolle, Ariane Aigelsreiter, Olga Surova, Jessica Svedlund, Mats Nilsson, Thomas Kroneis, Amin El-Heliebi

Publikováno v: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-14 (2023)

Abstract Background Opting for or against the administration of adjuvant chemotherapy in therapeutic management of stage II colon cancer remains challenging. Several studies report few survival benefits for patients treated with adjuvant therapy and

Externí odkaz: https://doaj.org/article/d49387f319bf4f0199754c5da523007e

Disturbed trophoblast transition links preeclampsia progression from placenta to the maternal syndrome

Autor: Olivia Nonn, Olivia Debnath, Daniela S. Valdes, Katja Sallinger, Ali Kerim Secener, Sandra Haider, Cornelius Fischer, Sebastian Tiesmeyer, Jose Nimo, Thomas Kuenzer, Theresa Maxian, Martin Knöfler, Philipp Karau, Hendrik Bartolomaeus, Thomas Kroneis, Alina Frolova, Lena Neuper, Nadine Haase, Kristin Kräker, Sarah Kedziora, Désirée Forstner, Stefan Verlohren, Christina Stern, Fabian Coscia, Meryam Sugulle, Stuart Jones, Basky Tilaganathan, Roland Eils, Berthold Huppertz, Amin El-Heliebi, Anne Cathrine Staff, Dominik N. Müller, Ralf Dechend, Martin Gauster, Naveed Ishaque, Florian Herse

SummaryPre-eclampsia (PE) is a syndrome that affects multiple organ systems and is the most severe hypertensive disorder in pregnancy. It frequently leads to preterm delivery, maternal and fetal morbidity and mortality and life-long complications1. W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cfb6c155babf5b680ffc59d43d322b58
https://doi.org/10.1101/2022.10.10.511539

Sperm in the implantation-stage blastocyst: Is it a check point of embryo quality?

Autor: Berthold Huppertz, Jayasree Sengupta, Thomas Kroneis, Amy Boddy, Rahul Roy, Anish Sarkar, Deepayan Sarkar, Debabrata Ghosh

The early human embryo derived from fusion of an oocyte with a single sperm undergoes growth and differentiation and results in an implantation-ready blastocyst. To initiate implantation, the blastocyst hatches from the zona pellucida, thus making it

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f095e7b87603888124751d5bfe2a03a3
https://doi.org/10.21203/rs.3.rs-1997747/v1

EXTH-04. PATIENT-DERIVED CELLS FOR EX VIVO DRUG SCREENING STUDIES OF GLIOMAS

Autor: Amin El-Heliebi, Tadeja Urbanic-Purkart, Kariem Mahdy-Ali, Christina Skofler, Lisa Gerlitz, Stefanie Stanzer, Joakim Franz, Nora Harbusch, Tobias Madl, Georg Widhalm, Karl Rössler, Martina Tomberger, Karin Mattersdorfer, Thomas Kroneis, Monika Oberhuber, Thomas Pieber, Barbara Prietl

Publikováno v: Neuro-Oncology. 24:vii209-vii209

BACKGROUND In precision oncology ex vivo drug screening systems have the potential to improve clinical outcomes. Traditionally, cancer drugs are tested on cancer cell line models, but these cannot represent an individual patient and are biologically

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https://doi.org/10.1093/neuonc/noac209.803

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

Autor: Lara Gibellini, Sussan Nourshargh, Susanna Cardell, Wlodzimierz Maslinski, Mar Felipo-Benavent, Florian Mair, Hans-Martin Jäck, Lilly Lopez, Klaus Warnatz, John Trowsdale, Diana Ordonez, Marcus Eich, William Hwang, Anne Cooke, Dirk Mielenz, Alberto Orfao, Winfried F. Pickl, Vladimir Benes, Alice Yue, T. Vincent Shankey, Maria Tsoumakidou, Virginia Litwin, Gelo Victoriano Dela Cruz, Andrea Cavani, Sara De Biasi, Larissa Nogueira Almeida, Jonathan J M Landry, Claudia Haftmann, Charlotte Esser, Ana Cumano, Anneke Wilharm, Francesco Dieli, Rudi Beyaert, Alessio Mazzoni, Burkhard Ludewig, Carlo Pucillo, Dirk H. Busch, Joe Trotter, Stipan Jonjić, Marc Veldhoen, Josef Spidlen, Aja M. Rieger, Dieter Adam, Srijit Khan, Todd A. Fehniger, Giuseppe Matarese, Maximilien Evrard, Christian Maueröder, Steffen Schmitt, Kristin A. Hogquist, Barry Moran, Raghavendra Palankar, Markus Feuerer, S Schmid, Susann Rahmig, Amy E. Lovett-Racke, James V. Watson, Megan K. Levings, Susanne Melzer, Dinko Pavlinic, Christopher M. Harpur, Christina Stehle, A. Graham Pockley, Toshinori Nakayama, Attila Tárnok, Juhao Yang, Michael Lohoff, Paulo Vieira, Francisco Sala-de-Oyanguren, Christian Kurts, Anastasia Gangaev, Alfonso Blanco, Hans Scherer, Regine J. Dress, Bruno Silva-Santos, Kiyoshi Takeda, Bimba F. Hoyer, Ilenia Cammarata, Daryl Grummitt, Isabel Panse, Günnur Deniz, Bianka Baying, Friederike Ebner, Esther Schimisky, Leo Hansmann, Thomas Kamradt, Edwin van der Pol, Daniel Scott-Algara, Anna Iannone, Giorgia Alvisi, Sebastian R. Schulz, Francesco Liotta, Irmgard Förster, Beatriz Jávega, Hans-Peter Rahn, Caetano Reis e Sousa, Livius Penter, Xuetao Cao, David P. Sester, Keisuke Goda, Peter Wurst, Iain B. McInnes, Ricardo T. Gazzinelli, Federica Piancone, Gerald Willimsky, Yotam Raz, Pärt Peterson, Wolfgang Fritzsche, Yvonne Samstag, Martin Büscher, Thomas Schüler, Susanne Hartmann, Robert J. Wilkinson, Anna E. S. Brooks, Steven L. C. Ketelaars, Catherine Sautès-Fridman, Anna Rubartelli, Petra Bacher, Katja Kobow, Marco A. Cassatella, Andrea Hauser, Henrik E. Mei, Kilian Schober, Silvia Della Bella, Graham Anderson, Michael D. Ward, Garth Cameron, Sebastian Lunemann, Katharina Kriegsmann, Katarzyna M. Sitnik, Brice Gaudilliere, Chantip Dang-Heine, Marcello Pinti, Paul Klenerman, Frank A. Schildberg, Joana Barros-Martins, Laura G. Rico, Hanlin Zhang, Christian Münz, Thomas Dörner, Jakob Zimmermann, Andrea M. Cooper, Jonni S. Moore, Andreas Diefenbach, Yanling Liu, Wolfgang Bauer, Tobit Steinmetz, Katharina Pracht, Leonard Tan, Peter K. Jani, Alan M. Stall, Petra Hoffmann, Christine S. Falk, Jasmin Knopf, Simon Fillatreau, Hans-Dieter Volk, Luis E. Muñoz, David L. Haviland, William W. Agace, Jonathan Rebhahn, Ljiljana Cvetkovic, Mohamed Trebak, Jordi Petriz, Mario Clerici, Diether J. Recktenwald, Anders Ståhlberg, Tristan Holland, Helen M. McGuire, Sa A. Wang, Christian Kukat, Thomas Kroneis, Laura Cook, Wan Ting Kong, Xin M. Wang, Britta Engelhardt, Pierre Coulie, Genny Del Zotto, Sally A. Quataert, Kata Filkor, Gabriele Multhoff, Bartek Rajwa, Federica Calzetti, Hans Minderman, Cosima T. Baldari, Jens Geginat, Hervé Luche, Gert Van Isterdael, Linda Schadt, Sophia Urbanczyk, Giovanna Borsellino, Liping Yu, Dale I. Godfrey, Achille Anselmo, Rachael C. Walker, Andreas Grützkau, David W. Hedley, Birgit Sawitzki, Silvia Piconese, Maria Yazdanbakhsh, Burkhard Becher, Ramon Bellmas Sanz, Michael Delacher, Hyun-Dong Chang, Immanuel Andrä, Hans-Gustaf Ljunggren, José-Enrique O'Connor, Ahad Khalilnezhad, Sharon Sanderson, Federico Colombo, Götz R. A. Ehrhardt, Inga Sandrock, Enrico Lugli, Christian Bogdan, James B. Wing, Susann Müller, Tomohiro Kurosaki, Derek Davies, Ester B. M. Remmerswaal, Kylie M. Quinn, Christopher A. Hunter, Andreas Radbruch, Timothy P. Bushnell, Anna Erdei, Sabine Adam-Klages, Pascale Eede, Van Duc Dang, Rieke Winkelmann, Thomas Korn, Gemma A. Foulds, Dirk Baumjohann, Matthias Schiemann, Manfred Kopf, Jan Kisielow, Lisa Richter, Jochen Huehn, Gloria Martrus, Alexander Scheffold, Jessica G. Borger, Sidonia B G Eckle, John Bellamy Foster, Anna Katharina Simon, Alicia Wong, Mübeccel Akdis, Gisa Tiegs, Toralf Kaiser, James McCluskey, Anna Vittoria Mattioli, Aaron J. Marshall, Hui-Fern Koay, Eva Orlowski-Oliver, Anja E. Hauser, J. Paul Robinson, Jay K. Kolls, Luca Battistini, Mairi McGrath, Jane L. Grogan, Natalio Garbi, Timothy Tree, Kingston H. G. Mills, Stefan H. E. Kaufmann, Wolfgang Schuh, Ryan R. Brinkman, Tim R. Mosmann, Vincenzo Barnaba, Andreas Dolf, Lorenzo Cosmi, Bo Huang, Andreia C. Lino, Baerbel Keller, René A. W. van Lier, Alexandra J. Corbett, Paul S. Frenette, Pleun Hombrink, Helena Radbruch, Sofie Van Gassen, Olivier Lantz, Lorenzo Moretta, Désirée Kunkel, Kirsten A. Ward-Hartstonge, Armin Saalmüller, Leslie Y. T. Leung, Salvador Vento-Asturias, Paola Lanuti, Alicia Martínez-Romero, Sarah Warth, Zhiyong Poon, Diana Dudziak, Andrea Cossarizza, Kovit Pattanapanyasat, Konrad von Volkmann, Jessica P. Houston, Agnès Lehuen, Andrew Filby, Pratip K. Chattopadhyay, Stefano Casola, Annika Wiedemann, Hannes Stockinger, Jürgen Ruland, Arturo Zychlinsky, Claudia Waskow, Katrin Neumann, Ari Waisman, Lucienne Chatenoud, Sudipto Bari, Kamran Ghoreschi, David W. Galbraith, Yvan Saeys, Hamida Hammad, Andrea Gori, Miguel López-Botet, Gabriel Núñez, Sabine Ivison, Michael Hundemer, Dorothea Reimer, Mark C. Dessing, Günter J. Hämmerling, Rudolf A. Manz, Tomas Kalina, Jonas Hahn, Holden T. Maecker, Hendy Kristyanto, Martin S. Davey, Henning Ulrich, Michael L. Dustin, Takashi Saito, Yousuke Takahama, Milena Nasi, Johanna Huber, Jürgen Wienands, Paolo Dellabona, Andreas Schlitzer, Michael D. Leipold, Kerstin H. Mair, Christian Peth, Immo Prinz, Chiara Romagnani, José M. González-Navajas, Josephine Schlosser, Marina Saresella, Matthias Edinger, Dirk Brenner, Nicole Baumgarth, Rikard Holmdahl, Fang-Ping Huang, Guadalupe Herrera, Malte Paulsen, Gergely Toldi, Luka Cicin-Sain, Reiner Schulte, Christina E. Zielinski, Thomas Winkler, Christoph Goettlinger, Philip E. Boulais, Jennie H M Yang, Antonio Celada, Heike Kunze-Schumacher, Julia Tornack, Florian Ingelfinger, Jenny Mjösberg, Andy Riddell, Leonie Wegener, Thomas Höfer, Christoph Hess, James P. Di Santo, Anna E. Oja, J. Kühne, Willem van de Veen, Mary Bebawy, Alberto Mantovani, Bart Everts, Giovanna Lombardi, Laura Maggi, Anouk von Borstel, Pia Kvistborg, Elisabetta Traggiai, A Ochel, Nima Aghaeepour, Charles-Antoine Dutertre, Matthieu Allez, Thomas Höllt, Wenjun Ouyang, Regina Stark, Maries van den Broek, Shimon Sakaguchi, Paul K. Wallace, Silvano Sozzani, Francesca LaRosa, Annette Oxenius, Malgorzata J. Podolska, Ivana Marventano, Wilhelm Gerner, Oliver F. Wirz, Britta Frehse, Gevitha Ravichandran, Martin Herrmann, Carl S. Goodyear, Gary Warnes, Helen Ferry, Stefan Frischbutter, Tim R. Radstake, Salomé LeibundGut-Landmann, Yi Zhao, Axel Schulz, Angela Santoni, Pablo Engel, Daniela C. Hernández, Andreas Acs, Cristiano Scottà, Francesco Annunziato, Thomas Weisenburger, Wolfgang Beisker, Sue Chow, Fritz Melchers, Daniel E. Speiser, Immanuel Kwok, Florent Ginhoux, Dominic A. Boardman, Natalie Stanley, Carsten Watzl, Marie Follo, Erik Lubberts, Andreas Krueger, Susanne Ziegler, Göran K. Hansson, David Voehringer, Antonia Niedobitek, Eleni Christakou, Lai Guan Ng, Sabine Baumgart, Nicholas A Gherardin, Antonio Cosma, Orla Maguire, Jolene Bradford, Daniel Schraivogel, Linda Quatrini, Stephen D. Miller

Publikováno v: European Journal of Immunology, 49(10), 1457-1973. Wiley-VCH
European Journal of Immunology
European Journal of Immunology, Wiley-VCH Verlag, 2019, 49 (10), pp.1457-1973. ⟨10.1002/eji.201970107⟩
European Journal of Immunology, 2019, 49 (10), pp.1457-1973. ⟨10.1002/eji.201970107⟩
Eur J Immunol
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
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European journal of immunology
European journal of immunology, Vol. 49, no.10, p. 1457-1973 (2019)
EUROPEAN JOURNAL OF IMMUNOLOGY
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Digital.CSIC. Repositorio Institucional del CSIC
Volume 49
Issue 10
European journal of immunology, 49(10), 1457-1973. Wiley-VCH Verlag
European Journal of Immunology, 49(10), 1457-1973
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
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r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
Cossarizza, A, Chang, H-D, Radbruch, A, Acs, A, Adam, D, Adam-Klages, S, Agace, W W, Aghaeepour, N, Akdis, M, Allez, M, Almeida, L N, Alvisi, G, Anderson, G, Andrä, I, Annunziato, F, Anselmo, A, Bacher, P, Baldari, C T, Bari, S, Barnaba, V, Barros-Martins, J, Battistini, L, Bauer, W, Baumgart, S, Baumgarth, N, Baumjohann, D, Baying, B, Bebawy, M, Becher, B, Beisker, W, Benes, V, Beyaert, R, Blanco, A, Boardman, D A, Bogdan, C, Borger, J G, Borsellino, G, Boulais, P E, Bradford, J A, Brenner, D, Brinkman, R R, Brooks, A E S, Busch, D H, Büscher, M, Bushnell, T P, Calzetti, F, Cameron, G, Cammarata, I, Cao, X, Cardell, S L, Casola, S, Cassatella, M A, Cavani, A, Celada, A, Chatenoud, L, Chattopadhyay, P K, Chow, S, Christakou, E, Čičin-Šain, L, Clerici, M, Colombo, F S, Cook, L, Cooke, A, Cooper, A M, Corbett, A J, Cosma, A, Cosmi, L, Coulie, P G, Cumano, A, Cvetkovic, L, Dang, V D, Dang-Heine, C, Davey, M S, Davies, D, De Biasi, S, Del Zotto, G, Dela Cruz, G V, Delacher, M, Della Bella, S, Dellabona, P, Deniz, G, Dessing, M, Di Santo, J P, Diefenbach, A, Dieli, F, Dolf, A, Dörner, T, Dress, R J, Dudziak, D, Dustin, M, Dutertre, C-A, Ebner, F, Eckle, S B G, Edinger, M, Eede, P, Ehrhardt, G R A, Eich, M, Engel, P, Engelhardt, B, Erdei, A, Esser, C, Everts, B, Evrard, M, Falk, C S, Fehniger, T A, Felipo-Benavent, M, Ferry, H, Feuerer, M, Filby, A, Filkor, K, Fillatreau, S, Follo, M, Förster, I, Foster, J, Foulds, G A, Frehse, B, Frenette, P S, Frischbutter, S, Fritzsche, W, Galbraith, D W, Gangaev, A, Garbi, N, Gaudilliere, B, Gazzinelli, R T, Geginat, J, Gerner, W, Gherardin, N A, Ghoreschi, K, Gibellini, L, Ginhoux, F, Goda, K, Godfrey, D I, Goettlinger, C, González-Navajas, J M, Goodyear, C S, Gori, A, Grogan, J L, Grummitt, D, Grützkau, A, Haftmann, C, Hahn, J, Hammad, H, Hämmerling, G, Hansmann, L, Hansson, G, Harpur, C M, Hartmann, S, Hauser, A, Hauser, A E, Haviland, D L, Hedley, D, Hernández, D C, Herrera, G, Herrmann, M, Hess, C, Höfer, T, Hoffmann, P, Hogquist, K, Holland, T, Höllt, T, Holmdahl, R, Hombrink, P, Houston, J P, Hoyer, B F, Huang, B, Huang, F-P, Huber, J E, Huehn, J, Hundemer, M, Hunter, C A, Hwang, W Y K, Iannone, A, Ingelfinger, F, Ivison, S M, Jäck, H-M, Jani, P K, Jávega, B, Jonjic, S, Kaiser, T, Kalina, T, Kamradt, T, Kaufmann, S H E, Keller, B, Ketelaars, S L C, Khalilnezhad, A, Khan, S, Kisielow, J, Klenerman, P, Knopf, J, Koay, H-F, Kobow, K, Kolls, J K, Kong, W T, Kopf, M, Korn, T, Kriegsmann, K, Kristyanto, H, Kroneis, T, Krueger, A, Kühne, J, Kukat, C, Kunkel, D, Kunze-Schumacher, H, Kurosaki, T, Kurts, C, Kvistborg, P, Kwok, I, Landry, J, Lantz, O, Lanuti, P, LaRosa, F, Lehuen, A, LeibundGut-Landmann, S, Leipold, M D, Leung, L Y T, Levings, M K, Lino, A C, Liotta, F, Litwin, V, Liu, Y, Ljunggren, H-G, Lohoff, M, Lombardi, G, Lopez, L, López-Botet, M, Lovett-Racke, A E, Lubberts, E, Luche, H, Ludewig, B, Lugli, E, Lunemann, S, Maecker, H T, Maggi, L, Maguire, O, Mair, F, Mair, K H, Mantovani, A, Manz, R A, Marshall, A J, Martínez-Romero, A, Martrus, G, Marventano, I, Maslinski, W, Matarese, G, Mattioli, A V, Maueröder, C, Mazzoni, A, McCluskey, J, McGrath, M, McGuire, H M, McInnes, I B, Mei, H E, Melchers, F, Melzer, S, Mielenz, D, Miller, S D, Mills, K H G, Minderman, H, Mjösberg, J, Moore, J, Moran, B, Moretta, L, Mosmann, T R, Müller, S, Multhoff, G, Muñoz, L E, Münz, C, Nakayama, T, Nasi, M, Neumann, K, Ng, L G, Niedobitek, A, Nourshargh, S, Núñez, G, O'Connor, J-E, Ochel, A, Oja, A, Ordonez, D, Orfao, A, Orlowski-Oliver, E, Ouyang, W, Oxenius, A, Palankar, R, Panse, I, Pattanapanyasat, K, Paulsen, M, Pavlinic, D, Penter, L, Peterson, P, Peth, C, Petriz, J, Piancone, F, Pickl, W F, Piconese, S, Pinti, M, Pockley, A G, Podolska, M J, Poon, Z, Pracht, K, Prinz, I, Pucillo, C E M, Quataert, S A, Quatrini, L, Quinn, K M, Radbruch, H, Radstake, T R D J, Rahmig, S, Rahn, H-P, Rajwa, B, Ravichandran, G, Raz, Y, Rebhahn, J A, Recktenwald, D, Reimer, D, Reis E Sousa, C, Remmerswaal, E B M, Richter, L, Rico, L G, Riddell, A, Rieger, A M, Robinson, J P, Romagnani, C, Rubartelli, A, Ruland, J, Saalmüller, A, Saeys, Y, Saito, T, Sakaguchi, S, Sala-de-Oyanguren, F, Samstag, Y, Sanderson, S, Sandrock, I, Santoni, A, Sanz, R B, Saresella, M, Sautes-Fridman, C, Sawitzki, B, Schadt, L, Scheffold, A, Scherer, H U, Schiemann, M, Schildberg, F A, Schimisky, E, Schlitzer, A, Schlosser, J, Schmid, S, Schmitt, S, Schober, K, Schraivogel, D, Schuh, W, Schüler, T, Schulte, R, Schulz, A R, Schulz, S R, Scottá, C, Scott-Algara, D, Sester, D P, Shankey, T V, Silva-Santos, B, Simon, A K, Sitnik, K M, Sozzani, S, Speiser, D E, Spidlen, J, Stahlberg, A, Stall, A M, Stanley, N, Stark, R, Stehle, C, Steinmetz, T, Stockinger, H, Takahama, Y, Takeda, K, Tan, L, Tárnok, A, Tiegs, G, Toldi, G, Tornack, J, Traggiai, E, Trebak, M, Tree, T I M, Trotter, J, Trowsdale, J, Tsoumakidou, M, Ulrich, H, Urbanczyk, S, van de Veen, W, van den Broek, M, van der Pol, E, Van Gassen, S, Van Isterdael, G, van Lier, R A W, Veldhoen, M, Vento-Asturias, S, Vieira, P, Voehringer, D, Volk, H-D, von Borstel, A, von Volkmann, K, Waisman, A, Walker, R V, Wallace, P K, Wang, S A, Wang, X M, Ward, M D, Ward-Hartstonge, K A, Warnatz, K, Warnes, G, Warth, S, Waskow, C, Watson, J V, Watzl, C, Wegener, L, Weisenburger, T, Wiedemann, A, Wienands, J, Wilharm, A, Wilkinson, R J, Willimsky, G, Wing, J B, Winkelmann, R, Winkler, T H, Wirz, O F, Wong, A, Wurst, P, Yang, J H M, Yang, J, Yazdanbakhsh, M, Yu, L, Yue, A, Zhang, H, Zhao, Y, Ziegler, S M, Zielinski, C, Zimmermann, J & Zychlinsky, A 2019, ' Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) ', European Journal of Immunology, vol. 49, no. 10, pp. 1457-1973 . https://doi.org/10.1002/eji.201970107

All authors: Andrea Cossarizza Hyun‐Dong Chang Andreas Radbruch Andreas Acs Dieter Adam Sabine Adam‐Klages William W. Agace Nima Aghaeepour Mübeccel Akdis Matthieu Allez Larissa Nogueira Almeida Giorgia Alvisi Graham Anderson Immanuel Andrä Fra

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