Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Thomas, Kolben"'
Autor:
Mareike Mannewitz, Thomas Kolben, Carolin Perleberg, Sarah Meister, Laura Hahn, Sophie Mitter, Elisa Schmoeckel, Sven Mahner, Stefanie Corradini, Fabian Trillsch, Mirjana Kessler, Udo Jeschke, Susanne Beyer
Publikováno v:
Translational Oncology, Vol 50, Iss , Pp 102116- (2024)
Objectives: The chemokine CCL22 is recognized for recruiting immunosuppressive regulatory T-cells (Treg) that contribute to disease progression in various tumor entities helping them to evade the host immune response. Our study aims to identify the e
Externí odkaz:
https://doaj.org/article/a1d7f82746124e98acf4d69eadacae70
Autor:
Christina Buschmann, Laura Unverdorben, Julia Knabl, Stefan Hutter, Sarah Meister, Susanne Beyer, Maximiliane Burgmann, Lucia Keilmann, Alaleh Zati zehni, Elisa Schmoeckel, Mirjana Kessler, Udo Jeschke, Sven Mahner, Thomas Kolben, Franziska Ganster, Alexander Burges
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 11, Pp 8840-8851 (2023)
Galectins are known to play an important role in immunoregulatory processes and autoimmune diseases. Galectin-10 is a cytoplasmic protein of human eosinophils and is involved in various eosinophilic diseases. Since increased galectin expression is al
Externí odkaz:
https://doaj.org/article/f3b37256f3df4904be4d65b037dceb5c
Autor:
Florian Schindler, Timo Schinkoethe, Sven Mahner, Thomas Kolben, Rachel Wuerstlein, Carsten Culmsee, Nadia Harbeck, Tanja K. Eggersmann
Publikováno v:
Therapeutic Advances in Drug Safety, Vol 14 (2023)
Background: Modern oral antineoplastic and immune-modulating drugs offer an array of therapeutic advantages, and yet pose challenges in daily use for patients, physicians and pharmacists. In contrast to intravenous administration, these drugs are not
Externí odkaz:
https://doaj.org/article/5cc9960574534755b9dd798a7f3e2185
Autor:
Susann Badmann, Doris Mayr, Elisa Schmoeckel, Anna Hester, Christina Buschmann, Susanne Beyer, Thomas Kolben, Fabian Kraus, Anca Chelariu-Raicu, Alexander Burges, Sven Mahner, Udo Jeschke, Fabian Trillsch, Bastian Czogalla
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract In recurrent epithelial ovarian cancer (EOC) most patients develop platinum-resistance. On molecular level the NRF2 pathway, a cellular defense mechanism against reactive oxygen species, is induced. In this study, we investigate AKR1C1/2, ta
Externí odkaz:
https://doaj.org/article/51dfe0d42da94dd1b154d81478a61c37
Autor:
Ina Rohwedder, Lou Martha Wackerbarth, Kristina Heinig, Annamaria Ballweg, Johannes Altstätter, Myriam Ripphahn, Claudia Nussbaum, Melanie Salvermoser, Susanne Bierschenk, Tobias Straub, Matthias Gunzer, Marc Schmidt-Supprian, Thomas Kolben, Christian Schulz, Averil Ma, Barbara Walzog, Matthias Heinig, Markus Sperandio
Publikováno v:
JCI Insight, Vol 8, Iss 4 (2023)
Newborns are at high risk of developing neonatal sepsis, particularly if born prematurely. This has been linked to divergent requirements the immune system has to fulfill during intrauterine compared with extrauterine life. By transcriptomic analysis
Externí odkaz:
https://doaj.org/article/e87a9995376c4685aecbb7a8084026ca
Autor:
Lili Lin, Christina Kuhn, Nina Ditsch, Thomas Kolben, Bastian Czogalla, Susanne Beyer, Fabian Trillsch, Elisa Schmoeckel, Doris Mayr, Sven Mahner, Udo Jeschke, Anna Hester
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-16 (2021)
Abstract Background An abundance of tumor-associated macrophages has been shown to be an independent prognostic factor for a poor prognosis of human breast cancer (BC). Adipose tissue accounts for the largest proportion of the breast and has also bee
Externí odkaz:
https://doaj.org/article/b079fccf2b264727a13d7de0710e4203
Autor:
Marinus Huber, Kosmas V Kepesidis, Liudmila Voronina, Frank Fleischmann, Ernst Fill, Jacqueline Hermann, Ina Koch, Katrin Milger-Kneidinger, Thomas Kolben, Gerald B Schulz, Friedrich Jokisch, Jürgen Behr, Nadia Harbeck, Maximilian Reiser, Christian Stief, Ferenc Krausz, Mihaela Zigman
Publikováno v:
eLife, Vol 10 (2021)
Recent omics analyses of human biofluids provide opportunities to probe selected species of biomolecules for disease diagnostics. Fourier-transform infrared (FTIR) spectroscopy investigates the full repertoire of molecular species within a sample at
Externí odkaz:
https://doaj.org/article/eaad08e071b84de89e14ee30b1aa50b7
Autor:
Nicole Elisabeth Topalov, Doris Mayr, Clemens Scherer, Anca Chelariu-Raicu, Susanne Beyer, Anna Hester, Fabian Kraus, Mingjun Zheng, Till Kaltofen, Thomas Kolben, Alexander Burges, Sven Mahner, Fabian Trillsch, Udo Jeschke, Bastian Czogalla
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The impact of Actin beta-like 2 (ACTBL2), a novel described actin isoform, on epithelial ovarian cancer (EOC) biology has not been investigated so far. In this study, we analyzed the prognostic and functional significance of ACTBL2 and its regulatory
Externí odkaz:
https://doaj.org/article/a8ab4bea62a044918dd18ca46829d427
Autor:
Bastian Czogalla, Alexandra Partenheimer, Susann Badmann, Elisa Schmoeckel, Doris Mayr, Thomas Kolben, Susanne Beyer, Anna Hester, Alexander Burges, Sven Mahner, Udo Jeschke, Fabian Trillsch
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100910- (2021)
Background:: Enolase-1, primarily known for its role in glucose metabolism, is overexpressed in various cancer entities. In contrast its alternative spliced nuclear isoform MBP-1 acts as a tumor suppressor. The aim of this study is to analyze the pro
Externí odkaz:
https://doaj.org/article/10b346fbbd114b0487ee2ccde22428e1
Autor:
Laura Hahn, Sarah Meister, Mareike Mannewitz, Susanne Beyer, Stefanie Corradini, Uwe Hasbargen, Sven Mahner, Udo Jeschke, Thomas Kolben, Alexander Burges
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 707 (2022)
Preeclampsia (PE) is a severe pregnancy disorder with a pathophysiology not yet completely understood and without curative therapy. The histone modifications H3K4me3 and H3K9ac, as well as galectin-2 (Gal-2), are known to be decreased in PE. To gain
Externí odkaz:
https://doaj.org/article/0835b14cf78240cd8d43b8b82f70132f