Zobrazeno 1 - 10
of 288
pro vyhledávání: '"Thomas, Knöpfel"'
Autor:
Yuqi Liang, Junhao Liang, Chenchen Song, Mianxin Liu, Thomas Knöpfel, Pulin Gong, Changsong Zhou
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
The cerebral cortex has ongoing electrical activities with rich and complex patterns in space and time. Here, the authors use optical voltage imaging in mice and computational methods, relating these complexities to different levels of wakefulness.
Externí odkaz:
https://doaj.org/article/ec474d9973c14a91ae5133fe1faaf1c0
Autor:
Åsa Lina M. Jönsson, Nati Hernando, Thomas Knöpfel, Susie Mogensen, Elisabeth Bendstrup, Ole Hilberg, Jane Hvarregaard Christensen, Ulf Simonsen, Carsten A. Wagner
Publikováno v:
Human Genomics, Vol 16, Iss 1, Pp 1-11 (2022)
Abstract Background Variants in SLC34A2 encoding the sodium-dependent phosphate transport protein 2b (NaPi-IIb) cause the rare lung disease pulmonary alveolar microlithiasis (PAM). PAM is characterised by the deposition of calcium-phosphate concretio
Externí odkaz:
https://doaj.org/article/b26c4688d07040dca763b1684c455225
Inhibition is a prevalent mode of activity in the neocortex around awake hippocampal ripples in mice
Publikováno v:
eLife, Vol 12 (2023)
Coordinated peri-ripple activity in the hippocampal-neocortical network is essential for mnemonic information processing in the brain. Hippocampal ripples likely serve different functions in sleep and awake states. Thus, the corresponding neocortical
Externí odkaz:
https://doaj.org/article/924fdffa35ba468786103704aebc9906
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-20 (2021)
Abstract Cholinergic modulation of brain activity is fundamental for awareness and conscious sensorimotor behaviours, but deciphering the timing and significance of acetylcholine actions for these behaviours is challenging. The widespread nature of c
Externí odkaz:
https://doaj.org/article/73730454205d4df7a402ff43b1062d0f
Autor:
Raziye Karapinar, Jan Claudius Schwitalla, Dennis Eickelbeck, Johanna Pakusch, Brix Mücher, Michelle Grömmke, Tatjana Surdin, Thomas Knöpfel, Melanie D. Mark, Ida Siveke, Stefan Herlitze
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Microbial rhodopsins can be used to control action potentials, while animal opsins can be used to control intracellular signaling pathways. The authors identify Opn7b as constitutively active Gi/o coupled receptor that can be deactivated by light and
Externí odkaz:
https://doaj.org/article/cd6b728c8c2a41f6902c7cf1ab408a53
Autor:
Bogachan Tahirbegi, Alastair J. Magness, Maria Elena Piersimoni, Xiangyu Teng, James Hooper, Yuan Guo, Thomas Knöpfel, Keith R. Willison, David R. Klug, Liming Ying
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Aggregation kinetics of proteins and peptides have been studied extensively due to their significance in many human diseases, including neurodegenerative disorders, and the roles they play in some key physiological processes. However, most of these s
Externí odkaz:
https://doaj.org/article/75ea4c38a6e541a4b5653121b314c1b0
Autor:
Thomas Knöpfel, Yann Sweeney, Carola I. Radulescu, Nawal Zabouri, Nazanin Doostdar, Claudia Clopath, Samuel J. Barnes
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Sensory stimuli usually arrive simultaneously but the neural-circuit mechanisms that combine multiple streams of sensory information are incompletely understood. The authors here show that visual-auditory pairing drives plasticity in multi-modal neur
Externí odkaz:
https://doaj.org/article/b59fcdd02a4047f1b6117f7a8958b6d5
Publikováno v:
iScience, Vol 12, Iss , Pp 121-131 (2019)
Summary: Similar universal phenomena can emerge in different complex systems when those systems share a common symmetry in their governing laws. In physical systems operating near a critical phase transition, the governing physical laws obey a fracta
Externí odkaz:
https://doaj.org/article/f1f4a7c056a74b9abb1027cdb5ae0e20
Autor:
Peter Quicke, Chenchen Song, Eric J. McKimm, Milena M. Milosevic, Carmel L. Howe, Mark Neil, Simon R. Schultz, Srdjan D. Antic, Amanda J. Foust, Thomas Knöpfel
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Externí odkaz:
https://doaj.org/article/99c5d38c192b4eb59f17d2ce03014c15
Autor:
Peter Quicke, Chenchen Song, Eric J. McKimm, Milena M. Milosevic, Carmel L. Howe, Mark Neil, Simon R. Schultz, Srdjan D. Antic, Amanda J. Foust, Thomas Knöpfel
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Voltage imaging of many neurons simultaneously at single-cell resolution is hampered by the difficulty of detecting small voltage signals from overlapping neuronal processes in neural tissue. Recent advances in genetically encoded voltage indicator (
Externí odkaz:
https://doaj.org/article/6a0044e1d29140aab159ccbfbb0217e9