Zobrazeno 1 - 10
of 267
pro vyhledávání: '"Thomas, Karn"'
Autor:
Bruno Valentin Sinn, Katharina Sychra, Michael Untch, Thomas Karn, Marion van Mackelenbergh, Jens Huober, Wolfgang Schmitt, Frederik Marmé, Christian Schem, Christine Solbach, Elmar Stickeler, Hans Tesch, Peter A. Fasching, Andreas Schneeweiss, Volkmar Müller, Johannes Holtschmidt, Valentina Nekljudova, Sibylle Loibl, Carsten Denkert
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Background Patients with pathologic complete response (pCR) to neoadjuvant chemotherapy for invasive breast cancer (BC) have better outcomes, potentially warranting less extensive surgical and systemic treatments. Early prediction of treatme
Externí odkaz:
https://doaj.org/article/7254adee1eef456f91cca8c6f84490e2
Autor:
Chiara Massa, Thomas Karn, Karsten Weber, Andreas Schneeweiss, Claus Hanusch, Jens Uwe Blohmer, Dirk‐Michael Zahm, Christian Jackisch, Marion van Mackelenbergh, Jörg Thomalla, Frederik Marmé, Jens Huober, Volkmar Müller, Christian Schem, Anja Müller, Elmar Stickeler, Katharina Biehl, Peter A. Fasching, Michael Untch, Sibylle Loibl, Carsten Denkert, Barbara Seliger
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 4, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/f921f7466a0a4b568dfafa8ea0d35cf6
Autor:
Francesca Reimer, Sarah Bryan, Karen Legler, Thomas Karn, Serenella Eppenberger-Castori, Jakob Matschke, Thais Pereira-Veiga, Harriet Wikman, Isabell Witzel, Volkmar Müller, Barbara Schmalfeldt, Karin Milde-Langosch, Udo Schumacher, Christine Stürken, Leticia Oliveira-Ferrer
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background The disruption of epithelial features represents a critical step during breast cancer spread. In this context, the dysregulation of desmosomal proteins has been associated with malignant progression and metastasis formation. Curio
Externí odkaz:
https://doaj.org/article/7dd783cb52b64e1398cec4d6e4826b38
Autor:
Tao Qing, Thomas Karn, Mariya Rozenblit, Julia Foldi, Michal Marczyk, Naing Lin Shan, Kim Blenman, Uwe Holtrich, Kevin Kalinsky, Funda Meric-Bernstam, Lajos Pusztai
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract The RxPONDER and TAILORx trials demonstrated benefit from adjuvant chemotherapy in patients age ≤ 50 with node-positive breast cancer and Recurrence Score (RS) 0–26, and in node-negative disease with RS 16–25, respectively, but no bene
Externí odkaz:
https://doaj.org/article/7ff2397038c543cb90f08b59011921fa
Autor:
Jonas Leichsenring, Valentina Vladimirova, Christine Solbach, Thomas Karn, Beyhan Ataseven, Bruno Valentin Sinn, Jana Barinoff, Volkmar Müller, Jens-Uwe Blohmer, Christian Schem, Knut Engels, Frederik Marmé, Annette Fisseler-Eckhoff, Peter A. Fasching, Elmar Stickeler, Marion van Mackelenbergh, Carsten Denkert, Albrecht Stenzinger, Sibylle Loibl, Stefan Gröschel
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Overexpression of the EVI1 (ecotropic viral integration site 1) oncogene has recently been implicated as a prognostic factor in breast cancer (BC), particularly in triple-negative BC (TNBC). In this study we aimed to investigate f
Externí odkaz:
https://doaj.org/article/c3d9b3683e1d4e1b93d349f80d056d05
Autor:
Christine Stürken, Volker Möbus, Karin Milde-Langosch, Sabine Schmatloch, Peter A. Fasching, Josef Rüschoff, Elmar Stickeler, Rolf-Peter Henke, Carsten Denkert, Lars Hanker, Christian Schem, Valentina Vladimirova, Thomas Karn, Valentina Nekljudova, Claus-Henning Köhne, Frederik Marmé, Udo Schumacher, Sibylle Loibl, Volkmar Müller
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Breast cancer (BC) is the most frequent female cancer and preferentially metastasizes to bone. The transcription factor TGFB-induced factor homeobox 1 (TGIF) is involved in bone metabolism. However, it is not yet known whether TGI
Externí odkaz:
https://doaj.org/article/c69ff00bda2f4529a85614e57c4f1988
Autor:
Juliana Pereira Lopes Gonçalves, Christine Bollwein, Aurelia Noske, Anne Jacob, Paul Jank, Sibylle Loibl, Valentina Nekljudova, Peter A. Fasching, Thomas Karn, Frederik Marmé, Volkmar Müller, Christian Schem, Bruno Valentin Sinn, Elmar Stickeler, Marion van Mackelenbergh, Wolfgang D. Schmitt, Carsten Denkert, Wilko Weichert, Kristina Schwamborn
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2860 (2023)
Immunohistochemical evaluation of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor-2 status stratify the different subtypes of breast cancer and define the treatment course. Triple-negative breast cancer (TNBC), wh
Externí odkaz:
https://doaj.org/article/2d79136acc944af3a4ff3abea8722fd2
Autor:
Bruno Valentin Sinn, Karsten E. Weber, Wolfgang Daniel Schmitt, Peter A. Fasching, William Fraser Symmans, Jens-Uwe Blohmer, Thomas Karn, Eliane Tabea Taube, Frederick Klauschen, Frederik Marmé, Christian Schem, Elmar Stickeler, Beyhan Ataseven, Jens Huober, Gunter von Minckwitz, Barbara Seliger, Carsten Denkert, Sibylle Loibl
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-9 (2019)
Abstract Background Clinical application of cancer immunotherapy requires a better understanding of tumor immunogenicity and the tumor microenvironment. HLA class I molecules present antigens to CD8+ cytotoxic cells. Their loss or downregulation is f
Externí odkaz:
https://doaj.org/article/fe25c57ca712482c9d848c7a1e558deb
Autor:
Peter A. Fasching, Christopher Szeto, Carsten Denkert, Stephen Benz, Karsten Weber, Patricia Spilman, Jan Budczies, Andreas Schneeweiss, Elmar Stickeler, Sabine Schmatloch, Christian Jackisch, Thomas Karn, Hans Peter Sinn, Mathias Warm, Marion van Mackelenbergh, Shahrooz Rabizadeh, Christian Schem, Ernst Heinmöller, Volkmar Mueller, Frederik Marmé, Patrick Soon-Shiong, Valentina Nekljudova, Michael Untch, Sibylle Loibl
Publikováno v:
Clinical Cancer Research. :OF1-OF10
Purpose: Tumor microenvironment (TME) immune markers have been correlated with both response to neoadjuvant therapy and prognosis in patients with breast cancer. Here, immune-cell activity of breast cancer tumors was inferred by expression-based anal
Autor:
Paul Jank, Claire Gehlhaar, Bianca Lederer, Caterina Fontanella, Andreas Schneeweiss, Thomas Karn, Frederik Marmé, Hans-Peter Sinn, Marion van Mackelenbergh, Bruno Sinn, Dirk-Michael Zahm, Barbara Ingold-Heppner, Christian Schem, Elmar Stickeler, Peter A Fasching, Valentina Nekljudova, Eliane Tabea Taube, Frank Heppner, Volkmar Müller, Carsten Denkert, Sibylle Loibl
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257142 (2021)
[This corrects the article DOI: 10.1371/journal.pone.0238021.].
Externí odkaz:
https://doaj.org/article/8aca656624204da98cdb0cb958334577