Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Thomas, Hellmark"'
Autor:
Sofia Smargianaki, Evelina Elmér, Sandra Lilliebladh, Sophie Ohlsson, Åsa Pettersson, Thomas Hellmark, Åsa CM Johansson
Publikováno v:
Journal of Immunology Research, Vol 2024 (2024)
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a group of autoimmune diseases with inflammation affecting small blood vessels and includes granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). In this s
Externí odkaz:
https://doaj.org/article/bbee54f7bf7f4c97bfc82bfb37c0c826
Publikováno v:
Frontiers in Nephrology, Vol 3 (2023)
BackgroundMany pathological processes can disrupt the integrity of the glomerular capillary wall and cause a massive leakage of protein, resulting in nephrotic syndrome (NS). Clinical parameters such as age, sex, renal function, presence of diabetes,
Externí odkaz:
https://doaj.org/article/8635f8e32a154803a949ca9d04e83486
Autor:
Wael Bahnan, Lotta Happonen, Hamed Khakzad, Vibha Kumra Ahnlide, Therese deNeergaard, Sebastian Wrighton, Oscar André, Eleni Bratanis, Di Tang, Thomas Hellmark, Lars Björck, Oonagh Shannon, Lars Malmström, Johan Malmström, Pontus Nordenfelt
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 2, Pp n/a-n/a (2023)
Abstract Group A streptococci have evolved multiple strategies to evade human antibodies, making it challenging to create effective vaccines or antibody treatments. Here, we have generated antibodies derived from the memory B cells of an individual w
Externí odkaz:
https://doaj.org/article/2bcb7da2abe14c5fb5c5a0341f1349d2
Autor:
Julia Westerlund, Sandra Askman, Åsa Pettersson, Thomas Hellmark, Åsa C. M. Johansson, Markus Hansson
Publikováno v:
Journal of Immunology Research, Vol 2022 (2022)
Normal density granulocytes (NDGs) can suppress T-cell responses in a similar way as myeloid-derived suppressor cells (MDSCs). In this study, we tested the hypothesis that NDGs from healthy donors preferentially inhibit T helper 1 (Th1) cells and inv
Externí odkaz:
https://doaj.org/article/134d1ba88be64c9f856e34e50b522533
Autor:
Evelina Elmér, Per Nived, Åsa Pettersson, Lillemor Skattum, Thomas Hellmark, Meliha C. Kapetanovic, Åsa C. M. Johansson
Publikováno v:
Journal of Immunology Research, Vol 2022 (2022)
Patients with rheumatoid arthritis (RA) have an increased risk of infections; therefore, immunization against vaccine-preventable diseases is important. Methotrexate (MTX) impairs the antibody response to pneumococcal conjugate vaccine (PCV) in patie
Externí odkaz:
https://doaj.org/article/230ffa5994244a0f87aab85fc8e68d7b
Autor:
Wael Bahnan, Sebastian Wrighton, Martin Sundwall, Anna Bläckberg, Olivia Larsson, Urban Höglund, Hamed Khakzad, Magdalena Godzwon, Maria Walle, Elisabeth Elder, Anna Söderlund Strand, Lotta Happonen, Oscar André, Johannes Kumra Ahnlide, Thomas Hellmark, Vidar Wendel-Hansen, Robert PA. Wallin, Johan Malmstöm, Lars Malmström, Mats Ohlin, Magnus Rasmussen, Pontus Nordenfelt
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Spike-specific antibodies are central to effective COVID19 immunity. Research efforts have focused on antibodies that neutralize the ACE2-Spike interaction but not on non-neutralizing antibodies. Antibody-dependent phagocytosis is an immune mechanism
Externí odkaz:
https://doaj.org/article/f92905abfadc4d269db7f2ae1d052963
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background Arteriosclerosis is prevalent in patients with chronic kidney disease (CKD). Our aims were to investigate (1) the effects of 12 months of either balance- or strength- both in combination with endurance training on abdominal aortic
Externí odkaz:
https://doaj.org/article/b2f3493eea94449d82cbea0744104b92
Publikováno v:
BMC Rheumatology, Vol 3, Iss 1, Pp 1-12 (2019)
Abstract Background Anti-neutrophil cytoplasmic antibodies associated vasculitides (AAV) are characterized by autoimmune small vessel inflammation. Eosinophils are multifunctional cells with both pro-inflammatory and immunoregulatory properties. Tiss
Externí odkaz:
https://doaj.org/article/8a895880e7aa4619891e23dd3aa225a1
Autor:
Julia Petersson, Sandra Askman, Åsa Pettersson, Stina Wichert, Thomas Hellmark, Åsa C. M. Johansson, Markus Hansson
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Activated normal density granulocytes (NDGs) can suppress T-cell responses in a similar way as myeloid-derived suppressor cells (MDSCs). In this study, we tested the hypothesis that NDGs from blood and bone marrow of multiple myeloma (MM) patients ha
Externí odkaz:
https://doaj.org/article/eaf08f03da904bdd832aa4ad62b746ab
Autor:
Evelina Elmér, Sofia Smargianaki, Åsa Pettersson, Lillemor Skattum, Sophie Ohlsson, Thomas Hellmark, Åsa C. M. Johansson
Publikováno v:
Journal of Immunology Research, Vol 2020 (2020)
B cells are thought to play a central role in the pathogenesis of antineutrophil cytoplasmic antibody- (ANCA-) associated vasculitis (AAV). ANCAs have been proposed to cause vasculitis by activating primed neutrophils to damage small blood vessels. W
Externí odkaz:
https://doaj.org/article/dbab7619cb3949da94d64ae32baa1600