Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Thomas, Heimerl"'
Autor:
Franziska L. Sendker, Tabea Schlotthauer, Christopher-Nils Mais, Yat Kei Lo, Mathias Girbig, Stefan Bohn, Thomas Heimerl, Daniel Schindler, Arielle Weinstein, Brian P. H. Metzger, Joseph W. Thornton, Arvind Pillai, Gert Bange, Jan M. Schuller, Georg K. A. Hochberg
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Many enzymes assemble into homomeric protein complexes comprising multiple copies of one protein. Because structural form is usually assumed to follow function in biochemistry, these assemblies are thought to evolve because they provide some
Externí odkaz:
https://doaj.org/article/a2763d86061445bab29bce650bb2b0cc
Autor:
François-Xavier Lehr, Bruno Pavletić, Timo Glatter, Thomas Heimerl, Ralf Moeller, Henrike Niederholtmeyer
Publikováno v:
npj Microgravity, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract On-demand biomanufacturing has the potential to improve healthcare and self-sufficiency during space missions. Cell-free transcription and translation reactions combined with DNA blueprints can produce promising therapeutics like bacteriopha
Externí odkaz:
https://doaj.org/article/64805d34b68d426e8885228ad70afaf5
Autor:
Marie Burt, Georgia Angelidou, Christopher Nils Mais, Christian Preußer, Timo Glatter, Thomas Heimerl, Rüdiger Groß, Javier Serrania, Gowtham Boosarpu, Elke Pogge von Strandmann, Janis A. Müller, Gert Bange, Anke Becker, Mareike Lehmann, Danny Jonigk, Lavinia Neubert, Hinrich Freitag, Nicole Paczia, Bernd Schmeck, Anna Lena Jung
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 5, Pp n/a-n/a (2024)
Abstract The continuous emergence of multidrug‐resistant bacterial pathogens poses a major global healthcare challenge, with Klebsiella pneumoniae being a prominent threat. We conducted a comprehensive study on K. pneumoniae’s antibiotic resistan
Externí odkaz:
https://doaj.org/article/d578823b51904a85bb20616a75988ddc
Autor:
Elena Bittner, Thorsten Stehlik, Jason Lam, Lazar Dimitrov, Thomas Heimerl, Isabelle Schöck, Jannik Harberding, Anita Dornes, Nikola Heymons, Gert Bange, Maya Schuldiner, Einat Zalckvar, Michael Bölker, Randy Schekman, Johannes Freitag
Publikováno v:
PLoS Biology, Vol 22, Iss 2, p e3002508 (2024)
Peroxisomes are organelles with crucial functions in oxidative metabolism. To correctly target to peroxisomes, proteins require specialized targeting signals. A mystery in the field is the sorting of proteins that carry a targeting signal for peroxis
Externí odkaz:
https://doaj.org/article/a57ddc3ae94048c88ef32add6919bf2a
Autor:
Katrin Laakmann, Jorina Mona Eckersberg, Moritz Hapke, Marie Wiegand, Jeff Bierwagen, Isabell Beinborn, Christian Preußer, Elke Pogge von Strandmann, Thomas Heimerl, Bernd Schmeck, Anna Lena Jung
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Sepsis is one of the leading causes of death worldwide and characterized by blood stream infections associated with a dysregulated host response and endothelial cell (EC) dysfunction. Ribonuclease 1 (RNase1) acts as a protective f
Externí odkaz:
https://doaj.org/article/7c0269688b8b458fb4d7267fe2e39b81
Autor:
Jeff Bierwagen, Marie Wiegand, Katrin Laakmann, Olga Danov, Hannah Limburg, Stefanie Muriel Herbel, Thomas Heimerl, Jens Dorna, Danny Jonigk, Christian Preußer, Wilhelm Bertrams, Armin Braun, Katherina Sewald, Leon N. Schulte, Stefan Bauer, Elke Pogge von Strandmann, Eva Böttcher-Friebertshäuser, Bernd Schmeck, Anna Lena Jung
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Gram-negative bacteria naturally secrete nano-sized outer membrane vesicles (OMVs), which are important mediators of communication and pathogenesis. OMV uptake by host cells activates TLR signalling via transported PAMPs. As important reside
Externí odkaz:
https://doaj.org/article/5ab97f46113346758e29ef1c0e67adfd
Autor:
Rogelio Hernández-Tamayo, Niklas Steube, Thomas Heimerl, Georg K. A. Hochberg, Peter L. Graumann
Publikováno v:
mSphere, Vol 7, Iss 6 (2022)
ABSTRACT RecA plays a central role in DNA repair and is a main actor involved in homologous recombination (HR). In vivo, RecA forms filamentous structures termed “threads,” which are essential for HR, but whose nature is still ill defined. We sho
Externí odkaz:
https://doaj.org/article/946770b493494bbbb282a2a1360da27f
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Peroxisomes participate in several important metabolic processes in eukaryotic cells, such as the detoxification of reactive oxygen species (ROS) or the degradation of fatty acids by β-oxidation. Recently, the presence of peroxisomes in the cryptoph
Externí odkaz:
https://doaj.org/article/dea964976ce9438b97220d68d8689769
Autor:
Daniel Andreas Orlando Rotter, Christoph Heger, Christian Kühm, Nina Schmidt, Antje Schäfer, Thomas Heimerl, Matthias Mack, Peter L. Graumann
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Flavins are ubiquitous molecules in life as they serve as important enzyme cofactors. In the Gram-positive, soil-dwelling bacterium Bacillus subtilis, four well-characterized gene products (the enzymes RibDG, RibE, RibAB, and RibH) catalyze the biosy
Externí odkaz:
https://doaj.org/article/7c617dd5d6d0420fa7d8deb3abe24cec
Autor:
Simon Dersch, Christian Reimold, Joshua Stoll, Hannes Breddermann, Thomas Heimerl, Hervé Joel Defeu Soufo, Peter L. Graumann
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-17 (2020)
Abstract Background MreB is a bacterial ortholog of actin and forms mobile filaments underneath the cell membrane, perpendicular to the long axis of the cell, which play a crucial role for cell shape maintenance. We wished to visualize Bacillus subti
Externí odkaz:
https://doaj.org/article/bc1346d4733f4054a1c6b7fce0ab0037