Zobrazeno 1 - 10
of 651
pro vyhledávání: '"Thomas, Hartung"'
Autor:
Dowlette-Mary Alam El Din, Jeongwon Shin, Alexandra Lysinger, Matthew J. Roos, Erik C. Johnson, Timothy J. Shafer, Thomas Hartung, Lena Smirnova
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
The increasing prevalence of neurodevelopmental disorders has highlighted the need for improved testing methods to determine developmental neurotoxicity (DNT) hazard for thousands of chemicals. This paper proposes the integration of organoid intellig
Externí odkaz:
https://doaj.org/article/486db674dadc4af5b5bb5bf31a061d27
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/734c1384af364a6f8560797c69c41b29
Autor:
Brett J. Kagan, Michael Mahlis, Anjali Bhat, Josh Bongard, Victor M. Cole, Phillip Corlett, Christopher Gyngell, Thomas Hartung, Bianca Jupp, Michael Levin, Tamra Lysaght, Nicholas Opie, Adeel Razi, Lena Smirnova, Ian Tennant, Peter Thestrup Wade, Ge Wang
Publikováno v:
The Innovation, Vol 5, Iss 5, Pp 100658- (2024)
Summary: Disagreements about language use are common both between and within fields. Where interests require multidisciplinary collaboration or the field of research has the potential to impact society at large, it becomes critical to minimize these
Externí odkaz:
https://doaj.org/article/2c33612d627242ab9945fafc6f861c74
Autor:
Simon Cauchemez, Giulio Cossu, Nathalie Delzenne, Eran Elinav, Didier Fassin, Alain Fischer, Thomas Hartung, Dipak Kalra, Mihai Netea, Johan Neyts, Rino Rappuoli, Mariagrazia Pizza, Melanie Saville, Pamela Tenaerts, Gerry Wright, Philippe Sansonetti, Michel Goldman
Publikováno v:
Frontiers in Science, Vol 2 (2024)
The COVID-19 pandemic accelerated research and innovation across numerous fields of medicine. It emphasized how disease concepts must reflect dynamic and heterogeneous interrelationships between physical characteristics, genetics, co-morbidities, env
Externí odkaz:
https://doaj.org/article/da0e62dbfbd7426c89e6529b3f274d4f
Autor:
Thomas Hartung
Publikováno v:
Frontiers in Drug Discovery, Vol 4 (2024)
Animals like mice and rats have long been used in medical research to help understand disease and test potential new treatments before human trials. However, while animal studies have contributed to important advances, too much reliance on animal mod
Externí odkaz:
https://doaj.org/article/d6c68c28933a414db9c90ffa3f8e778d
Autor:
Alessio Butera, Lena Smirnova, Elisa Ferrando‐May, Thomas Hartung, Thomas Brunner, Marcel Leist, Ivano Amelio
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 9, Pp 1-6 (2023)
Abstract Human health is determined both by genetics (G) and environment (E). This is clearly illustrated in groups of individuals who are exposed to the same environmental factor showing differential responses. A quantitative measure of the gene–e
Externí odkaz:
https://doaj.org/article/7fcae32543ce44f0b3f646c324ba17f9
Publikováno v:
Frontiers in Artificial Intelligence, Vol 6 (2024)
Human brain organoids, aka cerebral organoids or earlier “mini-brains”, are 3D cellular models that recapitulate aspects of the developing human brain. They show tremendous promise for advancing our understanding of neurodevelopment and neurologi
Externí odkaz:
https://doaj.org/article/c8365d4f096a47f98575bc59d8fa4099
Autor:
Thomas Hartung
Publikováno v:
Frontiers in Artificial Intelligence, Vol 6 (2023)
The rapid progress of AI impacts various areas of life, including toxicology, and promises a major role for AI in future risk assessments. Toxicology has shifted from a purely empirical science focused on observing chemical exposure outcomes to a dat
Externí odkaz:
https://doaj.org/article/c036e540ec1d4ae9a99c1bc47e0e7973
Autor:
Breanne Kincaid, Przemyslaw Piechota, Emily Golden, Mikhail Maertens, Thomas Hartung, Alexandra Maertens
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
Introduction: The positive identification of xenobiotics and their metabolites in human biosamples is an integral aspect of exposomics research, yet challenges in compound annotation and identification continue to limit the feasibility of comprehensi
Externí odkaz:
https://doaj.org/article/207d7747f34246498a9047f51f3b490a
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/47c6271053ce45d183bc5a3bbeb34f95