Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Thomas, Hünig"'
Autor:
Mohammad Badr, Rhonda L. McFleder, Jingjing Wu, Susanne Knorr, James B. Koprich, Thomas Hünig, Jonathan M. Brotchie, Jens Volkmann, Manfred B. Lutz, Chi Wang Ip
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-19 (2022)
Abstract Background Regulatory CD4+CD25+FoxP3+ T cells (Treg) are a subgroup of T lymphocytes involved in maintaining immune balance. Disturbance of Treg number and impaired suppressive function of Treg correlate with Parkinson’s disease severity.
Externí odkaz:
https://doaj.org/article/ded71ba65a6c4640bc37adca0c1102e3
Autor:
Eva Wagner-Drouet, Daniel Teschner, Christine Wolschke, Dietlinde Janson, Kerstin Schäfer-Eckart, Johannes Gärtner, Stephan Mielke, Martin Schreder, Guido Kobbe, Mustafa Kondakci, Inken Hilgendorf, Marie von Lilienfeld-Toal, Stefan Klein, Daniela Heidenreich, Sebastian Kreil, Mareike Verbeek, Sandra Grass, Markus Ditschkowski, Tanja Gromke, Martina Koch, Monika Lindemann, Thomas Hünig, Traudel Schmidt, Anne Rascle, Harald Guldan, Sascha Barabas, Ludwig Deml, Ralf Wagner, Daniel Wolff
Publikováno v:
Haematologica, Vol 106, Iss 2 (2019)
Recurrence of cytomegalovirus reactivation remains a major cause of morbidity and mortality following allogeneic hematopoietic stem cell transplantation. Monitoring cytomegalovirus-specific cellular immunity using a standardized assay might improve t
Externí odkaz:
https://doaj.org/article/7480ee8f27644c2597b4e8a470fe521f
Autor:
Daniela Langenhorst, Stephanie Haack, Selina Göb, Anna Uri, Fred Lühder, Bernard Vanhove, Thomas Hünig, Niklas Beyersdorf
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Compared to naive T cells, differentiated T cells are thought to be less dependent on CD28 costimulation for full activation. To revisit the role of CD28 costimulation in mouse T cell recall responses, we adoptively transferred in vitro generated OT-
Externí odkaz:
https://doaj.org/article/aa89dd6fa47043779ab56e35c4c363df
Autor:
Daniela Langenhorst, Paula Tabares, Tobias Gulde, Bryan R. Becklund, Susanne Berr, Charles D. Surh, Niklas Beyersdorf, Thomas Hünig
Publikováno v:
Frontiers in Immunology, Vol 8 (2018)
In rodents, low doses of CD28-specific superagonistic monoclonal antibodies (CD28 superagonists, CD28SA) selectively activate regulatory T cells (Treg). This observation has recently been extended to humans, suggesting an option for the treatment of
Externí odkaz:
https://doaj.org/article/803c85bb94f64da7b18c609ea251a7cd
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Acute graft-versus-host disease (aGvHD) is a major cause of morbidity and mortality after allogeneic hematopoietic stem cell plus T cell transplantation (allo-HSCT). In this study, we investigated the requirement for CD28 co-stimulation of donor CD4+
Externí odkaz:
https://doaj.org/article/3be9a0af23fd4797a29a9d8d8bbc4a3d
Autor:
Arne Bergfeld, Prasad Dasari, Sandra Werner, Timothy R. Hughes, Wen-Chao Song, Peter Hortschansky, Axel A. Brakhage, Thomas Hünig, Peter F. Zipfel, Niklas Beyersdorf
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Opportunistic infections with the saprophytic yeast Candida albicans are a major cause of morbidity in immunocompromised patients. While the interaction of cells and molecules of innate immunity with C. albicans has been studied to great depth, compa
Externí odkaz:
https://doaj.org/article/4c324c2666984feb96ae92c5be9ab06e
Autor:
Valérie Boivin, Niklas Beyersdorf, Dieter Palm, Viacheslav O Nikolaev, Angela Schlipp, Justus Müller, Doris Schmidt, Vladimir Kocoski, Thomas Kerkau, Thomas Hünig, Georg Ertl, Martin J Lohse, Roland Jahns
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117589 (2015)
Despite recent therapeutic advances the prognosis of heart failure remains poor. Recent research suggests that heart failure is a heterogeneous syndrome and that many patients have stimulating auto-antibodies directed against the second extracellular
Externí odkaz:
https://doaj.org/article/bb5ce71e88f645a2baaa41e4f4e365b5
Autor:
Hlumani Ndlovu, Mathew Darby, Monika Froelich, William Horsnell, Fred Lühder, Thomas Hünig, Frank Brombacher
Publikováno v:
PLoS Pathogens, Vol 10, Iss 2, p e1003906 (2014)
IL-13 driven Th2 immunity is indispensable for host protection against infection with the gastrointestinal nematode Nippostronglus brasiliensis. Disruption of CD28 mediated costimulation impairs development of adequate Th2 immunity, showing an import
Externí odkaz:
https://doaj.org/article/262ee9bad83e469f8f886607c34e116b
Publikováno v:
Clinical and Developmental Immunology, Vol 8, Iss 1, Pp 19-30 (2000)
Externí odkaz:
https://doaj.org/article/5cc879091ab24804b07e4655b37f038c
Autor:
Marie von Lilienfeld-Toal, Christine Wolschke, Traudel Schmidt, Sebastian Kreil, Kerstin Schäfer-Eckart, Daniel Teschner, Ludwig Deml, Martina Koch, Harald Guldan, Tanja Gromke, Stefan Klein, Mareike Verbeek, Stephan Mielke, Mustafa Kondakci, Monika Lindemann, Martin Schreder, Ralf Wagner, Sandra Grass, Dietlinde Janson, Guido Kobbe, Anne Rascle, Eva Maria Wagner-Drouet, Johannes Gärtner, Inken Hilgendorf, Daniela Heidenreich, Sascha Barabas, Markus Ditschkowski, Thomas Hünig, Daniel Wolff
Publikováno v:
Haematologica
Recurrence of cytomegalovirus reactivation remains a major cause of morbidity and mortality following allogeneic hematopoietic stem cell transplantation. Monitoring cytomegalovirus-specific cellular immunity using a standardized assay might improve t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca6bf053e495b9d42a9d0ec5b443777
https://epub.uni-regensburg.de/45155/
https://epub.uni-regensburg.de/45155/
