Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Thomas, Eiermann"'
Publikováno v:
Trends in Genetics. 37:784-797
Human leukocyte antigen (HLA)-encoded surface molecules present antigenic peptides to T lymphocytes and play a key role in adaptive immune responses. Besides their physiological role of defending the host against infectious pathogens, specific allele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b9703831bf296679fa8f8314128728
https://doi.org/10.1016/j.tig.2021.04.012
https://doi.org/10.1016/j.tig.2021.04.012
Autor:
Tobias Deuse, Mandy Stubbendorff, Karis Tang-Quan, Neil Phillips, Mark A. Kay, Thomas Eiermann, Thang T. Phan, Hans-Dieter Volk, Hermann Reichenspurner, Robert C. Robbins, Sonja Schrepfer M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 20 (2011)
We here present an immunologic head-to-head comparison between human umbilical cord lining mesenchymal stem cells (clMSCs) and adult bone marrow MSCs (bmMSCs) from patients >65 years of age. clMSCs had significantly lower HLA class I expression, high
Externí odkaz:
https://doaj.org/article/287f0b6740294c8292602f8dac6c2e9e
Autor:
Djordje Atanackovic, Yanran Cao, Tim Luetkens, Jens Panse, Christiane Faltz, Julia Arfsten, Katrin Bartels, Christine Wolschke, Thomas Eiermann, Axel R. Zander, Boris Fehse, Carsten Bokemeyer, Nicolaus Kroger
Publikováno v:
Haematologica, Vol 93, Iss 3 (2008)
Background Very little is known about the number and function of immunosuppressive CD4+CD25+FOXP3+ T regulatory cells (Treg) in the human bone marrow and it is unclear whether bone marrow-residing Treg are capable of regenerating following allogeneic
Externí odkaz:
https://doaj.org/article/6b53d947b8ac4595bb76f4217d428d7b
Autor:
Carolina Cruciani, Yingdong Zhao, Jian Wang, Lena Mühlenbruch, Wolfgang Faigle, William W. Kwok, Mathias Hauri-Hohl, Julie T. Nguyen, Mireia Sospedra, Roland Martin, Christian Münz, Ivan Jelcic, Magdalena Foege, Jar-How Lee, Veronika Haunerdinger, Andreas Lutterotti, Richard Reynolds, Nora C. Toussaint, Thomas Eiermann, Thomas M.C. Binder, Laura Fuentes-Font, Lennart Opitz, Hans-Georg Rammensee, Stefan Stevanovic, Reza Naghavian
Publikováno v:
Cell
1281.e20
Cell, 183 (5)
1281.e20
Cell, 183 (5)
Summary The HLA-DR15 haplotype is the strongest genetic risk factor for multiple sclerosis (MS), but our understanding of how it contributes to MS is limited. Because autoreactive CD4+ T cells and B cells as antigen-presenting cells are involved in M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97f4709d306b5c8706129b252ef08c64
http://europepmc.org/articles/PMC7707104
http://europepmc.org/articles/PMC7707104
Autor:
Reinhard Kelsch, Julia M. Wikner, Thomas Eiermann, Peter Kühnl, Ulrich Finckh, Cornelia Brendel, Lilian Aly, Ina Alster, Thomas M.C. Binder
Publikováno v:
Human Immunology. 76:124-128
The HLA-DR and -DQ loci are close neighbors on chromosome 6 that are highly linked. Many common associations between HLA-DR and DQ-alleles are known, normally transmitted as HLA-DR̃DQ haplotypes from one generation to another. Reports of very recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc0dcf9933d6b7e222de468a7a68f2c
https://doi.org/10.1016/j.humimm.2015.01.016
https://doi.org/10.1016/j.humimm.2015.01.016
Autor:
Anja Lehnhardt, Matthias Marget, Friedrich Thaiss, Thomas Eiermann, Martina Koch, Maximiliane Strecker, Björn Nashan
Publikováno v:
Clinical Transplantation. 29:359-364
B cells and their regulation by B-cell activating factor BAFF are of growing interest in kidney transplantation (KTx). There is evidence that high serum (s) BAFF leads to increased allosensitization and impaired long-term graft function. We prospecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685939e11d36666a6202e15695997c2a
https://doi.org/10.1111/ctr.12523
https://doi.org/10.1111/ctr.12523
Autor:
Christoph Sarrazin, Jörg Timm, Robert Thimme, Arthur Y. Kim, John Sidney, Thomas Kuntzen, Silvana Gaudieri, K. Nitschke, Christoph Neumann-Haefelin, Alejandro Barriga, Daniel López, Georg M. Lauer, Todd M. Allen, Thomas Eiermann, Alessandro Sette, Christian M. Lange, Andri Rauch, Julia Schmidt, Sergei Viazov
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
ResearcherID
Instituto de Salud Carlos III (ISCIII)
ResearcherID
HLA-B*27 is associated with spontaneous HCV genotype 1 clearance. HLA-B*27-restricted CD8+ T cells target three NS5B epitopes. Two of these epitopes are dominantly targeted in the majority of HLA-B*27+ patients. In chronic infection, viral escape occ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54ea0b51f0386ed497159d2e5730c72
https://doi.org/10.1016/j.jhep.2013.08.009
https://doi.org/10.1016/j.jhep.2013.08.009
Autor:
Thomas Eiermann, Jan van Lunzen, V Matzat, Clara Lehmann, Olaf Degen, Ansgar W. Lohse, Philip Hartjen, Anh Q. Le, I Tóth, Claudia Beisel, Dirk Meyer-Olson, Adriana Thomssen, Joachim Hauber, Maximilian Bockhorn, Gerd Fätkenheuer, C Scheurich, Julian Schulze zur Wiesch, Philipp Busch
Publikováno v:
Journal of Leukocyte Biology. 94:551-561
Recent studies indicate that murine Tregs highly express the ENTDP1, as well as the 5′-NT and thereby, suppress Teff function by extracellular adenosine production. Furthermore, CD73 seems to play a role as costimulatory molecule for T cell differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59507655b4d64850481521a76ade7b32
https://doi.org/10.1189/jlb.0113018
https://doi.org/10.1189/jlb.0113018
Autor:
Karen Bieback, Mandy Stubbendorff, Hans-Dieter Volk, Xiaoqin Hua, Tobias Deuse, Sonja Schrepfer, Thomas Eiermann, Kerry Atkinson, Hermann Reichenspurner, Joachim Velden, Thang T. Phan, Robert C. Robbins, Christine Schröder
Publikováno v:
Stem Cells and Development. 22:2619-2629
Mesenchymal stromal cells (MSCs) have been isolated from many tissues, including gestational tissue. To date, a study comparing the properties and suitability of these cells in cell-based therapies is lacking. In this study, we compared the phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd9c84b5f4ba7b7d8a1779c542ba866
https://doi.org/10.1089/scd.2013.0043
https://doi.org/10.1089/scd.2013.0043
Autor:
Jar-How Lee, Thomas M.C. Binder, Stefan Stevanovic, Michal J. Okoniewski, Hans-Georg Rammensee, Thomas Eiermann, Roland Martin, Christian Hotz, Mireia Sospedra, Malte Mohme
Publikováno v:
Brain. 136:1783-1798
The HLA-DR15 haplotype confers the largest part of the genetic risk to develop multiple sclerosis, a prototypic CD4+ T cell-mediated autoimmune disease. The mechanisms how certain HLA-class II molecules functionally contribute to autoimmune diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dcb32d68d3162dfa76863d78cd0bd63
https://doi.org/10.1093/brain/awt108
https://doi.org/10.1093/brain/awt108