Zobrazeno 1 - 10
of 288
pro vyhledávání: '"Thomas, Deller"'
Autor:
Sharif Jabra, Michael Rietsche, Julia Muellerleile, Aet O’Leary, David A. Slattery, Thomas Deller, Meike Fellenz
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Sex hormones affect structural and functional plasticity in the rodent hippocampus. However, hormone levels not only differ between males and females, but also fluctuate across the female estrous cycle. While sex- and cycle-dependent differe
Externí odkaz:
https://doaj.org/article/a00f61bd05ab439c90ea83286867f95e
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Quantitative PCR (qPCR) is a widely used method to study gene expression changes following brain injury. The accuracy of this method depends on the tissue harvested, the time course analyzed and, in particular on the choice of appropriate in
Externí odkaz:
https://doaj.org/article/9fb6bb1680314087860d1b0cc43c03e3
Autor:
Nina Rößler, Tassilo Jungenitz, Albrecht Sigler, Alexander Bird, Martin Mittag, Jeong Seop Rhee, Thomas Deller, Hermann Cuntz, Nils Brose, Stephan W. Schwarzacher, Peter Jedlicka
Publikováno v:
Open Biology, Vol 13, Iss 8 (2023)
Dendritic spines are crucial for excitatory synaptic transmission as the size of a spine head correlates with the strength of its synapse. The distribution of spine head sizes follows a lognormal-like distribution with more small spines than large on
Externí odkaz:
https://doaj.org/article/bd78c7109d364e9c9d436be340b75e5d
Autor:
Domenico Del Turco, Mandy H. Paul, Jessica Schlaudraff, Julia Muellerleile, Fran Bozic, Mario Vuksic, Peter Jedlicka, Thomas Deller
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
The cation-chloride cotransporters KCC2 and NKCC1 regulate the intracellular Cl− concentration and cell volume of neurons and/or glia. The Cl− extruder KCC2 is expressed at higher levels than the Cl− transporter NKCC1 in mature compared to imma
Externí odkaz:
https://doaj.org/article/3c711dbf82f943d394fc8e79d70c0ebe
Autor:
Tassilo Jungenitz, Alexander Bird, Maren Engelhardt, Peter Jedlicka, Stephan W. Schwarzacher, Thomas Deller
Publikováno v:
Frontiers in Neuroanatomy, Vol 17 (2023)
The axon initial segment (AIS) is the site of action potential initiation and important for the integration of synaptic input. Length and localization of the AIS are dynamic, modulated by afferent activity and contribute to the homeostatic control of
Externí odkaz:
https://doaj.org/article/db502a10667946dfb9a06d1c1d87e54c
Autor:
Conrad C. Prillwitz, Bastian David, Gottfried Schlaug, Thomas Deller, Johannes Schramm, Robert Lindenberg, Elke Hattingen, Bernd Weber, Rainer Surges, Christian E. Elger, Theodor Rüber
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 9, Pp 1796-1808 (2021)
Abstract Objective Using multimodal imaging, we tested the hypothesis that patients after hemispherotomy recruit non‐primary motor areas and non‐pyramidal descending motor fibers to restore motor function of the impaired limb. Methods Functional
Externí odkaz:
https://doaj.org/article/248cf770f9dd43a0b0802f6650e038fe
All-trans retinoic acid induces synaptopodin-dependent metaplasticity in mouse dentate granule cells
Autor:
Maximilian Lenz, Amelie Eichler, Pia Kruse, Julia Muellerleile, Thomas Deller, Peter Jedlicka, Andreas Vlachos
Publikováno v:
eLife, Vol 10 (2021)
Previously we showed that the vitamin A metabolite all-trans retinoic acid (atRA) induces synaptic plasticity in acute brain slices prepared from the mouse and human neocortex (Lenz et al., 2021). Depending on the brain region studied, distinct effec
Externí odkaz:
https://doaj.org/article/fb7d9b3f4220485cb150ebb0c9125ac4
Autor:
Mandy H. Paul, Lars Hildebrandt-Einfeldt, Viktor J. Beeg Moreno, Domenico Del Turco, Thomas Deller
Publikováno v:
Frontiers in Neuroanatomy, Vol 15 (2021)
Sprouting of surviving axons is one of the major reorganization mechanisms of the injured brain contributing to a partial restoration of function. Of note, sprouting is maturation as well as age-dependent and strong in juvenile brains, moderate in ad
Externí odkaz:
https://doaj.org/article/41791f0c17534653827371d5e506f1b0
Autor:
Maximilian Lenz, Pia Kruse, Amelie Eichler, Jakob Straehle, Jürgen Beck, Thomas Deller, Andreas Vlachos
Publikováno v:
eLife, Vol 10 (2021)
A defining feature of the brain is the ability of its synaptic contacts to adapt structurally and functionally in an experience-dependent manner. In the human cortex, however, direct experimental evidence for coordinated structural and functional syn
Externí odkaz:
https://doaj.org/article/36c5ffc4f8d341739403e75f7c1f5ec0
Autor:
Lars Hildebrandt-Einfeldt, Kenrick Yap, Mandy H. Paul, Carolin Stoffer, Nadine Zahn, Alexander Drakew, Maximilian Lenz, Andreas Vlachos, Thomas Deller
Publikováno v:
Frontiers in Neuroanatomy, Vol 15 (2021)
The entorhino-dentate projection, i.e., the perforant pathway, terminates in a highly ordered and laminated fashion in the rodent dentate gyrus (DG): fibers arising from the medial entorhinal cortex (MEC) terminate in the middle molecular layer, wher
Externí odkaz:
https://doaj.org/article/0493239372a345db97f1da749bc0679d