Glioma extracellular vesicles for precision medicine: prognostic and theragnostic application

Autor: Hany E. Marei, Asmaa Althani, Nahla Afifi, Anwarul Hasan, Thomas Caceci, Ingrid Cifola, Sara Caratelli, Giuseppe Sconocchia, Igea D’Agnano, Carlo Cenciarelli

Publikováno v: Discover Oncology, Vol 13, Iss 1, Pp 1-12 (2022)

Abstract EV produced by tumour cells carry a diverse population of proteins, lipids, DNA, and RNA molecules throughout the body and appear to play an important role in the overall development of the disease state, according to growing data. Gliomas a

Externí odkaz: https://doaj.org/article/e4a8f209c4104b86b08c0037bf0c96a9

p53 signaling in cancer progression and therapy

Autor: Hany E. Marei, Asmaa Althani, Nahla Afifi, Anwarul Hasan, Thomas Caceci, Giacomo Pozzoli, Andrea Morrione, Antonio Giordano, Carlo Cenciarelli

Publikováno v: Cancer Cell International, Vol 21, Iss 1, Pp 1-15 (2021)

Abstract The p53 protein is a transcription factor known as the "guardian of the genome" because of its critical function in preserving genomic integrity. The TP53 gene is mutated in approximately half of all human malignancies, including those of th

Externí odkaz: https://doaj.org/article/bfc96b4559ee4c3da63c2326d55a89a7

Generation of gene edited hiPSC from familial Alzheimer's disease patient carrying N141I missense mutation in presenilin 2

Autor: Hany E. Marei, Asmaa Althani, Nahla Afifi, Anwarul Hasan, Thomas Caceci, Giacomo Pozzoli, Carlo Cenciarelli

Publikováno v: Stem Cell Research, Vol 56, Iss , Pp 102552- (2021)

Alzheimer's disease (AD) is the major cause of dementia worldwide. Early-onset familial AD accounts for about 0.5% of all AD and is caused by single major gene mutations and autosomal dominant inheritance. An N141I missense mutation is associated wit

Externí odkaz: https://doaj.org/article/e99643c49aef47e1b09d079eb4502d3c

Effects of Rosemary Oil (Rosmarinus officinalis) supplementation on the fate of the transplanted human olfactory bulb neural stem cells against ibotenic acid-induced neurotoxicity (Alzheimer model) in rat

Autor: Samah Lashen, Shaymaa Rezk, Basma M. Hendam, Hany E. Marei, Mohamed El-Adl, Gehad E. Elshopakey, Thomas Caceci, Mona M. Elghareeb, Carlo CenciarelliC

Publikováno v: Metabolic brain disease (2022). doi:10.1007/s11011-021-00890-6
info:cnr-pdr/source/autori:Shaymaa Rezk, Samah Lashen, Mohamed El-Adl, Gehad E Elshopakey, Mona M Elghareeb, Basma M Hendam, Thomas Caceci, Carlo Cenciarelli, Hany E Marei/titolo:Effects of Rosemary Oil (Rosmarinus officinalis) supplementation on the fate of the transplanted human olfactory bulb neural stem cells against ibotenic acid-induced neurotoxicity (Alzheimer model) in rat/doi:10.1007%2Fs11011-021-00890-6/rivista:Metabolic brain disease/anno:2022/pagina_da:/pagina_a:/intervallo_pagine:/volume

Rosemary oil (ROO) is known to have multiple pharmacological effects: it is an antioxidant, anti-inflammatory, and cytoprotective. In the present study, we examined the effects of ROO on Human olfactory bulb neuronal stem cells (hOBNSCs) after their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a145f82d3fe070a455f017c85dd0df99
https://doi.org/10.1007/s11011-021-00890-6

Effects of Rosemary Oil (Rosmarinus officinalis) supplementation on the fate of the transplanted human olfactory bulb neural stem cells against ibotenic acid-induced neurotoxicity (Alzheimer model) in rat

Autor: Shaymaa, Rezk, Samah, Lashen, Mohamed, El-Adl, Gehad E, Elshopakey, Mona M, Elghareeb, Basma M, Hendam, Thomas, Caceci, Carlo, Cenciarelli, Hany E, Marei

Publikováno v: Metabolic brain disease. 37(4)

Rosemary oil (ROO) is known to have multiple pharmacological effects: it is an antioxidant, anti-inflammatory, and cytoprotective. In the present study, we examined the effects of ROO on Human olfactory bulb neuronal stem cells (hOBNSCs) after their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::609d233bab38ea79e7438d96ee3301f3
https://pubmed.ncbi.nlm.nih.gov/35075502