Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Thomas, Balle"'
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1665 (2023)
Background: Pain can have a serious impact on a patient’s physical, mental, and social health, often causing their quality of life to decline. Various nicotine dosage forms, such as nicotine patches and nasal spray, have been developed and used as
Externí odkaz:
https://doaj.org/article/4fb4f8ee8b074bfeb44e44dabb74c169
Publikováno v:
Journal of Cheminformatics, Vol 13, Iss 1, Pp 1-13 (2021)
Abstract Motivation Ether-a-go-go-related gene (hERG) channel blockade by small molecules is a big concern during drug development in the pharmaceutical industry. Blockade of hERG channels may cause prolonged QT intervals that potentially could lead
Externí odkaz:
https://doaj.org/article/02726b731b5642b39af2693ea350e281
Autor:
Puja Bhattacharyya, Richard I. Christopherson, Kristen K. Skarratt, Jake Z. Chen, Thomas Balle, Stephen J. Fuller
Publikováno v:
Cancers, Vol 15, Iss 11, p 2881 (2023)
B cells are central to the adaptive immune response, providing long lasting immunity after infection. B cell activation is mediated by a cell surface B cell receptor (BCR) following recognition of an antigen. BCR signaling is modulated by several co-
Externí odkaz:
https://doaj.org/article/c966c232c40045efacd94f0abc22bce1
Publikováno v:
Molecules, Vol 28, Iss 10, p 4108 (2023)
Encephalopathies are brain dysfunctions that lead to cognitive, sensory, and motor development impairments. Recently, the identification of several mutations within the N-methyl-D-aspartate receptor (NMDAR) have been identified as significant in the
Externí odkaz:
https://doaj.org/article/89e51df75ec846df9552c04bc57ec3c9
Autor:
Abdul Karim, Vahid Riahi, Avinash Mishra, M. A. Hakim Newton, Abdollah Dehzangi, Thomas Balle, Abdul Sattar
Publikováno v:
ACS Omega, Vol 6, Iss 18, Pp 12306-12317 (2021)
Externí odkaz:
https://doaj.org/article/256523aa02464ee7b95cb2302c398ca9
Publikováno v:
Molecules, Vol 28, Iss 3, p 1324 (2023)
Central nervous system (CNS) disorders are a therapeutic area in drug discovery where demand for new treatments greatly exceeds approved treatment options. This is complicated by the high failure rate in late-stage clinical trials, resulting in exorb
Externí odkaz:
https://doaj.org/article/4b14fa7977734858a7b7bfaa8bfa1e4c
Autor:
Sophie K. F. De Salis, Lanxin Li, Zheng Chen, Kam Wa Lam, Kristen K. Skarratt, Thomas Balle, Stephen J. Fuller
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8174 (2022)
The P2X7 receptor (P2X7R) is an ATP-gated membrane ion channel that is expressed by multiple cell types. Following activation by extracellular ATP, the P2X7R mediates a broad range of cellular responses including cytokine and chemokine release, cell
Externí odkaz:
https://doaj.org/article/c6d721797ae74371b9ffe22eb4cfe700
Autor:
Yujia Luo, Thomas Balle
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 131:443-451
Publikováno v:
Li, L, Li, Z, Balle, T, Liu, G & Guo, Z 2023, ' Biosynthesis of pectic oligosaccharide-based amphiphiles as novel stabilizers of nanoemulsions by coupling enzymatic depolymerization with alkyl/alkenyl succinylation ', Food Hydrocolloids, vol. 139, 108574 . https://doi.org/10.1016/j.foodhyd.2023.108574
Pectic oligosaccharides (POS) are gaining increasing recognition as a novel kind of prebiotics. Here, a new multipurpose amphiphilic POS was synthesized by coupling pectinase-mediated depolymerization of citrus pectin with lipase-catalyzed alkyl succ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a324262ec2d7b7feb86f3b9b8a0fb5ef
https://pure.au.dk/portal/da/publications/biosynthesis-of-pectic-oligosaccharidebased-amphiphiles-as-novel-stabilizers-of-nanoemulsions-by-coupling-enzymatic-depolymerization-with-alkylalkenyl-succinylation(5455844b-e542-4ac1-914e-369fe6251281).html
https://pure.au.dk/portal/da/publications/biosynthesis-of-pectic-oligosaccharidebased-amphiphiles-as-novel-stabilizers-of-nanoemulsions-by-coupling-enzymatic-depolymerization-with-alkylalkenyl-succinylation(5455844b-e542-4ac1-914e-369fe6251281).html
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 12, Pp 29029-29046 (2015)
Stroke is one of the leading causes of death and long-term disability, with limited treatment options available. Inflammation contributes to damage tissue in the central nervous system across a broad range of neuropathologies, including Alzheimer’s
Externí odkaz:
https://doaj.org/article/023308ad431a4084ac1dd29b32ac1f42