Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Thokhir Basha Shaik"'
Autor:
Ahmed Kamal, Zaki S. Seddigi, Sunitha Rani, Thokhir Basha Shaik, M. Shaheer Malik, Ismail Althagafi
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 20:599-611
Background: Cancer is one of the major health and social-economic problems despite considerable progress in its early diagnosis and treatment. Owing to the emergence and increase of multidrug resistance to various conventional drugs, and the continui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4abc7ca78c2f1f0aad23140ad8f9c6ad
https://doi.org/10.2174/1871520620666191224122204
https://doi.org/10.2174/1871520620666191224122204
Autor:
Abdullah Alarifi, Ahmed Kamal, Syed Mohammed Ali Hussaini, B. Sridevi, Faria Sultana, Siddiq Pasha Shaik, Debanjan Bhattacharjee, Vadithe Lakshma Nayak, Kanakaraju Marumudi, Thokhir Basha Shaik
Publikováno v:
ChemistrySelect. 2:9901-9910
A series of 2-anilinopyridyl linked oxindole conjugates (6 a-ad) were synthesized andevaluated for their antiproliferative activity against a panel of four human cancer cell lines viz., HeLa, DU-145, A549 and MCF-7. All the compounds showed very good
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff54e07500bda49c8e279e51007eeb26
https://doi.org/10.1002/slct.201701787
https://doi.org/10.1002/slct.201701787
Autor:
Poornachandra Yedla, Korrapati Suresh Babu, Ganesh Kumar Chityal, Thokhir Basha Shaik, Ahmed Kamal, Syed Mohammed Ali Hussaini
Publikováno v:
Chemical Biology & Drug Design. 88:97-109
A series of pyrazoline derivatives and corresponding chalcone intermediates with substituents same as combretastatin-A4(CA-4) conjugated with triazole nucleus has been synthesized and evaluated for their anticancer potential. Sulphorhodamine B(SRB) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2148290faa5a0e6e6663b2b06a12474d
https://doi.org/10.1111/cbdd.12738
https://doi.org/10.1111/cbdd.12738
Autor:
S.M. Ali Hussaini, V. Lakshma Nayak, M. Shaheer Malik, M. Lakshmi Sucharitha, Thokhir Basha Shaik, Chandrakant Bagul, Ashraf, Ahmed Kamal
Publikováno v:
Bioorganic & Medicinal Chemistry. 22:6755-6767
A series of 2-anilinopyridine dimers have been synthesized and evaluated for their anticancer potential. Most of the compounds have showed significant growth inhibition of the cell lines tested and compound 4d was most effective amongst the series di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7560370ae577b52989357930aa8a8756
https://doi.org/10.1016/j.bmc.2014.11.001
https://doi.org/10.1016/j.bmc.2014.11.001
Cancer is one of the major health and social-economic problems despite considerable progress in its early diagnosis and treatment. Owing to the emergence and increase of multi drug resistance to various conventional drugs, and the continuing importan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e48ed46333978940221464a8f395c5c3
https://doi.org/10.1101/108654
https://doi.org/10.1101/108654
Autor:
Jedy Jose, Ahmed Kamal, Vadithe Lakshma Nayak, Korrapati Suresh Babu, Prema L. Mallipeddi, Kunta Chandra Shekar, Rasala Mahesh, Thokhir Basha Shaik, Syed Riyaz, Gajjela Bharth Kumar, Narayana Nagesh, Challa Ratna Reddy
Publikováno v:
ChemMedChem. 12(9)
Newer therapeutics can be developed in drug discovery by adopting the strategy of scaffold hopping of the privileged scaffolds from known bioactive compounds. This strategy has been widely employed in drug-discovery processes. Structure-based docking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d55be2a7affb56dc6ecef59f3e39b51d
https://pubmed.ncbi.nlm.nih.gov/28276645
https://pubmed.ncbi.nlm.nih.gov/28276645
Rational design and synthesis of 2-anilinopyridinyl-benzothiazole Schiff bases as antimitotic agents
Autor:
Ahmed Kamal, S.M. Ali Hussaini, Thokhir Basha Shaik, M. Shaheer Malik, M. Lakshmi Sucharitha, V. Lakshma Nayak
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(11)
Based on our previous results and literature precedence, a series of 2-anilinopyridinyl-benzothiazole Schiff bases were rationally designed by performing molecular modeling experiments on some selected molecules. The binding energies of the docked mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf069d3c59b04398d134b92c10a3aa5
https://pubmed.ncbi.nlm.nih.gov/28400235
https://pubmed.ncbi.nlm.nih.gov/28400235
Autor:
Satish Sunkari, T. Srinivasa Reddy, Siddiq Pasha Shaik, Thokhir Basha Shaik, A. Subba Rao, Chandrakant Bagul, V. Lakshma Nayak, Konderu Swapna, Ahmed Kamal
Publikováno v:
Bioorganicmedicinal chemistry. 25(3)
A series of colchicine site binding tubulin inhibitors were synthesized by the modification of the combretastatin pharmacophore. The ring B was replaced by the pharmacologically relevant benzothiazole scaffolds, and the cis configuration of the olefi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5708ef48111aa4e666210f9d5dd67c0
https://pubmed.ncbi.nlm.nih.gov/28034647
https://pubmed.ncbi.nlm.nih.gov/28034647
Autor:
Ahmed Kamal, Riyaz Syed, M.V.P.S. Vishnu Vardhan, Prema L. Mallipeddi, Md. Ashraf, Thokhir Basha Shaik, M. Shaheer Malik
Publikováno v:
Bioorganicmedicinal chemistry letters. 26(18)
A series of colchicine site binding tubulin inhibitors were designed and synthesized by the modification of the combretastatin A-4 (CA4) pharmacophore. The ring B was replaced by the pharmacologically relevant benzimidazole or benzothiazole scaffolds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6610ada1abd14398862c51ae7e33a7c
https://pubmed.ncbi.nlm.nih.gov/27515320
https://pubmed.ncbi.nlm.nih.gov/27515320
Autor:
Y. V. V. Srikanth, Thokhir Basha Shaik, Ahmed Kamal, Md. Ashraf, Shasi V. Kalivendi, M. Naseer A. Khan
Publikováno v:
Letters in Drug Design & Discovery. 9:242-250
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::162fea934e98fc26a650730ff2c92303
https://doi.org/10.2174/157018012799129774
https://doi.org/10.2174/157018012799129774