Zobrazeno 1 - 10 of 78 pro vyhledávání: '"Thohan, S"'
1
Akademický článek
Discovery of Darovasertib (NVP-LXS196), a Pan-PKC Inhibitor for the Treatment of Metastatic Uveal Melanoma.
Autor: Visser M; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Papillon JPN; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Luzzio M; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., LaMarche MJ; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Fan J; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Michael W; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Wang D; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Zhang A; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Straub C; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Mathieu S; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Kato M; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Palermo M; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Chen C; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Ramsey T; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Joud C; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Barrett R; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Vattay A; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Guo R; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Bric A; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Chung F; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Liang G; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Romanowski MJ; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Lam J; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Thohan S; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Atassi F; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Wylie A; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Cooke VG; Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2024 Jan 25; Vol. 67 (2), pp. 1447-1459. Date of Electronic Publication: 2024 Jan 10.
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2
Akademický článek
Effects of waterborne nitrite onphase I–II biotransformation in channel catfish( Ictalurus punctatus)
Autor: González, J.F, Del Valle, P.L, Thohan, S, Kane, A.S *
Publikováno v: In Marine Environmental Research 2000 50(1):29-32
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3
Akademický článek
The Safety and Antiviral Activity of BZF961 with or without Ritonavir in Patients Infected with Hepatitis C Virus: A Randomized, Multicenter Trial.
Autor: Lawitz E; Texas Liver Institute, University of Texas Health San Antonio, San Antonio, Texas., Bidair M; Alvarado Hospital Medical Center, San Diego, California., Marbury T; Orlando Clinical Research Center, Orlando, Florida., Jones CT; Novartis Institutes for BioMedical Research, Emeryville, California., Barve A; Novartis Pharmaceuticals, East Hanover, New Jersey., Magnusson B; Novartis Pharmaceuticals, Basel, Switzerland., Barkan DT; Novartis Institutes for BioMedical Research, Emeryville, California., Bodendorf U; Novartis Pharmaceuticals, Basel, Switzerland., Bracken K; Novartis Institute for BioMedical Research, Cambridge, Massachusetts., Canino E; Novartis Institutes for BioMedical Research, Emeryville, California., Chen D; Novartis Institutes for BioMedical Research, Emeryville, California., Dabovic K; Novartis Pharmaceuticals, East Hanover, New Jersey., Heimbach T; Novartis Pharmaceuticals, East Hanover, New Jersey., Ison M; Novartis Institutes for BioMedical Research, Emeryville, California., Jones CL; Novartis Institutes for BioMedical Research, Emeryville, California., Kovacs SJ; Novartis Institute for BioMedical Research, Cambridge, Massachusetts., Lakshman JP; Novartis Pharmaceuticals, East Hanover, New Jersey., Li B; Novartis Institute for BioMedical Research, Cambridge, Massachusetts., Raman P; Novartis Pharmaceuticals, East Hanover, New Jersey., Steiner-Swiat R; Novartis Pharmaceuticals, East Hanover, New Jersey., Thohan S; Novartis Institute for BioMedical Research, Cambridge, Massachusetts., Wong KA; Novartis Institutes for BioMedical Research, Emeryville, California., Zhong W; Novartis Institutes for BioMedical Research, Emeryville, California., Colvin RA; Novartis Institute for BioMedical Research, Cambridge, Massachusetts. Electronic address: richard.colvin@novartis.com.
Publikováno v: Clinical therapeutics [Clin Ther] 2018 Sep; Vol. 40 (9), pp. 1567-1581.e4. Date of Electronic Publication: 2018 Sep 02.
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4
Akademický článek
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5
Akademický článek
The allosteric inhibitor ABL001 enables dual targeting of BCR-ABL1.
Autor: Wylie AA; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, USA., Schoepfer J; Novartis Institutes for BioMedical Research, Basel, Switzerland., Jahnke W; Novartis Institutes for BioMedical Research, Basel, Switzerland., Cowan-Jacob SW; Novartis Institutes for BioMedical Research, Basel, Switzerland., Loo A; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, USA., Furet P; Novartis Institutes for BioMedical Research, Basel, Switzerland., Marzinzik AL; Novartis Institutes for BioMedical Research, Basel, Switzerland., Pelle X; Novartis Institutes for BioMedical Research, Basel, Switzerland., Donovan J; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, USA., Zhu W; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, USA., Buonamici S; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, USA., Hassan AQ; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, USA., Lombardo F; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, USA., Iyer V; Novartis Institutes for BioMedical Research, Basel, Switzerland., Palmer M; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, USA., Berellini G; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, USA., Dodd S; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, USA., Thohan S; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, USA., Bitter H; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, USA., Branford S; Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, South Australia 5000, Australia., Ross DM; Haematology Directorate, SA Pathology, PO Box 14, Rundle Mall, Adelaide, South Australia 5000, Australia., Hughes TP; South Australian Health &Medical Research Institute (SAHMRI), North Terrace, Adelaide, South Australia 5000, Australia., Petruzzelli L; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, USA., Vanasse KG; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, USA., Warmuth M; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, USA., Hofmann F; Novartis Institutes for BioMedical Research, Basel, Switzerland., Keen NJ; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, USA., Sellers WR; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, USA.
Publikováno v: Nature [Nature] 2017 Mar 30; Vol. 543 (7647), pp. 733-737. Date of Electronic Publication: 2017 Mar 22.
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6
Akademický článek
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7
Akademický článek
Integrating amino acids into Bcr-Abl inhibitors: design, synthesis, biological evaluation, and in silico studies.
Autor: Yuying Liu, Zeyu Yang, Jie Zhang, Na Guo, Nanxin Liu, Qingqing Zhang, Xintao Dang, Yanchen Li, Xiaoyan Pan
Publikováno v: RSC Medicinal Chemistry; Oct2024, Vol. 15 Issue 10, p3507-3528, 22p
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8
Akademický článek
Liver slice technology as an in vitro model for metabolic and toxicity studies.
Autor: Thohan S; Department of Drug Metabolism and Pharmacokinetics, Astra Zeneca, Waltham, MA, USA., Rosen GM
Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2002; Vol. 196, pp. 291-303.
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10
Akademický článek
3-Phosphoinositide-Dependent Kinase 1 as a Therapeutic Target for Treating Diabetes.
Autor: Xiang X; Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital and Yuying Childrens' Hospital of Wenzhou Medical University, Wenzhou, Zhejieng 325027, China.; Key Laboratory of Pediatric Anesthesiology, Ministry of Education, Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Anesthesiology of Zhejiang Province, Wenzhou Medical University, Wenzhou, Zhejieng 325027, China., Shuya P; Zhejiang Provincial Clinical Research Center for Obstetrics and Gynecology, Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejieng, China., Jiamin Z; Zhejiang Provincial Clinical Research Center for Obstetrics and Gynecology, Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejieng, China., Zihan Z; Zhejiang Provincial Clinical Research Center for Obstetrics and Gynecology, Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejieng, China., Xumei Y; Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital and Yuying Childrens' Hospital of Wenzhou Medical University, Wenzhou, Zhejieng 325027, China.; Key Laboratory of Pediatric Anesthesiology, Ministry of Education, Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Anesthesiology of Zhejiang Province, Wenzhou Medical University, Wenzhou, Zhejieng 325027, China., Jingjin L; Department of Cardiology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong, China.
Publikováno v: Current diabetes reviews [Curr Diabetes Rev] 2025; Vol. 21 (4), pp. 47-56.
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