Zobrazeno 1 - 10
of 154
pro vyhledávání: '"This Month in JoVE"'
Publikováno v:
J Vis Exp
The epigenetic transcription regulation mediated by 5-methylcytosine (5mC) has played a critical role in eukaryotic development. Demethylation of these epigenetic marks is accomplished by sequential oxidation by ten-eleven translocation dioxygenases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2175ab7412d266634f0d5f174ae323e
https://doi.org/10.3791/57798-v
https://doi.org/10.3791/57798-v
Publikováno v:
Journal of visualized experiments : JoVE. (139)
Binary transcription systems are powerful genetic tools widely used for visualizing and manipulating cell fate and gene expression in specific groups of cells or tissues in model organisms. These systems contain two components as separate transgenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6339ae8a3cfafef71c25b6398bd3be1a
https://pubmed.ncbi.nlm.nih.gov/30295654
https://pubmed.ncbi.nlm.nih.gov/30295654
Autor:
Mclaughlan, JR
Publikováno v:
Journal of Visualized Experiments : JoVE
In this study, plasmonic gold nanoparticles were simultaneously exposed to pulsed near-infrared laser light and high intensity focused ultrasound (HIFU) for the controllable nucleation of cavitation in tissue-mimicking gel phantoms. This in vitro pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a4cf4e5ebbacebfbafb241129f33ed0
https://doi.org/10.3791/58045
https://doi.org/10.3791/58045
Autor:
John Caufield, Wei Wang, Anders O. Garlid, David A. Liem, Karol E. Watson, Yijiang Zhou, Peipei Ping, Alex A. T. Bui
Publikováno v:
Journal of Visualized Experiments : JoVE
Clinical case reports (CCRs) are a valuable means of sharing observations and insights in medicine. The form of these documents varies, and their content includes descriptions of numerous, novel disease presentations and treatments. Thus far, the tex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ccb017fced43c3d97ba01efc377fcd8
https://doi.org/10.3791/58392-v
https://doi.org/10.3791/58392-v
Autor:
Michael Wilschanski, George M. Solomon, Paola Melotti, Kathryn Hayes, Steven M. Rowe, Isabelle Sermet-Gaudelus, Inez Bronsveld
Publikováno v:
Jove-Journal of visualized experiments, 2018(139). MYJoVE Corporation
George Solomon, Inez Bronsveld & Hayes, K 2018, ' Standardized Measurement of Nasal Membrane Transepithelial Potential Difference (NPD) ', Journal of visualized experiments : JoVE, vol. 139, no. e57006 . https://doi.org/10.3791/57006
George Solomon, Inez Bronsveld & Hayes, K 2018, ' Standardized Measurement of Nasal Membrane Transepithelial Potential Difference (NPD) ', Journal of visualized experiments : JoVE, vol. 139, no. e57006 . https://doi.org/10.3791/57006
We describe a standardized measurement of nasal potential difference (NPD). In this technique, cystic fibrosis transmembrane conductance regulator (CFTR) and the epithelial sodium channel (ENaC) function are monitored by the change in voltage across
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316df09dab3932eb876bc6acf1353bcf
https://doi.org/10.3791/57006
https://doi.org/10.3791/57006
Autor:
Wenfeng, Xia, Simeon J, West, Malcolm C, Finlay, Rosalind, Pratt, Sunish, Mathews, Jean-Martial, Mari, Sebastien, Ourselin, Anna L, David, Adrien E, Desjardins
Publikováno v:
Journal of Visualized Experiments : JoVE
Ultrasound is frequently used for guiding minimally invasive procedures, but visualizing medical devices is often challenging with this imaging modality. When visualization is lost, the medical device can cause trauma to critical tissue structures. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b89afc3d6b574bf52d0e3e299c71c7dc
https://pubmed.ncbi.nlm.nih.gov/30199033
https://pubmed.ncbi.nlm.nih.gov/30199033
Autor:
Paul Walther, Nicole L. Schieber, Inés Romero-Brey, Yannick Schwab, Claude Antony, Rachel Santarella-Mellwig, Uta Haselmann, Ralf Bartenschlager
Publikováno v:
Journal of Visualized Experiments : JoVE
Due to its high resolution, electron microscopy (EM) is an indispensable tool for virologists. However, one of the main difficulties when analyzing virus-infected or transfected cells via EM are the low efficiencies of infection or transfection, hind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::138f81986b81abdaf4ebe32011f166a8
http://europepmc.org/articles/PMC6235138
http://europepmc.org/articles/PMC6235138
Although over 200 genetic mutations in the human BEST1 gene have been identified and linked to retinal degenerative diseases, the pathological mechanisms remain elusive mainly due to the lack of a good in vivo model for studying BEST1 and its mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e526cfa12a10792f957080b8205f45ed
https://europepmc.org/articles/PMC6144140/
https://europepmc.org/articles/PMC6144140/
Autor:
Analía V. López, Daniel Hanley, Miri Dainson, Peter Samaš, Mark E. Hauber, Tomáš Grim, Lindsay Canniff
Publikováno v:
J Vis Exp
Brood parasites lay their eggs in other females' nests, leaving the host parents to hatch and rear their young. Studying how brood parasites manipulate hosts into raising their young and how hosts detect parasitism provide important insights in the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936b990782e753795ec7e5cd0ed6b40f
https://doi.org/10.3791/57512-v
https://doi.org/10.3791/57512-v
Publikováno v:
Journal of Visualized Experiments.
The mechanical properties of the nucleus determine its response to mechanical forces generated in cells. Because the nucleus is molecularly continuous with the cytoskeleton, methods are needed to probe its mechanical behavior in adherent cells. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1bee744724274f0193b66e7b4029e5
https://doi.org/10.3791/58038-v
https://doi.org/10.3791/58038-v