Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Thirushi P. Siriwardena"'
Autor:
Dana Yehudai, Sanduni U. Liyanage, Rose Hurren, Biljana Rizoska, Mark Albertella, Marcela Gronda, Danny V Jeyaraju, Xiaoming Wang, Samir H. Barghout, Neil MacLean, Thirushi P. Siriwardena, Yulia Jitkova, Paul Targett-Adams, Aaron D. Schimmer
Publikováno v:
Haematologica, Vol 104, Iss 5 (2019)
Mitochondrial DNA encodes 13 proteins that comprise components of the respiratory chain that maintain oxidative phosphorylation. The replication of mitochondrial DNA is performed by the sole mitochondrial DNA polymerase γ. As acute myeloid leukemia
Externí odkaz:
https://doaj.org/article/a3754aeeba0b4a40bc86a29f3f6df762
Autor:
Xiaoming Wang, Danny V. Jeyaraju, Marcela Gronda, Dana Yehudai, Sanduni U. Liyanage, Mark Albertella, Thirushi P. Siriwardena, Samir H. Barghout, Biljana Rizoska, Rose Hurren, Yulia Jitkova, Aaron D. Schimmer, Neil MacLean, Paul Targett-Adams
Publikováno v:
Haematologica
Mitochondrial DNA encodes 13 proteins that comprise components of the respiratory chain that maintain oxidative phosphorylation. The replication of mitochondrial DNA is performed by the sole mitochondrial DNA polymerase γ. As acute myeloid leukemia
Autor:
Rebecca R. Laposa, Dana Yehudai, Rose Hurren, Xiaoming Wang, Daina Avizonis, Gaëlle Bridon, Shrivani Sriskanthadevan, Aisha Shamas-Din, Mark D. Minden, Marcela Gronda, Veronique Voisin, Thirushi P. Siriwardena, Sanduni U. Liyanage, Changjiang Xu, Aaron D. Schimmer, Gary D. Bader, Neil MacLean
Publikováno v:
Blood. 129:2657-2666
Mitochondrial DNA (mtDNA) biosynthesis requires replication factors and adequate nucleotide pools from the mitochondria and cytoplasm. We performed gene expression profiling analysis of 542 human acute myeloid leukemia (AML) samples and identified 55
Autor:
Anna Rydlewski, Jaime O. Claudio, Karen Yee, Andre C. Schuh, Aaron D. Schimmer, Mahadeo A. Sukhai, Sanduni U. Liyanage, Thirushi P. Siriwardena, Mark D. Minden, Rose Hurren, Dawn Maze, Samir H. Barghout, Steven M. Chan, Amr Rostom, Hassan Sibai, Emily Heath, Dina Khalaf, Vikas Gupta, Marcela Gronda, Tracy Stockley, Tong Zhang, Andrzej Lutynski, Simon Kavanagh, Suzanne Kamel-Reid
Publikováno v:
Leukemia research. 68
We evaluated outcomes of 100 patients with high risk AML treated with Ida-FLAG induction as first-line therapy. 72 achieved remission with one cycle; 19 did not. High risk cytogenetics and TP53 mutations were associated with failure to achieve remiss
Autor:
Aniket Bankar, Rose Hurren, Sara Moses, Pedro Pinho, Helen Kylefjord, Paul Targett-Adams, Christina Rydergård, Richard Bethell, Anders Eneroth, Vilma Rraklli, Thirushi P. Siriwardena, Xiaoming Wang, Stefan Norin, Aaron D. Schimmer, Mark Albertella, Mark D. Minden, Simon Kavanagh, Johan Bylund, Biljana Rizoska
Publikováno v:
Blood. 132:3939-3939
The cytotoxic nucleoside cytarabine (Ara-C) is a cornerstone of AML induction and consolidation therapies, but drug resistance contributes to disease relapse. Among clinically relevant mechanisms of Ara-C resistance is the over-expression of cytidine
Autor:
Wang Xiaoming, Veronique Voisin, Changjiang Xu, Sanduni U. Liyanage, Gaëlle Bridon, Thirushi P. Siriwardena, Mark D. Minden, Gary D. Bader, Aisha Shamas-Din, Rose Hurren, Shrivani Sriskanthadevan, Rebecca R. Laposa, Neil MacLean, Aaron D. Schimmer
Publikováno v:
Blood. 128:1573-1573
Mitochondrial DNA (mtDNA) replication requires adequate nucleotide pools from the mitochondria and cytoplasm to support DNA biosynthesis. Gene expression profiling of 542 AML patient samples (GSE13159) demonstrated that 55% of AML patients had upregu
Autor:
Aniket Bankar, Thirushi Piyumika Siriwardena, Biljana Rizoska, Christina Rydergård, Helen Kylefjord, Vilma Rraklli, Anders Eneroth, Pedro Pinho, Stefan Norin, Johan Bylund, Sara Moses, Richard Bethell, Simon Kavanagh, Neil Maclean, Marcela Gronda, Xiaoming Wang, Rose Hurren, Mark D. Minden, Paul Targett-Adams, Aaron D. Schimmer, Mark Albertella
Publikováno v:
Haematologica, Vol 106, Iss 2 (2019)
Externí odkaz:
https://doaj.org/article/e6f9c4496da04b6c9457fce77c3e9d69