Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Thiruselvam Viswanathan"'
Autor:
Raja Veerapandian, Parveez Ahamed Abdul Azees, Thiruselvam Viswanathan, Bennett Tochukwu Amaechi, Govindsamy Vediyappan
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/27aeb2e759154cef8520d231ec7c4686
Autor:
Thiruselvam Viswanathan, Anurag Misra, Siu-Hong Chan, Shan Qi, Nan Dai, Shailee Arya, Luis Martinez-Sobrido, Yogesh K. Gupta
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
The SARS-CoV-2 nsp16/nsp10 enzyme complex methylates the 2′-OH of the first nucleotide of the viral mRNA, converting the Cap-0 to Cap-1, which helps the virus to evade immune surveillance in the host cell. Here, the authors present the crystal stru
Externí odkaz:
https://doaj.org/article/f218a0ba562445fea22bd96245c64491
Autor:
Thiruselvam Viswanathan, Shailee Arya, Siu-Hong Chan, Shan Qi, Nan Dai, Anurag Misra, Jun-Gyu Park, Fatai Oladunni, Dmytro Kovalskyy, Robert A. Hromas, Luis Martinez-Sobrido, Yogesh K. Gupta
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
Specific non-structural proteins (nsp) of SARS coronaviruses are involved in methylation of virally encoded mRNAs to mimic cellular mRNAs for protection against host innate immune restriction. Here, the authors present a high resolution structure of
Externí odkaz:
https://doaj.org/article/1a2c5dcfc62842e8b013e549e88fbd22
Publikováno v:
Molecular Microbiology. 119:505-514
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ea623ada1e10c5ddb0a498d7e2d1c49
https://doi.org/10.1111/mmi.15045
https://doi.org/10.1111/mmi.15045
Autor:
Padavattan, Sivaraman, Thiruselvam, Viswanathan, Shinagawa, Toshie, Hasegawa, Kazuya, Kumasaka, Takashi, Ishii, Shunsuke, Kumarevel, Thirumananseri
Publikováno v:
In Biophysical Chemistry February 2017 221:41-48
Publikováno v:
Environmental Science & Technology. 56:13858-13866
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b318f44709c1dceb03679172cdba1a4
https://doi.org/10.1021/acs.est.2c04324
https://doi.org/10.1021/acs.est.2c04324
Autor:
Shan Qi, Anurag Misra, Nan Dai, Yogesh K. Gupta, Shailee Arya, Luis Martinez-Sobrido, Thiruselvam Viswanathan, Siu-Hong Chan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
bioRxiv
article-version (status) pre
article-version (number) 1
bioRxiv
article-version (status) pre
article-version (number) 1
The SARS-CoV-2 nsp16/nsp10 enzyme complex modifies the 2′-OH of the first transcribed nucleotide of the viral mRNA by covalently attaching a methyl group to it. The 2′-O methylation of the first nucleotide converts the status of mRNA cap from Cap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c2663932c8d3be16894d12aa53d262b
https://doaj.org/article/f218a0ba562445fea22bd96245c64491
https://doaj.org/article/f218a0ba562445fea22bd96245c64491
Autor:
Anurag Misra, Nan Dai, Thiruselvam Viswanathan, Shan Qi, Yogesh K. Gupta, Luis Martinez-Sobrido, Siu-Hong Chan, Shailee Arya
The SARS-CoV-2 nsp16/nsp10 enzyme complex modifies the 2’-OH of the first transcribed nucleotide of the viral mRNA by covalently attaching a methyl group to it. The 2’-O methylation of the first nucleotide converts the status of mRNA cap from Cap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78176074992b4c35261eb87e3f40820d
https://doi.org/10.1101/2021.03.12.435174
https://doi.org/10.1101/2021.03.12.435174
Autor:
Shailee Arya, Shan Qi, Siu-Hong Chan, Fatai S. Oladunni, Robert Hromas, Luis Martinez-Sobrido, Thiruselvam Viswanathan, Jun Gyu Park, Nan Dai, Dmytro B. Kovalskyy, Anurag Misra, Yogesh K. Gupta
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
bioRxiv
article-version (status) pre
article-version (number) 1
Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
bioRxiv
article-version (status) pre
article-version (number) 1
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of COVID-19 illness, has caused millions of infections worldwide. In SARS coronaviruses, the non-structural protein 16 (nsp16), in conjunction with nsp10, methylate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1fc76808c05dc7fa99659360c432ee4
http://europepmc.org/articles/PMC7381649
http://europepmc.org/articles/PMC7381649
Autor:
Siu-Hong Chan, Jun Gyu Park, Robert Hromas, Luis Martinez-Sobrido, Nan Dai, Thiruselvam Viswanathan, Shan Qi, Shailee Arya, Fatai S. Oladunni, Yogesh K. Gupta
The novel severe acute respiratory syndrome coronoavirus-2 (SARS-CoV-2), the causative agent of COVID-19 illness, has caused over 2 million infections worldwide in four months. In SARS coronaviruses, the non-structural protein 16 (nsp16) methylates t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8d4f25a2a568c1ab29ca1369dadcc9
https://doi.org/10.1101/2020.04.26.061705
https://doi.org/10.1101/2020.04.26.061705