Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Thirumurugan Rathinasabapathy"'
Autor:
Chinmayee Panda, Thirumurugan Rathinasabapathy, Brandon Metzger, Sheila Dodson, Dirk Hanson, Jody Griffiths, Slavko Komarnytsky
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Lameness and restricted mobility are a significant concern in companion animals experiencing chronic pain, inflammation, or age-related pathologies. The growing awareness of health risks and side effects associated with the long-term use of prescript
Externí odkaz:
https://doaj.org/article/a9a9abaf624940deb149ecae133a2f1a
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 395 (2024)
Individuals who are overweight or obese are at increased risk of developing prediabetes and type 2 diabetes, yet the direct molecular mechanisms that connect diabetes to obesity are not clear. Chronic, sustained inflammation is considered a strong ri
Externí odkaz:
https://doaj.org/article/64f4bdef59e24288b12c10ed02ded1cc
Autor:
Thirumurugan Rathinasabapathy, Jade Lomax, Kavin Srikanth, Debora Esposito, Colin D. Kay, Slavko Komarnytsky
Publikováno v:
Immuno, Vol 2, Iss 2, Pp 293-306 (2022)
Wild blueberries (Vaccinium angustifolium Aiton.) are a rich source of dietary fiber and (poly)phenols with gastrointestinal and immune health-promoting properties, however, their mechanisms of action on the intestinal epithelial cells and transient
Externí odkaz:
https://doaj.org/article/16c3d9bb73e549a7809efb682daef686
Autor:
Edilane Rodrigues Dantas Araújo, Jacinthia Beatriz Xavier-Santos, Valéria Costa da Silva, Juliana Bessa Figueiredo de Lima, Jade Schlamb, Matheus de Freitas Fernandes-Pedrosa, Arnóbio Antônio da Silva Júnior, Raimundo Fernandes de Araújo Júnior, Thirumurugan Rathinasabapathy, Marvin Moncada, Debora Esposito, Gerlane Coelho Bernardo Guerra, Silvana Maria Zucolotto
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
Bryophyllumpinnatum (Crassulaceae) is used in traditional medicine for treating skin wounds. In our previous study, a topical gel containing B. pinnatum aqueous leaf extract showed a preclinical anti-inflammatory effect in in vivo acute edema models.
Externí odkaz:
https://doaj.org/article/c32d28c9b9ef4d6f94878ff4d3bbed5e
Autor:
Laura G. A. Esposito, Ezekial Overbaugh, Jia Xiong, Thirumurugan Rathinasabapathy, Slavko Komarnytsky, Derly José Henriques da Silva, Debora A. Esposito
Publikováno v:
Immuno, Vol 1, Iss 4, Pp 369-379 (2021)
Industrial hemp (Cannabis sativa L.) has many applications, including the production of textiles, agricultural extracts, nutritional products, and botanicals enriched with cannabinoids and full-spectrum terpenes naturally present in the plant. In thi
Externí odkaz:
https://doaj.org/article/8e7887b7378741f1af66bb37c6a5ae25
Autor:
Anik Boudreau, Alexander Poulev, David M. Ribnicky, Ilya Raskin, Thirumurugan Rathinasabapathy, Allison J. Richard, Jacqueline M. Stephens
Publikováno v:
Frontiers in Nutrition, Vol 6 (2019)
Adipocytes are important players in metabolic health and disease, and disruption of adipocyte development or function contributes to metabolic dysregulation. Hence, adipocytes are significant targets for therapeutic intervention in obesity and metabo
Externí odkaz:
https://doaj.org/article/c3af25eb727249a2b116743a69561123
Autor:
Thirumurugan Rathinasabapathy, Kimberly Marie Palatini Jackson, Yiwen Thor, Ayuba Sunday Buru, Debora Esposito, Xu Li, Mallikarjuna Rao Pichika, Ahmad Sazali Hamzah, Slavko Komarnytsky
Publikováno v:
Journal of Chemistry, Vol 2017 (2017)
Background. Glucocorticoid excess has been linked to clinical observations associated with the pathophysiology of metabolic syndrome. The intracellular glucocorticoid levels are primarily modulated by 11β-hydroxysteroid dehydrogenase type 1 (11β-HS
Externí odkaz:
https://doaj.org/article/d2322e16bf87477e88a0d38f6e77bb87
Publikováno v:
Journal of Agricultural and Food Chemistry. 70:2077-2091
Dietary intake of plant polyphenols is significant, and many of them enter a human body as a highly diverse pool of ring-fission phenolic metabolites arising from digestion and microbial catabolism of the parental structures. Difficulty in designing
Publikováno v:
Journal of agricultural and food chemistry. 70(7)
Respiratory viruses are linked to major epidemic events that have plagued humans through recorded history and possibly much earlier, ranging from common colds, influenza, and coronavirus infections to measles. However, difficulty in developing effect
Endocannabinoid System and Its Regulation by Polyunsaturated Fatty Acids and Full Spectrum Hemp Oils
Autor:
Charles Wagner, Sara Le Brun-Blashka, Slavko Komarnytsky, Carolina Carlisle, Thirumurugan Rathinasabapathy, Saradhadevi Varadharaj, Brandon Metzger, John P Troup, Chinmayee Panda
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 5479, p 5479 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 5479, p 5479 (2021)
The endocannabinoid system (ECS) consists of endogenous cannabinoids, their receptors, and metabolic enzymes that play a critical homeostatic role in modulating polyunsaturated omega fatty acid (PUFA) signaling to maintain a balanced inflammatory and