Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Thirumalai Ramalingam"'
Autor:
Zhonghan Yang, Viktoriya Grinchuk, Joseph F Urban, Jennifer Bohl, Rex Sun, Luigi Notari, Shu Yan, Thirumalai Ramalingam, Achsah D Keegan, Thomas A Wynn, Terez Shea-Donohue, Aiping Zhao
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59441 (2013)
Type 2 immunity is essential for host protection against nematode infection but is detrimental in allergic inflammation or asthma. There is a major research focus on the effector molecules and specific cell types involved in the initiation of type 2
Externí odkaz:
https://doaj.org/article/4901a0ced78f41729be0c6536d026844
Autor:
Robert W Thompson, John T Pesce, Thirumalai Ramalingam, Mark S Wilson, Sandy White, Allen W Cheever, Stacy M Ricklefs, Stephen F Porcella, Lili Li, Lesley G Ellies, Thomas A Wynn
Publikováno v:
PLoS Pathogens, Vol 4, Iss 3, p e1000023 (2008)
Cationic amino acid transporters (CAT) are important regulators of NOS2 and ARG1 activity because they regulate L-arginine availability. However, their role in the development of Th1/Th2 effector functions following infection has not been investigate
Externí odkaz:
https://doaj.org/article/c2010fd7023f4d37807348b4daa87aa2
Publikováno v:
Experimental Parasitology. 105:131-139
Eosinophilia in blood and tissues has been strongly associated with helminth infections for over a century. In vivo depletion of IL-5, a cytokine crucially involved in eosinophilopoiesis with an antibody or through genetic manipulation, reproducibly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690dbe8033590fa7c474f5731f375f86
https://doi.org/10.1016/j.exppara.2003.09.001
https://doi.org/10.1016/j.exppara.2003.09.001
Autor:
Daphne Macapagal, Jane Connor, Tomas Mikael Mustelin, Thirumalai Ramalingam, Thomas Wynn, Todd Davidson
Publikováno v:
The Journal of Immunology. 196:56.1-56.1
During sterile inflammatory reactions damage associated molecular patterns (DAMPS) are released from necrotic cells and recruit immune cells to the sites of tissue injury. We found that necrotic liver homogenates, when injected intraperitoneally, can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b473fe5827aea7424a71ac221ad3955
https://doi.org/10.4049/jimmunol.196.supp.56.1
https://doi.org/10.4049/jimmunol.196.supp.56.1
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 175(3)
We have previously shown that B cells (in particular B1 cells) are important in host protection against brugian infections in a murine i.p. model. In this study, we show that mice deficient in circulating IgM (secIgM−/−), but otherwise normal in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b470b6a6bcc9700374bd7076a32e0876
https://pubmed.ncbi.nlm.nih.gov/16034125
https://pubmed.ncbi.nlm.nih.gov/16034125
Filarial infections evoke exuberant inflammatory responses in the peritoneal cavities of immunocompetent mice. Clearance of infection appears to be dependent on complex interactions between B1 and B2 B lymphocytes, T cells, eosinophils, macrophages,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::907132b197cf1fc17336bd364507cbe3
https://europepmc.org/articles/PMC166020/
https://europepmc.org/articles/PMC166020/
Publikováno v:
Infection and Immunity. 73:8442-8443
The attenuation of eosinophilia by the administration of monoclonal antibodies to CCR3 consistently correlates with impairment in worm elimination following primary intraperitonealBrugia pahangiinfections in mice. Host protection was unimpaired in mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45839ee39fc0b862d85d54439a8b22df
https://doi.org/10.1128/iai.73.12.8442-8443.2005
https://doi.org/10.1128/iai.73.12.8442-8443.2005
Autor:
Yanfei Li, Anjiang Wang, Viktoriya Grinchuk, Allen Smith, Thirumalai Ramalingam, Thomas Wynn, Joseph Urban, Terez Shea-Donohue, Aiping Zhao
Publikováno v:
The Journal of Immunology. 190:136.17-136.17
IL-25 is a member of IL-17 cytokine family and is highly expressed in gastrointestinal epithelial cells. The biological activities of IL-25 have been associated with promotion of Th2 but inhibition of Th1/Th17 immunity. Whether IL-25 plays a role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e421db58b58cecf9dea61565de547b4f
https://doi.org/10.4049/jimmunol.190.supp.136.17
https://doi.org/10.4049/jimmunol.190.supp.136.17
Autor:
Thirumalai Ramalingam, Luke Barron, Margaret Mentink-Kane, Allen Cheever, Alison Humbles, Roland Kolbeck, Thomas Wynn
Publikováno v:
The Journal of Immunology. 186:58.9-58.9
The mouse Breast Regression Protein 39 (BRP39; Chi3l1) is a chitinase like protein but lacks enzymatic activity. Recently it was shown that mice lacking BRP39 displayed significantly impaired Th2 response during allergic airway disease. We sought to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b864a25c1a9973d06faf2f32ea58acb
https://doi.org/10.4049/jimmunol.186.supp.58.9
https://doi.org/10.4049/jimmunol.186.supp.58.9
Autor:
Thomas Wynn, Thirumalai Ramalingam, Satish Madala, Robert Thompson, Margaret Mentink, Luke Barron, Allen Cheever, Mark Wilson
Publikováno v:
The Journal of Immunology. 184:134.8-134.8
TH2 cytokines regulate inflammation, mucus production, tissue remodeling, and fibrosis. Consequently, they have become important therapeutic targets for a number of debilitating illnesses, including asthma, idiopathic pulmonary fibrosis, ulcerative c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a35713c61d6ab8256f27bea0139c404
https://doi.org/10.4049/jimmunol.184.supp.134.8
https://doi.org/10.4049/jimmunol.184.supp.134.8