Inhibiting Inducible Nitric Oxide Synthase with 1400W Reduces Soman (GD)-Induced Ferroptosis in Long-Term Epilepsy-Associated Neuropathology: Structural and Functional Magnetic Resonance Imaging Correlations with Neurobehavior and Brain Pathology.

Autor: Putra M; Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa (M.P., S.S.V., N.S.R., C.M., M.V.O., L.T., T.T.); Department of Radiology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa (D.R.T.); and Department of Radiology, Rutgers Biomedical and Health Sciences, New Jersey Medical School, Newark, New Jersey (S.S.K.)., Vasanthi SS; Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa (M.P., S.S.V., N.S.R., C.M., M.V.O., L.T., T.T.); Department of Radiology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa (D.R.T.); and Department of Radiology, Rutgers Biomedical and Health Sciences, New Jersey Medical School, Newark, New Jersey (S.S.K.)., Rao NS; Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa (M.P., S.S.V., N.S.R., C.M., M.V.O., L.T., T.T.); Department of Radiology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa (D.R.T.); and Department of Radiology, Rutgers Biomedical and Health Sciences, New Jersey Medical School, Newark, New Jersey (S.S.K.)., Meyer C; Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa (M.P., S.S.V., N.S.R., C.M., M.V.O., L.T., T.T.); Department of Radiology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa (D.R.T.); and Department of Radiology, Rutgers Biomedical and Health Sciences, New Jersey Medical School, Newark, New Jersey (S.S.K.)., Van Otterloo M; Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa (M.P., S.S.V., N.S.R., C.M., M.V.O., L.T., T.T.); Department of Radiology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa (D.R.T.); and Department of Radiology, Rutgers Biomedical and Health Sciences, New Jersey Medical School, Newark, New Jersey (S.S.K.)., Thangi L; Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa (M.P., S.S.V., N.S.R., C.M., M.V.O., L.T., T.T.); Department of Radiology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa (D.R.T.); and Department of Radiology, Rutgers Biomedical and Health Sciences, New Jersey Medical School, Newark, New Jersey (S.S.K.)., Thedens DR; Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa (M.P., S.S.V., N.S.R., C.M., M.V.O., L.T., T.T.); Department of Radiology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa (D.R.T.); and Department of Radiology, Rutgers Biomedical and Health Sciences, New Jersey Medical School, Newark, New Jersey (S.S.K.)., Kannurpatti SS; Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa (M.P., S.S.V., N.S.R., C.M., M.V.O., L.T., T.T.); Department of Radiology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa (D.R.T.); and Department of Radiology, Rutgers Biomedical and Health Sciences, New Jersey Medical School, Newark, New Jersey (S.S.K.)., Thippeswamy T; Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa (M.P., S.S.V., N.S.R., C.M., M.V.O., L.T., T.T.); Department of Radiology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa (D.R.T.); and Department of Radiology, Rutgers Biomedical and Health Sciences, New Jersey Medical School, Newark, New Jersey (S.S.K.) tswamy@iastate.edu.

Publikováno v: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2024 Jan 17; Vol. 388 (2), pp. 724-738. Date of Electronic Publication: 2024 Jan 17.

The NADPH Oxidase Inhibitor, Mitoapocynin, Mitigates DFP-Induced Reactive Astrogliosis in a Rat Model of Organophosphate Neurotoxicity.

Autor: Meyer C; Department of Biomedical Sciences, Iowa State University, Ames, IA 50010, USA., Grego E; Department of Chemical and Biological Engineering, Nanovaccine Institute, Iowa State University, Ames, IA 50011, USA., S Vasanthi S; Department of Biomedical Sciences, Iowa State University, Ames, IA 50010, USA., Rao NS; Department of Biomedical Sciences, Iowa State University, Ames, IA 50010, USA., Massey N; Department of Biomedical Sciences, Iowa State University, Ames, IA 50010, USA., Holtkamp C; Department of Biomedical Sciences, Iowa State University, Ames, IA 50010, USA., Huss J; Department of Biomedical Sciences, Iowa State University, Ames, IA 50010, USA., Showman L; W.M. Keck Metabolomics Research Laboratory, Iowa State University, Ames, IA 50011, USA., Narasimhan B; Department of Chemical and Biological Engineering, Nanovaccine Institute, Iowa State University, Ames, IA 50011, USA., Thippeswamy T; Department of Biomedical Sciences, Iowa State University, Ames, IA 50010, USA.

Publikováno v: Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2023 Nov 30; Vol. 12 (12). Date of Electronic Publication: 2023 Nov 30.

Exploring the benefits of in-diet versus repeated oral dosing of saracatinib (AZD0530) in chronic studies: insights into pharmacokinetics and animal welfare.

Autor: Vasanthi SS; Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA, United States., Massey N; Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA, United States., Nair SN; Department of Veterinary Pharmacology and Toxicology, College of Veterinary and Animal Sciences, Kerala Veterinary and Animal Sciences University, Thrissur, India., Mochel JP; Precision One Health, Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens, GA, United States., Showman L; W.M. Keck Metabolomics Research Laboratory, Iowa State University, Ames, IA, United States., Thippeswamy T; Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA, United States.

Publikováno v: Frontiers in veterinary science [Front Vet Sci] 2023 Nov 09; Vol. 10, pp. 1297221. Date of Electronic Publication: 2023 Nov 09 (Print Publication: 2023).

EVALUATION OF ANTICANCER POTENTIAL OF ETHANOLIC EXTRACT OF ALANGIUM SALVIFOLIUM LEAVES IN ANIMAL MODELS

Autor: Shashikumara Shashikumara, Prathima C, Thippeswamy T

Publikováno v: Asian Journal of Pharmaceutical and Clinical Research. :397-400

Objective: The present study aims to evaluate the anticancer potential of ethanolic extract of Alangium salvifolium leaves (EASL) against Ehrlich ascites carcinoma (EAC) in animal model. Methods: The ethanolic extract of A. salvifolium was prepared b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c494c56aebbbec8ebdce5e1f555a9e1
https://doi.org/10.22159/ajpcr.2019.v12i2.29601

Sex-based structural and functional MRI outcomes in the rat brain after soman (GD) exposure-induced status epilepticus.

Autor: Gage M; Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA., Vasanthi SS; Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA., Meyer CM; Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA., Rao NS; Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA., Thedens DR; Department of Radiology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, USA., Kannurpatti SS; Department of Radiology, Rutgers Biomedical and Health Sciences, New Jersey Medical School, Newark, New Jersey, USA., Thippeswamy T; Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA.

Publikováno v: Epilepsia open [Epilepsia Open] 2023 Jun; Vol. 8 (2), pp. 399-410. Date of Electronic Publication: 2023 Feb 06.