Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Thipparthi R. Reddy"'
Publikováno v:
Genes & Cancer. 3:177-186
Consumption of diets rich in fruits and vegetables is often associated with a reduced risk of developing cancer, particularly breast cancer. Considering that 1 in 8 women in the United States will develop breast cancer in the course of her lifetime,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a57da67c57417ed0b61078eee85eca9e
https://doi.org/10.1177/1947601912458581
https://doi.org/10.1177/1947601912458581
Publikováno v:
Journal of Cellular Physiology. 226:2747-2751
Sam68 (Src-associated protein in mitosis 68 kDa) is a multifunctional protein, known to govern cellular signal transduction, transcription, RNA metabolism, proliferation, apoptosis, and HIV-1 replication. Although intrinsic mechanisms that modulate S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be7b6d12fec4ff0adec61bd526e1e17b
https://doi.org/10.1002/jcp.22868
https://doi.org/10.1002/jcp.22868
Autor:
Thipparthi R. Reddy, Suhasini Modem
Publikováno v:
Journal of Cellular Physiology. 214:14-19
The human immunodeficiency virus type 1 (HIV-1) Rev protein facilitates the nuclear export of viral mRNA containing the Rev response element (RRE). Although several host proteins co-operating with Rev in viral RNA export have been reported, little is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac48070874ee3214ed6541420cbeca4
https://doi.org/10.1002/jcp.21305
https://doi.org/10.1002/jcp.21305
Publikováno v:
Nucleic Acids Research
Sam68 functionally complements for, as well as synergizes with, HIV-1 Rev in Rev response element (RRE)-mediated gene expression and virus production. Furthermore, C-terminal deletion/point mutants of Sam68 (Sam68DeltaC/Sam68-P21) exert a transdomina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f1435060112bedfab9cdc54875a2cb
https://doi.org/10.1093/nar/gki231
https://doi.org/10.1093/nar/gki231
Publikováno v:
Oncogene. 21:7187-7194
Sam68 is a target of the c-Src tyrosine kinase. We previously showed that overexpression of Sam68 functionally substitutes for, as well as synergies with, HIV-1 Rev in Rev-response element (RRE)-mediated gene expression and virus replication. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f8a286c384ee0961bce3773b87f7ce
https://doi.org/10.1038/sj.onc.1205759
https://doi.org/10.1038/sj.onc.1205759
Publikováno v:
Virology. 271:9-17
HIV-1 Nef interacts with cellular adaptor protein (AP) complexes and their medium (mu) subunits. However, the role of the dileucine-based sorting motif within Nef in these interactions has been incompletely characterized. Here, yeast two-hybrid assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4242f6a09de86bc6acf999c78573b38a
https://doi.org/10.1006/viro.2000.0277
https://doi.org/10.1006/viro.2000.0277
Autor:
Hengli Tang, Kenneth Frimpong, Christopher D. Goodwin, Jonathan K. L. Mau, Modem Suhasini, Flossie Wong-Staal, Thipparthi R. Reddy, David W. Rose, Weidong Xu
Publikováno v:
Nature Medicine. 5:635-642
The HIV-1 Rev protein facilitates the nuclear export of mRNA containing the Rev response element (RRE) through binding to the export receptor CRM-1. Here we show that a cellular nuclear protein, Sam68 (Src-associated protein in mitosis), specifically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c311fbc14206fdb9214a6fe943912c
https://doi.org/10.1038/9479
https://doi.org/10.1038/9479
Publikováno v:
Oncogene. 14:2785-2792
The Tax protein of the Human T-cell Leukemia Virus (HTLV) activates the expression of viral mRNA through a three 21 bp repeat enhancer located within the HTLV-1 LTR. Since Tax does not bind to the 21 bp DNA repeats directly, it has been speculated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe174fff90ee6115467ad17833f9d09a
https://doi.org/10.1038/sj.onc.1201119
https://doi.org/10.1038/sj.onc.1201119
Publikováno v:
Journal of Biomedical Science. 3:82-91
We have identified and obtained the full-length clone of RREBP49, a human nuclear factor which specifically interacts with the Rev-responsive element (RRE) sequence of human immunodeficiency virus type 1. Sequence analysis revealed that RREBP49 is hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a454b9d4ba74a84fd94b636a2d9b5ff0
https://doi.org/10.1007/bf02255535
https://doi.org/10.1007/bf02255535
Autor:
Thipparthi R. Reddy, Modem Suhasini
Publikováno v:
Current HIV research. 7(1)
The human immunodeficiency virus (HIV-1) differentially controls viral protein expression at the level of splicing as well as nuclear export of incompletely spliced viral RNA. This process, mediated by the Rev protein, interfaces with cellular compon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf60006816b6d04ffe26f30568a26ca
https://pubmed.ncbi.nlm.nih.gov/19149558
https://pubmed.ncbi.nlm.nih.gov/19149558