C21 preserves endothelial function in the thoracic aorta from DIO mice:role for AT2, Mas and B2 receptors

Autor: Marta Gil-Ortega, Beatriz Somoza, María S. Fernández-Alfonso, Marta Viana, M. Paz Lorenzo, Martín Alcalá, Thomas Unger, Raquel González-Blázquez, William A. Boisvert, Ulrike Muscha Steckelings

Publikováno v: González-Blázquez, R, Alcalá, M, Fernández-Alfonso, M S, Steckelings, U M, Lorenzo, M P, Viana, M, Boisvert, W, Unger, T, Ortega, M G & Somoza, B 2021, ' C21 preserves endothelial function in the thoracic aorta from DIO mice : role for AT2, Mas and B2 receptors ', Clinical Science, vol. 135, no. 9, pp. 1145-1163 . https://doi.org/10.1042/CS20210049
Clinical Science, 135(9), 1145-1163. Portland Press Ltd.

Compound 21 (C21), a selective agonist of angiotensin II type 2 receptor (AT2R), induces vasodilation through NO release. Since AT2R seems to be overexpressed in obesity, we hypothesize that C21 prevents the development of obesity-related vascular al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::877a98634f9c9ee846c5eeeae1f14062
https://portal.findresearcher.sdu.dk/da/publications/d3fcf2be-7770-4967-9d40-5384bb58c9fe

Prevention of diabetic nephropathy by compound 21, selective agonist of angiotensin type 2 receptors, in Zucker diabetic fatty rats

Autor: Cira Di Gioia, Raffaella Carletti, Silvia Maestroni, Thomas Unger, Giovanna Castoldi, C. Bombardi, Andrea Stella, Gianpaolo Zerbini, U. Muscha Steckelings, Björn Dahlöf

Publikováno v: Castoldi, G, di Gioia, C R, Bombardi, C, Maestroni, S, Carletti, R, Steckelings, U M, Dahlöf, B, Unger, T, Zerbini, G & Stella, A 2014, ' Prevention of diabetic nephropathy by compound 21, selective agonist of angiotensin type 2 receptors, in Zucker diabetic fatty rats ', American Journal of Physiology: Renal Physiology, vol. 307, no. 10, pp. F1123-F1131 . https://doi.org/10.1152/ajprenal.00247.2014
American Journal of Physiology-Renal Physiology, 307(10), F1123-F1131. American Physiological Society

The aim of this study was to evaluate the effect of compound 21 (C21), a selective AT2 receptor agonist, on diabetic nephropathy and the potential additive effect of C21, when associated with losartan treatment, on the development of albuminuria and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ae3004315f2ff815d8cad4b294592e2
https://doi.org/10.1152/ajprenal.00247.2014

Strontium Ranelate Treatment Improves Trabecular and Cortical Intrinsic Bone Tissue Quality, a Determinant of Bone Strength

Autor: Patrick Ammann, Sébastien Barraud, Romain Dayer, René Rizzoli, Isabelle Badoud

Publikováno v: Journal of Bone and Mineral Research, Vol. 22, No 9 (2007) pp. 1419-25

Beside its influence on determinants of bone strength (geometry, microarchitecture), which is likely to be related to a cellular effect, strontium ranelate improves bone tissue quality as evaluated by nanoindentation, increasing elastic modulus, hard

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5fe9aed3ec4fab89d8144b9fa5049ca
https://doi.org/10.1359/jbmr.070607

Comparing and contrasting the effects of strontium ranelate and other osteoporosis drugs on microarchitecture

Autor: Ferrari, Serge Livio

Publikováno v: Osteoporosis International, Vol. 21 Suppl 2 (2010) pp. S437-442

Altered bone microstructure is a major component of osteoporosis and bone fragility. Whilst an important standard by which to diagnose and make treatment decisions for osteoporosis, the evaluation of bone mineral mass by dual-energy X-ray absorptiome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1400::5b7c21e218871a99a954245b0c561007
https://archive-ouverte.unige.ch/unige:20930

Преимущества и риски позаскелетного действия кальция, витамина D и антиостеопоротических препаратов

Autor: Jean-Yves Reginster, Jean-Jacques Body, Jean-Pierre Devogelaer, Jean-Marc Kaufman, Serge Rozenberg, Evelien Gielen, Steven Boonen, Stefan Goemaere, Pierre Bergmann

Publikováno v: PAIN. JOINTS. SPINE; № 2.10 (2013); 11-21
Боль. Суставы. Позвоночник-Bolʹ, sustavy, pozvonočnik; № 2.10 (2013); 11-21
Біль. Суглоби. Хребет-Bolʹ, sustavy, pozvonočnik; № 2.10 (2013); 11-21
Bolʹ, Sustavy, Pozvonočnik, Vol 3, Iss 1.09, Pp 18-24 (2013)
PAIN. JOINTS. SPINE; № 1.09 (2013); 18-24
Боль. Суставы. Позвоночник-Bolʹ, sustavy, pozvonočnik; № 1.09 (2013); 18-24
Біль. Суглоби. Хребет-Bolʹ, sustavy, pozvonočnik; № 1.09 (2013); 18-24
Osteoporosis International
Bolʹ, Sustavy, Pozvonočnik, Vol 3, Iss 2.10, Pp 11-21 (2013)
Osteoporosis international, 23 Suppl 1

Drugs used for the prevention and the treatment of osteoporosis exert various favourable and unfavourable extra-skeletal effects whose importance is increasingly recognized notably for treatment selection.
Journal Article
Research Support,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f673d820abe4fb14e9e0fc5259261af8