Výsledky vyhledávání - "Thionucleotides/pharmacology"

Interaction of glibenclamide and metformin at the level of translation in pancreatic β cells

Autor: Ying Cai, Daniel Pipeleers, Zhidong Ling, Qidi Wang, Mark Van de Casteele

Sulfonylurea and metformin are used in the treatment of diabetes. Their chronic effects on β cells are not well known. We have shown that sustained exposure of rat β cells to glibenclamide increased their protein synthesis activity, while metformin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::513af24816a97ec2b45caf3d0350a9e2
https://hdl.handle.net/20.500.14017/c650d543-ae4e-46a1-be79-1cfa9eb8cccd

Zobrazit plný text záznamu

The oxytocin-induced inward current in vagal neurons of the rat is mediated by G protein activation but not by an increase in the intracellular calcium concentration

Autor: Jean Jacques Dreifuss, Mario Raggenbass, Stefano Alberi

Publikováno v: European Journal of Neuroscience, Vol. 9, No 12 (1997) pp. 2605-2612

The neuropeptide oxytocin can depolarize parasympathetic preganglionic neurons in the dorsal motor nucleus of the vagus nerve of the rat by generating a sustained inward current, which is sodium-dependent and tetrodotoxin-insensitive. The second mess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4dea4205900da36dd7b65b3d184c78
https://archive-ouverte.unige.ch/unige:10157

Zobrazit plný text záznamu

Preparations of Rp-cyclic adenosine 3',5'-phosphorothioate (Rp-cAMPS) can contain biologically active amounts of adenosine

Autor: Hans G. Genieser, Ian F. Musgrave, Roland Seifert, E. Maronde

Superoxide anion (O2-.) production from human neutrophils stimulated by N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP, 1 microM) was inhibited by preparations of the inhibitor of cAMP-dependent protein kinase, Rp-cyclic adenosine 3',5'-phosphor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991fd54f47836c2258e1fdf00dbe812d
https://epub.uni-regensburg.de/23290/

Zobrazit plný text záznamu

Extracellular calcium exerts a dual effect on renin secretion from isolated mouse juxtaglomerular cells

Autor: Armin Kurtz, R. Della Bruna, Karin Schricker

Utilizing primary cultures of mouse renal juxtaglomerular cells we found that renin secretion during 20 h of incubation was stimulated by 100% when extracellular calcium was lowered from a basal level of 0.5 mM to below 1 microM, and was enhanced in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d737fa5b81515d31b5244178207549d4

Zobrazit plný text záznamu

Guanine nucleotides stimulate NADPH oxidase in membranes of human neutrophils

Autor: Roland Seifert, Günter Schultz, Walter Rosenthal

Publikováno v: FEBS Letters. 205:161-165

In the chain of events by which chemotactic peptides stimulate NADPH oxidase-catalyzed superoxide formation in human neutrophils, the involvements of a pertussis toxin-sensitive guanine nucleotide-binding protein (N-protein), mobilization of intracel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e5cf57352b9e02dc331c142aa115d6
https://doi.org/10.1016/0014-5793(86)80886-9

Zobrazit plný text záznamu

Differential expression of cytosolic activation factors for NADPH oxidase in HL-60 leukemic cells

Autor: Roland Seifert, Günter Schultz, Peter Jungblut

Publikováno v: Biochemical and biophysical research communications. 161(3)

Activation of NADPH oxidase in undifferentiated HL-60 leukemic cells and in HL-60 cells differentiated along the myeloid pathway with dibutyryl cyclic AMP (dbcAMP) or dimethyl sulfoxide (Me2SO) was studied. Upon stimulation with a calcium ionophore,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99eca7ff25b3c7e2b0ef8874ccf2f407
https://pubmed.ncbi.nlm.nih.gov/2472788

Zobrazit plný text záznamu

Fatty-acid-induced activation of NADPH oxidase in plasma membranes of human neutrophils depends on neutrophil cytosol and is potentiated by stable guanine nucleotides

Autor: Günter Schultz, Roland Seifert

Both cis and trans unsaturated fatty acids and sodium dodecyl sulfate activated NADPH oxidase in plasma membranes of human neutrophils in the presence of neutrophil cytosol. In contrast, 5,8,11,14-icosatetraynoic acid, saturated fatty acids, esters,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575b9d6d4f08ddc0766df2724b97aa7e
https://epub.uni-regensburg.de/23273/

Zobrazit plný text záznamu

The role of nucleoside-diphosphate kinase reactions in G protein activation of NADPH oxidase by guanine and adenine nucleotides

Autor: Günter Schultz, Walter Rosenthal, Thomas Wieland, Peter Gierschick, Roland Seifert, Karl H. Jakobs

NADPH-oxidase-catalyzed superoxide (O2-) formation in membranes of HL-60 leukemic cells was activated by arachidonic acid in the presence of Mg2+ and HL-60 cytosol. The GTP analogues, guanosine 5'-[gamma-thio]triphosphate (GTP[gamma S] and guanosine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa904e9a145103198764e3f05ab49175
https://epub.uni-regensburg.de/23267/

Zobrazit plný text záznamu

The regulation of store-dependent Ca2+ influx in HL-60 granulocytes involves GTP-sensitive elements

Autor: Marisa Jaconi, Daniel Pablo Lew, Karl-Heinz Krause, Antoinette Monod

Publikováno v: Europe PubMed Central
Journal of Biological Chemistry, Vol. 268, No 35 (1993) pp. 26075-26078

In granulocytes, emptying of intracellular Ca2+ stores activates Ca2+ influx across the plasma membrane. To study the putative role of GTP-binding proteins in this process, we have introduced non-hydrolyzable guanosine phosphate analogues into the cy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9d6567a2e15e705b4cde6b136bb6914
http://europepmc.org/abstract/med/8253721

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání