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pro vyhledávání: '"Thiobutabarbital"'
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Publikováno v:
Magnetic Resonance in Medicine. 78:1136-1146
Purpose Anesthesia is a major confounding factor in functional MRI (fMRI) experiments attributed to its effects on brain function. Recent evidence suggests that parameters obtained with resting-state fMRI (rs-fMRI) are coupled with anesthetic depth.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4df8607f7c6c26312d1b7fc5e1960c2
https://doi.org/10.1002/mrm.26496
https://doi.org/10.1002/mrm.26496
Autor:
Artem Shatillo, Johanna Närväinen, Markus M. Forsberg, Olli Gröhn, Jaakko Paasonen, Raimo A. Salo, Joanna K. Huttunen
Publikováno v:
Paasonen, J, Salo, R A, Shatillo, A, Forsberg, M M, Närväinen, J, Huttunen, J K & Gröhn, O 2016, ' Comparison of seven different anesthesia protocols for nicotine pharmacologic magnetic resonance imaging in rat ', European Neuropsychopharmacology, vol. 26, no. 3, pp. 518-531 . https://doi.org/10.1016/j.euroneuro.2015.12.034
Pharmacologic MRI (phMRI) is a non-invasive in vivo imaging method, which can evaluate the drug effects on the brain and provide complementary information to ex vivo techniques. The preclinical phMRI studies usually require anesthesia to reduce the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718924ef1aaa1378078533d2a3833f1e
https://doi.org/10.1016/j.euroneuro.2015.12.034
https://doi.org/10.1016/j.euroneuro.2015.12.034
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 37:1170-1175
Summary 1. Urotensin-II (U-II) is a vasoactive peptide that influences renal haemodynamics and kidney function. The aim of the present study was to examine the effects of the selective U-II receptor antagonist, urantide, on renal haemodynamics, oxyge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acb5766ce7bb8569b4f980cd0fbd9596
https://doi.org/10.1111/j.1440-1681.2010.05449.x
https://doi.org/10.1111/j.1440-1681.2010.05449.x
Publikováno v:
Biological and Pharmaceutical Bulletin. 32:1924-1927
Ibudilast (3-isobutyryl-2-isopropylpyrazolo[1,5-alpha]pyridine) is clinically used as a cerebral vasodilator in Japan. However, the effects of ibudilast on retinal blood vessels have not been fully examined. The aim of this study, therefore, was to e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b708bc0ba88ff77b12ca9190c1905e1
https://doi.org/10.1248/bpb.32.1924
https://doi.org/10.1248/bpb.32.1924
Publikováno v:
Upsala Journal of Medical Sciences. 113:47-56
BACKGROUND: Repeated administration of glucose in vivo leads to a time-dependent potentiation of insulin release. Glucose is also known to stimulate pancreatic islet blood flow, but whether this is associated with a time-dependent potentiation is unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7e1e44ac675518998745850890313f0
https://doi.org/10.3109/2000-1967-213
https://doi.org/10.3109/2000-1967-213
Autor:
Kenji Sakamoto, Maki Saito, Asami Mori, Naoto Ogawa, Kunio Ishii, Sokichi Kametaka, Tsutomu Nakahara
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 375:323-328
We examined the effect of nicorandil on retinal blood vessels in rats in vivo. Male Wistar rats (8 to 10 weeks old) were anaesthetised with thiobutabarbital (120 mg/kg, intraperitoneal). Fundus images were captured with a digital camera that was equi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a4e7c87e4df6232177a0cf5cc50143
https://doi.org/10.1007/s00210-007-0165-7
https://doi.org/10.1007/s00210-007-0165-7
Publikováno v:
British Journal of Pharmacology. 143:371-378
Selegiline is used for treating Parkinson's disease. Despite its efficacy, the clinical use of selegiline in combination with l-dihydroxphenylalanine in Parkinsonian patients is hampered by cardiovascular complications, such as hypotension. This stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::019c26217de6e9715f384360598c758c
https://doi.org/10.1038/sj.bjp.0705962
https://doi.org/10.1038/sj.bjp.0705962
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 370:320-323
Mice that lack or over-express a gene of interest are important tools for unraveling gene function. The determination of single nephron function by micropuncture or precise determination of glomerular filtration rate (GFR) by inulin clearance method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6038ef3a4651179a40a81169555f73ce
https://doi.org/10.1007/s00210-004-0982-x
https://doi.org/10.1007/s00210-004-0982-x
Publikováno v:
Japanese Journal of Pharmacology. 85:241-249
Administration of bacterial endotoxin (lipopolysaccharide, LPS) intravenously has been noted to produce a shock state, which is characterized by hypotension and multi-organ system failure. The aim of the present investigation was to (a) examine the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2389093f0854ff3cf5299236459f99db
https://doi.org/10.1254/jjp.85.241
https://doi.org/10.1254/jjp.85.241