The Toxoplasma gondii effector GRA83 modulates the host’s innate immune response to regulate parasite infection

Autor: Thind, Amara C., Mota, Caroline M., Gonçalves, Ana Paula N., Sha, Jihui, Wohlschlegel, James A., Mineo, Tiago W.P., Bradley, Peter J.

Publikováno v: bioRxiv

Toxoplasma gondii ’s propensity to infect its host and cause disease is highly dependent on its ability to modulate host cell functions. One of the strategies the parasite uses to accomplish this is via the export of effector proteins from the secr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a780d32205d6a0e62c5e879e8137cc1a
https://europepmc.org/articles/PMC10312501/

The Toxoplasma gondii effector GRA83 modulates the host's innate immune response to regulate parasite infection.

Autor: Thind AC; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles , Los Angeles, California, USA.; Molecular Biology Institute, University of California, Los Angeles , Los Angeles, California, USA., Mota CM; Laboratory of Immunoparasitology 'Dr. Mário Endsfeldz Camargo,' Institute of Biomedical Sciences, Federal University of Uberlândia , Uberlândia, Minas Gerais, Brazil., Gonçalves APN; Laboratory of Immunoparasitology 'Dr. Mário Endsfeldz Camargo,' Institute of Biomedical Sciences, Federal University of Uberlândia , Uberlândia, Minas Gerais, Brazil., Sha J; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles , Los Angeles, California, USA., Wohlschlegel JA; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles , Los Angeles, California, USA., Mineo TWP; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles , Los Angeles, California, USA.; Laboratory of Immunoparasitology 'Dr. Mário Endsfeldz Camargo,' Institute of Biomedical Sciences, Federal University of Uberlândia , Uberlândia, Minas Gerais, Brazil., Bradley PJ; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles , Los Angeles, California, USA.; Molecular Biology Institute, University of California, Los Angeles , Los Angeles, California, USA.

Publikováno v: MSphere [mSphere] 2023 Oct 24; Vol. 8 (5), pp. e0026323. Date of Electronic Publication: 2023 Sep 28.