Zobrazeno 1 - 10 of 21 pro vyhledávání: '"Thimo L"'
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Generics' Appeal to Innovative Pharma
Autor: Thimo L. Sommerfeld
Publikováno v: Journal of Generic Medicines: The Business Journal for the Generic Medicines Sector. 4:259-266
Selling innovative drugs and generic drugs is as different as selling rockets and sneakers. It is, therefore, not surprising that innovative pharma companies have difficulties in developing strategies for entering and exploiting selected generic mark
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2774e00366c656cdda223c6f7c53599b
https://doi.org/10.1057/palgrave.jgm.4950077
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3
Private Equity's Growing role in the Generics Industry
Autor: Thimo L. Sommerfeld
Publikováno v: Journal of Generic Medicines: The Business Journal for the Generic Medicines Sector. 3:30-37
Private equity plays an increasingly important role in a number of industries. Early-stage (‘venture capital’) investors have been active in the biotech industry for a long time. Most late-stage (‘buyout’) investors, however, have steered cle
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d9f85caf586cf02ff56f79148b8c6da
https://doi.org/10.1057/palgrave.jgm.4940096
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4
Strategic Options for Mid-Sized Generics Players
Autor: Thimo L. Sommerfeld
Publikováno v: Journal of Generic Medicines: The Business Journal for the Generic Medicines Sector. 2:308-315
As generics markets are becoming more mature, size is playing an increasingly important role. Larger companies and niche players may be able to sustain their profitability by making adjustments to their operations, but mid-sized competitors see their
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5364d9df4413dc599df7d4d68c8a9b9a
https://doi.org/10.1057/palgrave.jgm.4940083
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5
Preparation of Oxazolidine-Containing Peptides: Unusual effects in RhIII-catalyzed acetalizations of aldehydes with urethane-protected serine and threonine esters and with dipeptides containing serine or threonine residues at the N-terminus
Autor: Luigi M. Venanzi, Dieter Seebach, Qiongzhong Jiang, Thimo L. Sommerfeld
Publikováno v: Helvetica Chimica Acta. 77:1313-1330
The cyclization reaction of aldehydes with Z- and Boc-protected β-hydroxyamino-acid esters (Tables 1 and 2), or of dipeptides containing serine or threonine at the N-terminus (Table 3), to give oxazolidine derivatives, occurs in the presence of isop
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::68235bf45d0c81340d0a09fef739108b
https://doi.org/10.1002/hlca.19940770513
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6
Dehydroalanine-Containing Peptides by AcOH-Elimination fromO-Acetylserine Residuces with DBU/LiClO4 in Tetrahydrofuran
Autor: Dieter Seebach, Thimo L. Sommerfeld
Publikováno v: Helvetica Chimica Acta. 76:1702-1714
The elimination of H2O from serine residues in peptides was found to be feasible by the following two steps: O-acylation with AcCl/pyrideine in CH2Cl2 and treatment with an imidine base (DBU or DBN) in THF in the presence of large amounts of LiClO4 (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4fee9a91ed8f4ec58c7abb77f53630a6
https://doi.org/10.1002/hlca.19930760427
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ChemInform Abstract: Preparation of Oxazolidine-Containing Peptides: Unusual Effects in RhIII-Catalyzed Acetalizations of Aldehydes with Urethane-Protected Serine and Threonine Esters and with Dipeptides Containing Serine or Threonine Residues at the N-Te
Autor: Dieter Seebach, Qiongzhong Jiang, Thimo L. Sommerfeld, Luigi M. Venanzi
Publikováno v: ChemInform. 25
The cyclization reaction of aldehydes with Z- and Boc-protected β-hydroxyamino-acid esters (Tables 1 and 2), or of dipeptides containing serine or threonine at the N-terminus (Table 3), to give oxazolidine derivatives, occurs in the presence of isop
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::47fa5e777048d36ec1eec8d13e93a537
https://doi.org/10.1002/chin.199452227
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A Highly Convergent Total Synthesis of (+)-Myxovirescine M2. Preliminary Communication
Autor: Geo Adam, Axel Neidlein, Dieter Seebach, Michael Sefkow, Francine Sternleld, Miguel A. Maestro, Thimo L. Sommerfeld
Publikováno v: Helvetica Chimica Acta. 74:2112-2118
The antibiotic myxovirescine M2 was synthesized from seven building blocks (1–7, Scheme 1), with the following chiral starting materials being employed: (S)-malic acid, (+)-D-ribonolactone, (S)-2-(hydroxymethyl)butanoate, and (2R,4S)-5-hydroxy-2,4-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::387f3d8b9e3ed9a0820dc8c45db6bbc1
https://doi.org/10.1002/hlca.19910740846
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