Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Thilo Spruß"'
Autor:
Rui Sun, Jia Le Lin, Man Si Cheng, Kang Yi Lee, Thilo Spruss, Christa Buechler, Herbert Schwarz
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2610 (2022)
Chemerin is a multifunctional adipokine that regulates adipogenesis, insulin signaling and blood pressure and has thus a central function in metabolism. Mounting evidence confirmed a function of chemerin in various cancers. In this study, we investig
Externí odkaz:
https://doaj.org/article/2e4fb153e9b047eda8db5689340c9340
Autor:
Lisa Schindler, Jutta Moosbauer, Daniel Schmidt, Thilo Spruss, Lukas Grätz, Steffen Lüdeke, Frank Hofheinz, Sebastian Meister, Bernd Echtenacher, Günther Bernhardt, Jens Pietzsch, Dirk Hellwig, Max Keller
Publikováno v:
Cancers; Volume 14; Issue 19; Pages: 4922
Cancers 14(2022), 4922
Cancers 14(2022), 4922
Overexpression of the neurotensin receptor type 1 (NTS1R), a peptide receptor located at the plasma membrane, has been reported for a variety of malignant tumors. Thus, targeting the NTS1R with 18F- or 68Ga-labeled ligands is considered a straightfor
Autor:
Jennifer Schmidt, Alexander Riechers, Raphael Stoll, Thomas Amann, Florian Fink, Thilo Spruss, Wolfram Gronwald, Burkhard König, Claus Hellerbrand, Anja Katrin Bosserhoff
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37941 (2012)
Melanoma is the most aggressive form of skin cancer, with fast progression and early dissemination mediated by the melanoma inhibitory activity (MIA) protein. Here, we discovered that dimerization of MIA is required for functional activity through mu
Externí odkaz:
https://doaj.org/article/39e4ad3f93ac47aba5e3380637e30990
Publikováno v:
Oncogene. 37:897-911
Malignant melanoma reveals rapidly increasing incidence and mortality rates worldwide. By now, BRAF inhibition is the standard therapy for advanced melanoma in patients carrying BRAF mutations. However, only approximately 50% of melanoma patients har
Publikováno v:
Otologyneurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 40(5)
Hypothesis: The choice of the material for plugging a dehiscence of the superior semicircular canal is based on the ease of use and the success of the procedure to permanently relieve symptoms without adverse side effects. Background: Dehiscence of t
Publikováno v:
Pigment cellmelanoma research. 31(5)
The network of molecular players is similar when comparing neural crest-derived, actively migrating melanoblasts to melanoma cells. However, melanoblasts are sensitive to differentiation-initiating signals at their target site (epidermis), while mela
Autor:
Judith Dierlamm, Estefanía Rodríguez, Thomas Speiseder, Thomas Dobner, Nuray Akyüz, Helga Hofmann-Sieber, Thilo Spruss, Anna Schellenberg, Claudia Lange
Publikováno v:
Journal of virology. 91(1)
Previous observations that human amniotic fluid cells (AFC) can be transformed by human adenovirus type 5 (HAdV-5) E1A/E1B oncogenes prompted us to identify the target cells in the AFC population that are susceptible to transformation. Our results de
Autor:
O. Stöltzing, Hannah Wagner, R Dayoub, Hans-Jürgen Schlitt, Thilo Spruss, Christa Buechler, Frauke Bataille, Thomas S. Weiss
Publikováno v:
Molecular Medicine. 17:221-228
Augmenter of liver regeneration (ALR), which is critically important in liver regeneration and hepatocyte proliferation, is highly expressed in cirrhotic livers and hepatocellular carcinomas (HCC). In the current study, the functional role of ALR in
Autor:
Anja-Katrin Bosserhoff, Erwin Gäbele, T. Amann, Thilo Spruss, Frauke Bataille, Marcus Mühlbauer, Jürgen Schölmerich, P. Kiefer, Claus Hellerbrand
Publikováno v:
Cancer Science. 100:646-653
Liver cirrhosis is the main risk factor for the development of hepatocellular carcinoma (HCC). Activated hepatic stellate cells (HSC) are the effector cells of hepatic fibrosis and also infiltrate the HCC stroma where they might play a critical role
Autor:
Anna K. Seitz, Achim Goepferich, Lukas Prantl, Joerg Tessmar, Torsten Blunk, Claudia Fischbach-Teschl, Thilo Spruss, Thomas Schubert, Johannes Zellner, Barbara Weiser
Publikováno v:
Tissue Engineering Part A. 14:275-284
One strategy of adipose tissue engineering is to transplant adipocytes or adipocyte precursor cells in combination with polymeric materials. However, a satisfying formation of fat tissue and its long-term survival still remain major problems. There i