Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Thilo, van Eimeren"'
Autor:
Verena Dzialas, Merle C. Hoenig, Stéphane Prange, Gérard N. Bischof, the Parkinson’s Progression Marker Initiative, Alexander Drzezga, Thilo van Eimeren
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Resilience in neuroscience generally refers to an individual’s capacity to counteract the adverse effects of a neuropathological condition. While resilience mechanisms in Alzheimer’s disease are well-investigated, knowledge regarding its
Externí odkaz:
https://doaj.org/article/6670e329cb2c466388f32386778e75eb
Autor:
Javier Oltra, Barbara Segura, Antonio P. Strafella, Thilo van Eimeren, Naroa Ibarretxe-Bilbao, Maria Diez-Cirarda, Carsten Eggers, Olaia Lucas-Jiménez, Gemma C. Monté-Rubio, Natalia Ojeda, Javier Peña, Marina C. Ruppert, Roser Sala-Llonch, Hendrik Theis, Carme Uribe, Carme Junque
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Clinical, cognitive, and atrophy characteristics depending on sex have been previously reported in Parkinson’s disease (PD). However, though sex differences in cortical gray matter measures in early drug naïve patients have been described
Externí odkaz:
https://doaj.org/article/203a4637f4aa464796e4c107d5a3541e
Autor:
Hendrik Theis, Stéphane Prange, Gérard N. Bischof, Merle C. Hoenig, Marc Tittgemeyer, Lars Timmermann, Gereon R. Fink, Alexander Drzezga, Carsten Eggers, Thilo van Eimeren
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-7 (2023)
Abstract Impulsive-compulsive behaviour (ICB) is a frequently observed non-motor symptom in early Parkinson’s disease after initiating dopamine replacement therapy. At the opposite end of the motivated behaviour spectrum, apathy occurs in early Par
Externí odkaz:
https://doaj.org/article/d8b9f2365bfd433eb5435de244ce6a9f
Autor:
Karima Chakroun, Antonius Wiehler, Ben Wagner, David Mathar, Florian Ganzer, Thilo van Eimeren, Tobias Sommer, Jan Peters
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Dopamine fundamentally contributes to reinforcement learning, but recent accounts also suggest a contribution to specific action selection mechanisms and the regulation of response vigour. Here, we examine dopaminergic mechanisms underlying
Externí odkaz:
https://doaj.org/article/6fb6176da3044439b1fa6b57fcb8cae7
Autor:
Kenan Steidel, Marina C. Ruppert, Andrea Greuel, Masoud Tahmasian, Franziska Maier, Jochen Hammes, Thilo van Eimeren, Lars Timmermann, Marc Tittgemeyer, Alexander Drzezga, David J. Pedrosa, Carsten Eggers
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract The prevailing network perspective of Parkinson’s disease (PD) emerges not least from the ascending neuropathology traceable in histological studies. However, whether longitudinal in vivo correlates of network degeneration in PD can be obs
Externí odkaz:
https://doaj.org/article/4d234eb6376f41a088bf43bcbd4572ba
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-8 (2021)
Abstract Impulse-control disorders are commonly observed during dopamine-replacement therapy in Parkinson’s disease, but the majority of patients seems “immune” to this side effect. Epidemiological evidence suggests that a major risk factor may
Externí odkaz:
https://doaj.org/article/6568bcc4d3d74378b5a605904e087140
Publikováno v:
Brain Sciences, Vol 12, Iss 9, p 1248 (2022)
The limbic system describes a complex of brain structures central for memory, learning, as well as goal directed and emotional behavior. In addition to pathological studies, recent findings using in vivo structural and functional imaging of the brain
Externí odkaz:
https://doaj.org/article/75e6bcf8fca64eda847ae798cf893c23
Publikováno v:
Brain Sciences, Vol 12, Iss 9, p 1146 (2022)
Neurodegenerative parkinsonian disorders are characterized by a great diversity of clinical symptoms and underlying neuropathology, yet differential diagnosis during lifetime remains probabilistic. Molecular imaging is a powerful method to detect pat
Externí odkaz:
https://doaj.org/article/d40baeb370bb4e789c8a103d63339c94
Autor:
Fabian Schaible, Franziska Maier, Timo Marcel Buchwitz, Frank Schwartz, Marius Hoock, Eckhard Schönau, Miriam Libuda, Anke Hordt, Thilo van Eimeren, Lars Timmermann, Carsten Eggers
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 14 (2021)
Background: Parkinson’s disease (PD) patients experience disabling motor dysfunctions as well as non-motor symptoms (NMSs) that can highly impact their perceived quality of life. Besides pharmacological treatment options, active intervention progra
Externí odkaz:
https://doaj.org/article/e6642b2b7acb4f34b3a7b8ae38032b78
Autor:
Kenan Steidel, Marina C. Ruppert, Irina Palaghia, Andrea Greuel, Masoud Tahmasian, Franziska Maier, Jochen Hammes, Thilo van Eimeren, Lars Timmermann, Marc Tittgemeyer, Alexander Drzezga, David Pedrosa, Carsten Eggers
Publikováno v:
NeuroImage: Clinical, Vol 32, Iss , Pp 102899- (2021)
Freezing of gait is a common phenomenon of advanced Parkinson’s disease. Besides locomotor function per se, a role of cognitive deficits has been suggested. Limited evidence of associated dopaminergic deficits points to caudatal denervation. Furthe
Externí odkaz:
https://doaj.org/article/7029a6e36bca43fd9ca59b05ca98404c