Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Thilini Samarasinghe"'
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43165 (2012)
OBJECTIVES: The significance of blood pressure variability (BPV) for cerebral oxygenation in extremely preterm infants has not been explored, though BPV may well be associated with end organ injury. We hypothesized that increased BPV in sick preterm
Externí odkaz:
https://doaj.org/article/e425797168914d1e94f54e7375156073
Autor:
Susan Y. S. Feng, David James Phillips, Victor Y H Yu, Thilini Samarasinghe, Jacob Harvey Hollis, Shripada Rao, Adrian M. Walker
Publikováno v:
Physiological Reports
As the comparative pathophysiology of perinatal infection in the fetus and newborn is uncertain, this study contrasted the cerebral effects of endotoxemia in conscious fetal sheep and newborn lambs. Responses to intravenous bacterial endotoxin (lipop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f4a00823befd90fe012c31efcbeb1f
http://europepmc.org/articles/PMC6381816
http://europepmc.org/articles/PMC6381816
Autor:
Helen Romios, Bradley A. Edwards, Garun S. Hamilton, Darren Mansfield, Thilini Samarasinghe, Yvonne Ng, Shane A. Landry, Simon A. Joosten, Anthony Turton
The aim of this study was to compare the oxygen desaturation index (ODI) generated by two different sleep software systems.Participants undergoing diagnostic polysomnography for suspected obstructive sleep apnea underwent simultaneous oximetry record
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aefb3297c3ade4c5047aa8e861b310ea
https://europepmc.org/articles/PMC5359337/
https://europepmc.org/articles/PMC5359337/
Autor:
Thilini Samarasinghe, Alex Veldman, Niamh E. Mangan, Steven X. Cho, Ina Rudloff, John Pedersen, Nikeh Shariatian, Elizabeth M. Skuza, Marcel F. Nold, Philip J. Berger, Claudia A. Nold-Petry
Publikováno v:
Proceedings of the National Academy of Sciences. 110:14384-14389
Bronchopulmonary dysplasia (BPD) is a common lung disease of premature infants, with devastating short- and long-term consequences. The pathogenesis of BPD is multifactorial, but all triggers cause pulmonary inflammation. No therapy exists; therefore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c74b86739d0dbb09b32969133695fb8
https://doi.org/10.1073/pnas.1306859110
https://doi.org/10.1073/pnas.1306859110
Autor:
Philip J. Berger, Mandar S. Joshi, Duncan Horlock, Jaye Chin-Dusting, David M. Kaye, David R. Williams, Ann-Maree Jefferis, Thilini Samarasinghe, Karen L. Andrews
Publikováno v:
Diabetesvascular disease research. 12(3)
Microvascular complications are now recognized to play a major role in diabetic complications, and understanding the mechanisms is critical. Endothelial dysfunction occurs early in the course of the development of complications; the precise mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebd3f86b60f6930247c27eba98cc1c97
https://pubmed.ncbi.nlm.nih.gov/25767181
https://pubmed.ncbi.nlm.nih.gov/25767181
Autor:
Thilini Samarasinghe, Claudia A. Nold-Petry, Scott A. Sands, Elizabeth M. Skuza, Mandar S. Joshi, Philip J. Berger
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 119(3)
Systemic maternal inflammation is implicated in preterm birth and bronchopulmonary dysplasia (BPD) and may induce morbidities including reduced pulmonary function, sleep-disordered breathing, and cardiovascular disorders. Here we test the hypothesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df0bb96c9adfc343e8035d37fc5cc08
https://pubmed.ncbi.nlm.nih.gov/26023231
https://pubmed.ncbi.nlm.nih.gov/26023231
Autor:
Mandar S. Joshi, James C.G. Doery, Claudia A. Nold-Petry, Elisabeth Olhager, Thilini Samarasinghe, Adrian M. Walker, Flora Y. Wong
Publikováno v:
Acta paediatrica (Oslo, Norway : 1992). 103(3)
Aim Dopamine is used as an inotropic medication in preterm infants. The preterm human blood brain barrier (BBB) is permeable to intravascular dopamine, and the impact of exogenous dopamine on the preterm brain remains unknown. The preterm lamb model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d126a0c90d52a87b07151dbabce3794d
https://pubmed.ncbi.nlm.nih.gov/24267481
https://pubmed.ncbi.nlm.nih.gov/24267481
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43165 (2012)
PLoS ONE
PLoS ONE
OBJECTIVES: The significance of blood pressure variability (BPV) for cerebral oxygenation in extremely preterm infants has not been explored, though BPV may well be associated with end organ injury. We hypothesized that increased BPV in sick preterm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d240e90b9b0724f4aaf20fcc3326a6
http://europepmc.org/articles/PMC3419198?pdf=render
http://europepmc.org/articles/PMC3419198?pdf=render
Publikováno v:
Anesthesiology. 113(6)
Background Bedside assessments of cerebral oxygenation are sought to monitor cerebral injury in patients undergoing intensive care. Spatially resolved spectroscopy measures tissue oxygenation index (TOI, %) which reflects mixed cerebral arterial and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b13534704ba5b6817e252ce8727f367a
https://pubmed.ncbi.nlm.nih.gov/21068664
https://pubmed.ncbi.nlm.nih.gov/21068664
Autor:
Susan Ys Feng, Theodora Alexiou, Victor Y H Yu, Jacob Harvey Hollis, David James Phillips, Adrian M. Walker, Thilini Samarasinghe
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 298(3)
The impact of endotoxemia on cerebral endothelium and cerebral blood flow (CBF) regulation was studied in conscious newborn lambs. Bacterial endotoxin [LPS, 2 μg/kg iv] was infused on 3 consecutive days. Cerebrovascular function was assessed by moni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3afc645c7a5e8abe8d28841b3e352a39
https://pubmed.ncbi.nlm.nih.gov/20071615
https://pubmed.ncbi.nlm.nih.gov/20071615