Targeting PDGF-mediated recruitment of pericytes blocks vascular mimicry and tumor growth

Autor: Thijssen, Victor LJL, Paulis, Yvette WJ, Nowak-Sliwinska, Patrycja, Deumelandt, Katrin L, Hosaka, Kayoko, Soetekouw, Patricia MMB, Cimpean, Anca M, Raica, Marius, Pauwels, Patrick, van den Oord, Joost J, Tjan-Heijnen, Vivianne CG, Hendrix, Mary J, Heldin, Carl-Henrik, Cao, Yihai, Griffioen, Arjan W

Publikováno v: Thijssen, V L J L, Paulis, Y W J, Nowak-Sliwinska, P, Deumelandt, K L, Hosaka, K, Soetekouw, P M M B, Cimpean, A M, Raica, M, Pauwels, P, van den Oord, J J, Tjan-Heijnen, V C G, Hendrix, M J, Heldin, C-H, Cao, Y & Griffioen, A W 2018, ' Targeting PDGF-mediated recruitment of pericytes blocks vascular mimicry and tumor growth ', Journal of Pathology, vol. 246, no. 4, pp. 447-458 . https://doi.org/10.1002/path.5152
Journal of Pathology, 246(4), 447-458. Wiley
The Journal of Pathology
Journal of Pathology, 246(4), 447-458. John Wiley and Sons Ltd
The Journal of Pathology, Vol. 246, No 4 (2018) pp. 447-458
The journal of pathology

Aggressive tumor cells can adopt an endothelial cell-like phenotype and contribute to the formation of a tumor vasculature, independent of tumor angiogenesis. This adoptive mechanism is referred to as vascular mimicry and it is associated with poor s

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https://research.vumc.nl/en/publications/0a2bde55-0895-49ee-9b6a-f1d907174034