Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Thijs A. van Schaik"'
Autor:
Longsha Liu, Thijs A. van Schaik, Kok-Siong Chen, Filippo Rossignoli, Paulo Borges, Vladimir Vrbanac, Hiroaki Wakimoto, Khalid Shah
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/0147e1c4c66745aca653b8bc05b417bf
Autor:
Longsha Liu, Thijs A. van Schaik, Kok-Siong Chen, Filippo Rossignoli, Paulo Borges, Vladimir Vrbanac, Hiroaki Wakimoto, Khalid Shah
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Glioblastoma (GBM) is the most aggressive and common type of malignant brain tumor diagnosed in adults. Preclinical immunocompetent mouse tumor models generated using mouse tumor cells play a pivotal role in testing the therapeutic efficacy of emergi
Externí odkaz:
https://doaj.org/article/c16ec3ad8efe4e1c9db3f6de3db24ff5
Autor:
Thijs A. van Schaik, Lucia Moreno-Lama, Touraj Aligholipour Farzani, Mian Wang, Kok-Siong Chen, Wanlu Li, Ling Cai, Yu Shrike Zhang, Khalid Shah
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 162, Iss , Pp 114665- (2023)
Encapsulated cell-based therapies for solid tumors have shown promising results in pre-clinical settings. However, the inability to culture encapsulated therapeutic cells prior to their transplantation has limited their translation into clinical sett
Externí odkaz:
https://doaj.org/article/6c6df656e7074764b659171febf2ce77
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Combinatory treatments using surgery, radiotherapy and/or chemotherapy together with immunotherapy have shown encouraging results for specific subsets of tumors, but a significant proportion of tumors remains unsusceptible. Some of these inconsistenc
Externí odkaz:
https://doaj.org/article/2afd9c649b214a8c9f384dc7ef75cfdd
Autor:
Nobuhiko Kanaya, Yohei Kitamura, Maria Lopez Vazquez, Arnaldo Franco, Kok-Siong Chen, Thijs A. van Schaik, Touraj Aligholipour Farzani, Paulo Borges, Toru Ichinose, Waleed Seddiq, Shinji Kuroda, Genevieve Boland, Nusrat Jahan, David Fisher, Hiroaki Wakimoto, Khalid Shah
Publikováno v:
Science Translational Medicine. 15
Oncolytic virus therapy has shown activity against primary melanomas; however, its efficacy in brain metastases remains challenging, mainly because of the delivery and immunosuppressive nature of tumors in the brain. To address this challenge, we fir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::405a5a55ff9bb2ddac9645fc4b4b4ccc
https://doi.org/10.1126/scitranslmed.ade8732
https://doi.org/10.1126/scitranslmed.ade8732
Autor:
Kok-Siong Chen, Clemens Reinshagen, Thijs A. Van Schaik, Filippo Rossignoli, Paulo Borges, Natalia Claire Mendonca, Reza Abdi, Brennan Simon, David A. Reardon, Hiroaki Wakimoto, Khalid Shah
Publikováno v:
Sci Transl Med
The administration of inactivated tumor cells is known to induce a potent antitumor immune response; however, the efficacy of such an approach is limited by its inability to kill tumor cells before inducing the immune responses. Unlike inactivated tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635e68b3fc4b0d9481f248f64a708342
https://doi.org/10.1126/scitranslmed.abo4778
https://doi.org/10.1126/scitranslmed.abo4778
Autor:
Nobuhiko Kanaya, Kok Siong Chen, Yoshinori Kajiwara, Waleed Seddiq, Thijs A. van Schaik, Touraj Aligholipour Farzani, Paulo Borges, Shah Khalid
Publikováno v:
Cancer Research. 83:1816-1816
Patients with advanced melanoma have a high propensity to metastasize to the brain and numerous investigational treatments with targeted agents have shown modest response in melanoma brain metastatic patients. Leptomeningeal metastasis (LM) is one of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f6b75c1e1238b967b71711f210edde6
https://doi.org/10.1158/1538-7445.am2023-1816
https://doi.org/10.1158/1538-7445.am2023-1816