Genome-wide haplotyping embryos developing from 0PN and 1PN zygotes increases transferrable embryos in PGT-M

Autor: Masoud Zamani Esteki, Eric Legius, Cindy Melotte, Thomy de Ravel, Karen Peeraer, Joris Vermeesch, Christel Meuleman, Thiery Voet, Eftychia Dimitriadou, Ellen Denayer, Jia Ding, Sophie Debrock, Aspasia Destouni, Heleen Masset, Kris Van Den Bogaert

Publikováno v: Human Reproduction, 33(12), 2302-2311. Oxford University Press
Human Reproduction (Oxford, England)
Human Reproduction

STUDY QUESTION: Can genome-wide haplotyping increase success following preimplantation genetic testing for a monogenic disorder (PGT-M) by including zygotes with absence of pronuclei (0PN) or the presence of only one pronucleus (1PN)? SUMMARY ANSWER:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::852ee978305a2b6db1dd6979d88de266
https://doi.org/10.1093/humrep/dey325