Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Thierry. P. P. van den Bosch"'
Autor:
Anusha S. Shankar, Hector Tejeda-Mora, Zhaoyu Du, Quincy Nlandu, Virginia Palomares-Cabeza, Thierry P. P. van den Bosch, Sander S. Korevaar, Fabiany Da Costa Gonçalves, Eric M. J. Bindels, R. Kramann, Marlies E. J. Reinders, Marian C. Clahsen-van Groningen, Ewout J. Hoorn, Joost Gribnau, Carla C. Baan, Martin J. Hoogduijn
Publikováno v:
Transplant International, Vol 37 (2024)
Kidney organoids are an innovative tool in transplantation research. The aim of the present study was to investigate whether kidney organoids are susceptible for allo-immune attack and whether they can be used as a model to study allo-immunity in kid
Externí odkaz:
https://doaj.org/article/3cc42c074ba04f7f8e9f53cc968ab725
Autor:
Jochem K. H. Spoor, May den Braber, Clemens M. F. Dirven, Adam Pennycuick, Jirina Bartkova, Jiri Bartek, Vera van Dis, Thierry P. P. van den Bosch, Sieger Leenstra, Subramanian Venkatesan
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
BackgroundOnly a small group of patients with glioblastoma multiforme (GBM) survives more than 36 months, so-called long-term survivors. Recent studies have shown that chromosomal instability (CIN) plays a prognostic and predictive role among differe
Externí odkaz:
https://doaj.org/article/7782b16b268849169ecbcf4bca2fad8a
Autor:
Roberto Stabile, Mario Román Cabezas, Mathijs P. Verhagen, Francesco A. Tucci, Thierry P. P. van den Bosch, Maria J. De Herdt, Berdine van der Steen, Alex L. Nigg, Meng Chen, Cristina Ivan, Masayoshi Shimizu, Senada Koljenović, Jose A. Hardillo, C. Peter Verrijzer, Robert J. Baatenburg de Jong, George A. Calin, Riccardo Fodde
Publikováno v:
Cell Death and Disease, Vol 14, Iss 5, Pp 1-13 (2023)
Abstract Cyclin-dependent kinase 2-associated protein 1 (CDK2AP1; also known as deleted in oral cancer or DOC1) is a tumor suppressor gene known to play functional roles in both cell cycle regulation and in the epigenetic control of embryonic stem ce
Externí odkaz:
https://doaj.org/article/f7824d98a84b4c1d9d47b1294a00ba7e
Autor:
Pengfei Li, Zhaoyu Du, Mart M. Lamers, Roberto Incitti, Hector Tejeda-Mora, Shengbing Li, Rick Schraauwen, Thierry P. P. van den Bosch, Annemarie C. de Vries, Intikhab S. Alam, Bart L. Haagmans, Martin J. Hoogduijn, Qiuwei Pan
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/d34bb599ffb44742b8006cf507875066
Autor:
Roisin McMorrow, Giorgia Zambito, Alex Nigg, Karishma Lila, Thierry P. P. van den Bosch, Clemens W. G. M. Lowik, Laura Mezzanotte
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe location of T-cells during tumor progression and treatment provides crucial information in predicting the response in vivo.MethodsHere, we investigated, using our bioluminescent, dual color, T-cell reporter mouse, termed TbiLuc, T-cel
Externí odkaz:
https://doaj.org/article/0f75ebfaf13b4331997f2b66d1beefdf
Autor:
Shanshan Li, Ruyi Zhang, Marla Lavrijsen, Thierry P P van den Bosch, Maikel P Peppelenbosch, Ron Smits
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0283894 (2023)
RNF43 is an important negative regulator of β-catenin signaling by removing Wnt-receptors from the membrane. It is often mutated in cancers, leading to aberrant Wnt-dependent nuclear translocation of β-catenin. RNF43 has also been suggested to regu
Externí odkaz:
https://doaj.org/article/ffaa57bf4ed741ac98bf2cf01f42c568
Autor:
Jolien Van Cleemput, Willem van Snippenberg, Laurens Lambrechts, Amélie Dendooven, Valentino D’Onofrio, Liesbeth Couck, Wim Trypsteen, Jan Vanrusselt, Sebastiaan Theuns, Nick Vereecke, Thierry P. P. van den Bosch, Martin Lammens, Ann Driessen, Ruth Achten, Ken R. Bracke, Wim Van den Broeck, Jan Von der Thüsen, Hans Nauwynck, Jo Van Dorpe, Sarah Gerlo, Piet Maes, Janneke Cox, Linos Vandekerckhove
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Here the authors provide a detailed virological analysis of thirteen postmortem COVID-19 cases, including presence of replication-competent SARS-CoV-2 in extrapulmonary organs and tissue-specific patterns of SARS-CoV-2 genome diversity of an immunoco
Externí odkaz:
https://doaj.org/article/d7ddc26aed524990a6ce3aa009110d7b
Autor:
Denise van Uden, Thomas Koudstaal, Jennifer A. C. van Hulst, Thierry P. P. van den Bosch, Madelief Vink, Ingrid M. Bergen, Karishma A. Lila, Annemien E. van den Bosch, Paul Bresser, Mirjam Kool, Jan H. von der Thüsen, Rudi W. Hendriks, Karin A. Boomars
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionPrevious studies have shown an increase of T cells and chemokines in vascular lesions of patients with chronic thromboembolic pulmonary hypertension (CTEPH). However, detailed characterization of these T cells is still lacking, nor have t
Externí odkaz:
https://doaj.org/article/75ddaec85a8b4c6b8a6a50fcf91283fc
Identifying Molecular Changes in Early Cervical Cancer Samples of Patients That Developed Metastasis
Autor:
Vera de Geus, Patricia C. Ewing-Graham, Willem de Koning, Maurits N. C. de Koning, Thierry P. P. van den Bosch, Alex L. Nigg, Casper H. J. van Eijck, Marta Jozwiak, Heleen J. van Beekhuizen, Dana A. M. Mustafa
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Cervical cancer is one of the most common cancers in women worldwide. Patients diagnosed with early-stage cervical cancer have a good prognosis, however, 10-20% suffer from local or distant recurrent disease after primary treatment. Treatment options
Externí odkaz:
https://doaj.org/article/83c09f01613e4e1dbc7b273099940269
Autor:
Michelle Broekhuizen, Emilie Hitzerd, Thierry P. P. van den Bosch, Jasper Dumas, Robert M. Verdijk, Bas B. van Rijn, A. H. Jan Danser, Casper H. J. van Eijck, Irwin K. M. Reiss, Dana A. M. Mustafa
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Preeclampsia is a severe placenta-related pregnancy disorder that is generally divided into two subtypes named early-onset preeclampsia (onset
Externí odkaz:
https://doaj.org/article/3aa395aaf12f46ff9ecebd5b5edee77b